Impact-Site-Verification: 2721d812-1059-4270-b9fa-5c1654788cd1

Prevident 5000 Bottle — prescription drug image

Prevident 5000

Prevident 5000 100ML of 1.1%

Prescriptions & Refills
Licensed US providers · Online visit in minutes

What is Prevident 5000?

PreviDent 5000 is a prescription-strength 1.1% sodium fluoride toothpaste used to help prevent cavities, strengthen tooth enamel, and reduce the risk of tooth decay in patients at high risk for dental caries. It contains approximately 5,000 ppm fluoride, about four times the fluoride found in most over-the-counter toothpastes, making it an effective option for protecting teeth and promoting enamel remineralization. 

Prescription savings · · · ·

What is Prevident 5000 ?

PreviDent 5000 is a prescription-strength 1.1% sodium fluoride toothpaste used to help prevent cavities, strengthen tooth enamel, and reduce the risk of tooth decay in patients at high risk for dental caries. It contains approximately 5,000 ppm fluoride, about four times the fluoride found in most over-the-counter toothpastes, making it an effective option for protecting teeth and promoting enamel remineralization. 

  • Burning in your mouth, sore tongue.
  • Nausea, vomiting, or diarrhea.
  • Vomiting blood.
  • Make sure your doctor knows if you are pregnant or breast feeding. Tell your doctor if you are allergic to any foods, preservatives, or dyes.
  • Too much fluoride can cause white patches or stains on your teeth. If this happens, stop using the medicine and call your doctor.
  • If this medicine is being used by a child, an adult should watch the child and make sure they do not swallow the medicine. If they swallow too much of the medicine, it can cause fluoride toxicity. Ask your health caregiver if you have questions or concerns about this.
Is PreviDent 5000 available over the counter or does it require a prescription?
PreviDent 5000 requires a prescription. At 1.1% sodium fluoride (about 5,000 ppm), it contains far more fluoride than over-the-counter toothpaste, so it must be prescribed by a dentist or physician. Over-the-counter toothpastes typically contain much lower fluoride levels.
How is PreviDent 5000 different from regular toothpaste?
PreviDent 5000 contains 1.1% sodium fluoride (about 5,000 ppm), which is several times the fluoride found in standard over-the-counter toothpaste. That higher concentration is designed to remineralize weakened enamel and exposed roots and to give extra cavity protection for people at high risk of decay, which is why it needs a prescription.
How often should you use PreviDent 5000?
It is typically used once daily in place of your regular toothpaste - brushing with a thin, pea-sized ribbon - though your dentist may give you specific directions. Always follow the instructions on your prescription and from your dental provider.
Should you rinse your mouth after using PreviDent 5000?
No. For the best effect, spit out the excess but do not rinse, eat, or drink for 30 minutes after brushing. This lets the fluoride stay in contact with your teeth longer so it can strengthen the enamel. Remember it is for topical use only and should not be swallowed.
Is there a generic version of PreviDent 5000?
Yes. Lower-cost generic 1.1% sodium fluoride dentifrices are available. They contain the same active ingredient at the same strength and usually cost less, so ask your dentist or pharmacist whether a generic is right for you. Enter your ZIP code above to see today's price.
How much does Prevident 5000 100ML of 1.1% cost without insurance?
The price of Prevident 5000 100ML of 1.1% without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 46% off retail prices with a free Rx.com coupon.
What are the common side effects of Prevident 5000 100ML of 1.1%?
Common side effects of Prevident 5000 100ML of 1.1% may include: Burning in your mouth, sore tongue., Nausea, vomiting, or diarrhea., Vomiting blood.. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Prevident 5000 100ML of 1.1%?
Generic versions may be available for Prevident 5000 100ML of 1.1%. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Prevident 5000 100ML of 1.1% on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Prevident 5000 100ML of 1.1%?
The cheapest pharmacy for Prevident 5000 100ML of 1.1% depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Prevident 5000 100ML of 1.1% near you.

Prevident 5000 Coupons & Prices

Prevident 5000 100ML of 1.1%

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Prevident 5000 Bottle — prescription drug image
Prescription
Prevident 5000 100ml of 1.1% (1)
your area ·
Prescription weight loss

Weight-loss medication, prescribed online

Licensed U.S. providers · No insurance needed · Shipped to your door

$146/mo vs. brand-name GLP-1 medications $1,300+/mo Save up to 88%
See if I qualify Free online visit · No commitment
Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Prevident 5000 prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
100ml of 1.1% · Bottle 100 $45.99 $24.64
100ml of 1.1-5% · Bottle 100 $45.99 $24.64

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for a PreviDent 5000 coupon? PreviDent 5000 is a prescription-strength 1.1% sodium fluoride (5,000 ppm) toothpaste or gel used to help prevent cavities and remineralize weakened tooth enamel and exposed root surfaces. It's often prescribed for people at high risk for tooth decay, including those with dry mouth, braces, or a history of frequent cavities. Because it requires a prescription, you can use an Rx.com cash coupon to save at the pharmacy counter, even without insurance. Enter your ZIP code above to see today's price at pharmacies near you.

What is PreviDent 5000 and how does it work?

PreviDent 5000 is a family of prescription-strength fluoride dental products made with 1.1% sodium fluoride, which equals about 5,000 parts per million (ppm) of fluoride. That is far more fluoride than an over-the-counter toothpaste. The extra fluoride helps rebuild (remineralize) enamel that has started to weaken and makes teeth more resistant to the acids that cause cavities. It is used as an aid in preventing dental caries in adults and children ages 6 and older.

There are several formulations to fit different needs:

  • PreviDent 5000 Plus and PreviDent 5000 Booster Plus - everyday prescription-strength cavity prevention.
  • PreviDent 5000 Sensitive - adds 5% potassium nitrate to help reduce tooth sensitivity to cold, heat, sweets, and acids (for ages 12 and older).
  • PreviDent 5000 Dry Mouth - formulated to support remineralization in people with xerostomia (dry mouth).

Dentists commonly prescribe it for patients with dry mouth, orthodontic appliances, exposed roots, xerostomia caused by medications or radiation, or a history of frequent cavities.

PreviDent 5000 cost: manufacturer savings vs. Rx.com cash coupon

Colgate, the maker of PreviDent 5000, does not offer a standard manufacturer copay savings card for this product the way many brand-name prescription drugs do. Even when a brand does run a savings program, those cards are generally limited to people with commercial (non-government) insurance, and the terms vary and can change at any time. That leaves cash-pay shoppers, uninsured patients, and people on Medicare or Medicaid without a good option through the manufacturer.

An Rx.com cash coupon is different: it works whether or not you have insurance, and it is especially useful if you are uninsured, on Medicare, or if a savings card is declined at the counter. You simply present the coupon at the pharmacy to pay the discounted cash price. The biggest savings lever here is the generic: PreviDent 5000 is prescription-strength 1.1% sodium fluoride, and lower-cost generic 1.1% sodium fluoride dentifrices are widely available and usually cost much less than the brand. Ask your dentist or pharmacist whether a generic is right for you. Enter your ZIP code above to see today's price at pharmacies near you.

Alternatives and related fluoride products

PreviDent 5000 is one of several prescription-strength 1.1% sodium fluoride dentifrices. If your dentist prescribes prescription-strength fluoride, you may be offered a comparable product or a lower-cost generic. Related options include:

  • Clinpro 5000 - a prescription 1.1% sodium fluoride toothpaste that also contains functionalized tricalcium phosphate.
  • Denta 5000 Plus - another prescription-strength 1.1% sodium fluoride toothpaste.
  • Sodium fluoride - the active ingredient; lower-cost generic 1.1% sodium fluoride dentifrices are available and are usually the lowest-cost choice.
  • Fluoride - the broader class of fluoride dental products, including prescription and over-the-counter forms.

These products all deliver the same 1.1% sodium fluoride strength, so the main differences come down to added ingredients (such as potassium nitrate for sensitivity or tricalcium phosphate), flavor, and price. Your dentist or pharmacist can tell you which is the best fit and whether a lower-cost generic is appropriate.

Safety and how to use PreviDent 5000

PreviDent 5000 is for topical use only - do not swallow it. Use only a thin ribbon (about pea-sized) on a toothbrush, typically once daily in place of your regular toothpaste (follow your dentist's directions). For the best effect, do not eat, drink, or rinse for 30 minutes after brushing. It is not for children under 6 unless directed by a dentist or physician, because young children who swallow too much fluoride while their teeth are developing can get dental fluorosis (mottling of the teeth). Keep it out of reach of children, and if a large amount is accidentally swallowed, contact Poison Control at 1-800-222-1222. With the Sensitive formulation, if tooth sensitivity persists beyond 4 weeks, see your dentist. PreviDent 5000 has no boxed warning.

Note: In May 2025 the FDA announced its intent to remove ingestible (swallowed) prescription fluoride supplements for children from the market. That action concerns systemic fluoride supplements you swallow, not topical dentifrices like PreviDent 5000, which stay in the mouth and are spit out. This page is educational and not medical advice - talk with your dentist or provider about what is right for you.

Sources & accuracy

This Prevident 5000 information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Prevident 5000 on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

Sponsored
Sesame Care — 350+ medications for $1 without insurance
¿Buscando esta página en español?

Related Drugs

Browse more medications: starting with P · full A-Z directory · by condition · common drugs

Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


Don't Miss Out On Savings!