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Preparation H

Preparation H 26GM of 1-0.25-14.4-15%

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What is Preparation H?

Preparation H is an over-the-counter medication primarily used to relieve the discomfort associated with hemorrhoids. It contains active ingredients such as phenylephrine, which reduces swelling, and pramoxine, which alleviates pain and itching. Preparation H is available in various forms, including creams, gels, and suppositories, making it versatile for different needs.

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What is Preparation H ?

Preparation H is an over-the-counter medication primarily used to relieve the discomfort associated with hemorrhoids. It contains active ingredients such as phenylephrine, which reduces swelling, and pramoxine, which alleviates pain and itching. Preparation H is available in various forms, including creams, gels, and suppositories, making it versatile for different needs.
  • Mild pain or irritation
  • Burning sensation
  • Do not use if you have an allergic reaction to the components of the product.
  • Consult a doctor if symptoms do not improve within 7 days.
What is the difference between Preparation H Original and Maximum Strength?
Original combines the vasoconstrictor phenylephrine HCl with protectants like mineral oil and petrolatum to shrink hemorrhoidal tissue and soothe irritation. Maximum Strength uses that same phenylephrine base but adds pramoxine HCl, a local anesthetic, for additional numbing relief from pain and discomfort.
Can you use Preparation H on your face or under-eye bags?
Preparation H is labeled for external and perianal use for hemorrhoid symptoms only. It is not an FDA-approved facial or cosmetic product, so using it on the face or under the eyes falls outside its labeled use. Talk to a doctor or dermatologist about products actually indicated for facial skin.
How long can you safely use Preparation H?
The label says to stop and consult a doctor if symptoms don't improve within 7 consecutive days of use, or sooner if you notice bleeding. It isn't meant for indefinite, ongoing use without a doctor's direction, and hydrocortisone-containing formulas in particular shouldn't be used long-term because of skin-thinning risk.
Does Preparation H shrink hemorrhoids or just relieve symptoms?
It depends on the formula. Products containing phenylephrine (a vasoconstrictor), such as Original and Maximum Strength, are labeled to temporarily shrink hemorrhoidal tissue in addition to relieving itching and discomfort. The Anti-Itch formula, which uses hydrocortisone alone instead, is aimed at relieving itching and irritation rather than shrinking tissue.
Is Preparation H safe to use during pregnancy?
The label advises consulting a doctor before use if you are pregnant. Since formulas differ in active ingredients (phenylephrine, pramoxine, or hydrocortisone), the safest approach is to ask your doctor or pharmacist which formula, if any, is appropriate for your situation before using it.
How much does Preparation H cost without insurance?
The price of Preparation H without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 63% off retail prices with a free Rx.com coupon.
What are the common side effects of Preparation H?
Common side effects of Preparation H may include: Mild pain or irritation, Burning sensation. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Preparation H?
Generic versions may be available for Preparation H. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Preparation H on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Preparation H?
The cheapest pharmacy for Preparation H depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Preparation H near you.

Preparation H Coupons & Prices

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Preparation H is an over-the-counter hemorrhoid treatment sold in several formulas (Original, Maximum Strength, Anti-Itch, Cooling Gel, and Medicated Wipes), and you don't need a prescription to buy it, so a preparation-h coupon can still help you compare pharmacy prices before you check out. Because store-brand versions of the same active ingredients exist, entering your ZIP above lets you see today's price at nearby pharmacies and decide whether the brand name or a generic makes more sense for you.

What Preparation H is and how it works

Preparation H isn't a single formula but a line of topical, external-use products for hemorrhoid symptoms. The Original line combines phenylephrine HCl, a vasoconstrictor that temporarily shrinks hemorrhoidal tissue, with protectants such as mineral oil and petrolatum that soothe irritated skin. Maximum Strength adds pramoxine HCl, a local anesthetic, to that phenylephrine base for extra numbing relief. The Anti-Itch line uses hydrocortisone (a topical corticosteroid) alone, aimed specifically at itching rather than swelling.

All of these are regulated under an FDA OTC monograph for anorectal products, meaning they're approved for temporary relief of itching, burning, discomfort, irritation, and swelling from hemorrhoids or minor anal fissures. They aren't intended to treat any internal or systemic condition.

Comparing pharmacy prices and generic options

Because Preparation H is sold over the counter, prices can vary quite a bit from one pharmacy to the next, and store-brand or generic versions with the same active ingredients (phenylephrine, pramoxine, or hydrocortisone) are generally available. Since this isn't a prescription product, there's no manufacturer copay card to apply here, but it's still worth entering your ZIP code above to compare what different nearby pharmacies charge for the brand name versus a generic equivalent before you buy.

Alternatives and related treatments

Depending on which symptom bothers you most, other OTC options treat similar hemorrhoid or anorectal complaints. Plain hydrocortisone cream can address itching on its own, witch-hazel pads are a common astringent alternative for soothing irritated tissue, and Anusol is another OTC anorectal product formulated for similar symptoms. If numbing is the priority, topical lidocaine products are another local anesthetic option. None of these are direct substitutes for every Preparation H variant, so match the active ingredient to the symptom you're treating, or ask a pharmacist which fits your situation.

Safety and when to see a doctor

Preparation H products are for external and perianal use only and should not contact the eyes. The label advises stopping and consulting a doctor if you notice rectal bleeding, your symptoms don't improve within 7 days, or you need it for longer than that without medical guidance. Hydrocortisone-containing formulas (Anti-Itch) shouldn't be used for prolonged periods because of the risk of skin thinning. Anyone with heart disease, high blood pressure, or thyroid disease, or who takes an MAOI, should check with a doctor before using phenylephrine-containing formulas, since phenylephrine is a vasoconstrictor. Keep it out of reach of children, and this information isn't a substitute for talking with your doctor or pharmacist about your specific situation.

Sources & accuracy

This Preparation H information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Preparation H on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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