Stendra
Stendra
4 ED medications in one dose
Sildenafil, tadalafil, PT-141 & L-Citrulline in one sublingual dose · Works in ~15 min · Lasts up to 36 hours
What is Stendra?
Stendra (avanafil) is a prescription medication used to treat erectile dysfunction (ED) in adult men. It works by increasing blood flow to the penis during sexual stimulation. Common side effects may include headache, flushing, or stuffy nose. You can connect with a licensed provider for your prescription online at Rx.com and explore options for cost savings and mail-order refills.
Side Effects
- Lightheadedness or fainting
- Sudden loss of vision in one or both eyes
- Sudden hearing loss, ringing in your ears, or dizziness
Warnings
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- This medicine will not protect you from sexually transmitted infections (including HIV or AIDS).
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- This medicine will not protect you from sexually transmitted infections (including HIV or AIDS).
Prescription savings · · · ·
What is Stendra ?
Stendra (avanafil) is a prescription medication used to treat erectile dysfunction (ED) in adult men. It works by increasing blood flow to the penis during sexual stimulation. Common side effects may include headache, flushing, or stuffy nose. You can connect with a licensed provider for your prescription online at Rx.com and explore options for cost savings and mail-order refills.
- Lightheadedness or fainting
- Sudden loss of vision in one or both eyes
- Sudden hearing loss, ringing in your ears, or dizziness
- Painful erection or an erection that lasts longer than 4 hours with or without pain
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chest pain, especially if it spreads to your jaw or arm, trouble breathing, nausea, unusual sweating
- Fast, pounding, or uneven heartbeat
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- This medicine will not protect you from sexually transmitted infections (including HIV or AIDS).
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- This medicine will not protect you from sexually transmitted infections (including HIV or AIDS).
- Tell your doctor if you have kidney disease, liver disease, bleeding problems, diabetes, heart or blood vessel disease, high blood pressure, high cholesterol, vision or eye problems, cancer (including leukemia, multiple myeloma), stomach ulcer, or a penis with an abnormal shape. Tell your doctor if you have sickle cell anemia, leukemia, or multiple myeloma. Tell your doctor if you have angina or chest pain during sex, heart disease, heart rhythm problems, high or low blood pressure, or a history of heart attack or stroke.
- This medicine may cause the following problems: Low blood pressure (especially if taken with other medicines that lower blood pressure)Painful or prolonged erectionHearing or vision problems
Stendra Coupons & Prices
Stendra
4 ED medications in one dose
Sildenafil, tadalafil, PT-141 & L-Citrulline in one sublingual dose · Works in ~15 min · Lasts up to 36 hours
4 ED medications in one dose
Sildenafil, tadalafil, PT-141 & L-Citrulline · Works in ~15 min · Lasts up to 36 hours
Looking for a Stendra coupon? Rx.com offers a free cash-price coupon on Stendra (avanafil), the fast-onset PDE5 inhibitor FDA-approved to treat erectile dysfunction (ED) in adult men. Our coupon works at the pharmacy counter whether or not you have insurance, and the FDA-approved generic, avanafil, is now on the market as a lower-cost option. Enter your ZIP above to see today's price at pharmacies near you.
What is Stendra (avanafil) and how does it work?
Stendra is the brand name for avanafil, a phosphodiesterase type 5 (PDE5) inhibitor. It is FDA-approved to treat erectile dysfunction (ED) in adult men. Like other PDE5 inhibitors, avanafil improves blood flow to the penis when a man is sexually aroused, helping him get and keep an erection. It only works with sexual stimulation.
One thing that sets avanafil apart is its fast onset: depending on the dose, it can be taken as soon as about 15 to 30 minutes before sexual activity. Stendra is not approved for use in women, and unlike some other drugs in its class it is not approved to treat pulmonary hypertension. Always take it exactly as your provider directs.
Stendra cost: manufacturer savings card vs. Rx.com cash coupon
The maker of Stendra runs an official manufacturer savings program, described on the brand's website at stendra.com. Manufacturer copay cards like this are generally limited to people with commercial (private) insurance, and the terms, eligibility, and expiration vary and can change, so read the current details before you rely on one. These cards typically cannot be used if you are uninsured or covered by Medicare, Medicaid, or another government program.
That is where the free Rx.com cash coupon helps. It is a cash-price discount, so it works for people who are uninsured, on Medicare, or whose commercial copay card is declined or has run out. You simply show the coupon at the pharmacy instead of running the claim through insurance. The biggest savings lever, though, is the generic: an FDA-approved generic avanafil is now marketed in the US, and asking your prescriber and pharmacist about the generic is usually the single best way to lower your out-of-pocket cost. Enter your ZIP above to see today's price on both Stendra and generic avanafil at pharmacies near you.
How Stendra compares to other ED medications
Stendra belongs to the same PDE5-inhibitor family as several other well-known ED treatments. They all improve blood flow with sexual stimulation, but they differ in how fast they start working and how long they last:
- avanafil — the generic form of Stendra itself, and typically the lowest-cost way to get this exact medicine.
- sildenafil (brand Viagra) — the original PDE5 inhibitor, taken before activity.
- tadalafil (brand Cialis) — known for a longer duration of action.
- vardenafil — another short-acting option.
There is no single "best" ED drug for everyone; the right choice depends on how quickly you want it to work, how long you want the effect to last, your other medicines, and your health history. Talk with your provider about which option fits you. This is general information, not medical advice.
Stendra safety: important warnings and interactions
Do not take Stendra with any form of nitrate medicine (such as nitroglycerin or isosorbide) or with riociguat (a guanylate cyclase stimulator). Combining them can cause a severe, potentially fatal drop in blood pressure. Use caution if you take alpha-blockers or other blood-pressure medicines, because avanafil can add to their blood-pressure-lowering effect. Strong CYP3A4 inhibitors (for example ketoconazole or ritonavir) can raise avanafil levels, so your dose may need to be lowered or the drug avoided. Limit alcohol, which can worsen these effects.
Seek emergency care for an erection lasting more than 4 hours (priapism). Rare but serious side effects reported with PDE5 inhibitors include a sudden decrease or loss of vision (NAION) and sudden hearing loss — stop the drug and get medical help if these occur. Because sexual activity puts extra demand on the heart, men with cardiovascular disease should check with a provider before use. Tell your prescriber about all your medicines and conditions. This is not medical advice; talk with your doctor or pharmacist about what is safe for you.
This Stendra information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Stendra on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.