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Sulfacetamide Sodium

Sulfacetamide Sodium 15ML of 10%

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What is Sulfacetamide Sodium?

Sulfacetamide sodium is a sulfonamide antibiotic commonly used in topical formulations to treat bacterial infections of the skin and eyes. It works by inhibiting the growth of bacteria by interfering with their ability to produce folic acid, essential for bacterial proliferation. Sulfacetamide sodium is particularly effective against a broad spectrum of gram-positive and gram-negative organisms, making it a versatile choice in treating conditions like conjunctivitis, blepharitis, and certain skin-related infections.

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What is Sulfacetamide Sodium ?

Sulfacetamide sodium is a sulfonamide antibiotic commonly used in topical formulations to treat bacterial infections of the skin and eyes. It works by inhibiting the growth of bacteria by interfering with their ability to produce folic acid, essential for bacterial proliferation. Sulfacetamide sodium is particularly effective against a broad spectrum of gram-positive and gram-negative organisms, making it a versatile choice in treating conditions like conjunctivitis, blepharitis, and certain skin-related infections.
  • Nausea or vomiting.
  • Joint pains.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash.
  • Fever, or soreness in your mouth.
  • Make sure your doctor knows if you are pregnant or breast feeding, or if you have a fungus infection. If you have any open wounds on the area you are going to treat, ask your doctor before using this medicine.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
  • Joint pains.
  • Nausea or vomiting.
What is sulfacetamide sodium used for?
Sulfacetamide sodium alone (such as Klaron 10% lotion) is FDA-labeled for the topical control of acne vulgaris. Sulfacetamide sodium combined with sulfur (Plexion, Rosula, Sumaxin, and similar products) is labeled for acne vulgaris, acne rosacea, and seborrheic dermatitis.
Is sulfacetamide sodium a sulfa drug and is it safe if I have a sulfa allergy?
Yes, sulfacetamide sodium is a sulfonamide (sulfa) drug. It's contraindicated in anyone with a known hypersensitivity to sulfonamides or sulfur. If you have a sulfa allergy, tell your prescriber and pharmacist before starting this medication so they can help you decide whether it's appropriate.
How is sodium sulfacetamide different from sodium sulfacetamide with sulfur?
Sulfacetamide sodium alone works as an antibacterial and is labeled for acne vulgaris. When it's combined with sulfur, the sulfur adds a keratolytic (skin-shedding) effect, and the combination product is also labeled for acne rosacea and seborrheic dermatitis, not just acne. Which one is prescribed depends on your specific skin condition.
How long does it take for sulfacetamide sodium to work on acne?
Response time varies from person to person, and it isn't specified as a set number of days or weeks on the label. As with most topical acne treatments, it typically takes consistent daily use over some time before you notice improvement. Follow your dermatologist's instructions and check in with them if you aren't seeing the results they expected by the timeframe they gave you.
Is sulfacetamide sodium available over the counter or does it require a prescription?
Sulfacetamide sodium topical products are prescription-only; they are not available over the counter.
How much does Sulfacetamide Sodium cost without insurance?
The price of Sulfacetamide Sodium without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Sulfacetamide Sodium?
Common side effects of Sulfacetamide Sodium may include: Nausea or vomiting., Joint pains., Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Blistering, peeling, red skin rash., Fever, or soreness in your mouth.. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Sulfacetamide Sodium?
Generic versions may be available for Sulfacetamide Sodium. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Sulfacetamide Sodium on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Sulfacetamide Sodium?
The cheapest pharmacy for Sulfacetamide Sodium depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Sulfacetamide Sodium near you.

Sulfacetamide Sodium Coupons & Prices

Sulfacetamide Sodium 15ML of 10%

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Sulfacetamide Sodium Bottle — prescription drug image
Prescription
Sulfacetamide Sodium 15ml of 10% (0.8)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

If your dermatologist prescribed sulfacetamide sodium — sold as the brand Klaron, or combined with sulfur under names like Plexion, Rosula, and Sumaxin — for acne or a related skin condition, a sulfacetamide sodium coupon can help you find the best price nearby before you fill it. Pharmacy prices for topical prescriptions like this one vary widely from one store to the next, so comparing matters. Rx.com compares pricing across more than 60,000 U.S. pharmacies — enter your ZIP above to see today's price near you.

What Is Sulfacetamide Sodium and How Does It Work?

Sulfacetamide sodium is a topical sulfonamide antibacterial. It works by blocking a substance (PABA) that certain acne-causing bacteria need to grow, which is why it's FDA-labeled for the topical control of acne vulgaris — the brand Klaron, for example, is a 10% lotion used for this purpose. Many sulfacetamide sodium products are combined with sulfur, which adds a keratolytic (skin-shedding) effect; these combination products, sold under names like Plexion, Rosula, Sumaxin, Avar, and Clenia, are also FDA-labeled for acne rosacea and seborrheic dermatitis.

Sulfacetamide sodium is prescription-only and is applied to the skin, not the eyes, unless a specific product is labeled for ophthalmic use.

Sulfacetamide Sodium Cost and Coupons

Generic sulfacetamide sodium products are available, alongside brand-name options like Klaron and the sulfacetamide/sulfur combination brands. Because this is a prescription topical, out-of-pocket cost without insurance can differ significantly depending on which pharmacy you use and whether you're filling the sulfacetamide-only or sulfacetamide/sulfur version. The most reliable way to know what you'll actually pay is to compare pharmacies directly — enter your ZIP code above and Rx.com will show you current pricing at pharmacies near you.

Other Topical Acne Treatments

Sulfacetamide sodium is one of several prescription topical options dermatologists use for acne, and the right choice depends on your skin, the type of breakouts, and what else you're using. Other commonly prescribed topical acne treatments include clindamycin and erythromycin (topical antibiotics), benzoyl peroxide and azelaic acid, tretinoin (a retinoid), and, for rosacea specifically, topical metronidazole. Ask your provider whether one of these is a better fit or whether it's reasonable to use alongside your current prescription.

Sulfacetamide Sodium Safety Information

Sulfacetamide sodium should not be used by anyone with a known hypersensitivity to sulfonamides or sulfur, or by patients with kidney disease. Rare but serious sulfonamide hypersensitivity reactions — including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood disorders — have been reported and are noted on the label as a class warning, even though they occur mostly with oral sulfonamides; fatalities from these reactions are rare. Some formulations also contain sodium metabisulfite, which can trigger allergic-type, anaphylactic, or asthmatic reactions in people who are sulfite-sensitive.

  • Local skin reactions — redness, scaling, dryness, or stinging — are common and expected with use.
  • Use sun protection, since sulfacetamide sodium can increase photosensitivity.
  • Safety hasn't been established in children under 12 for most of these products.

This is general information, not medical advice — talk to your prescriber or pharmacist about whether sulfacetamide sodium is right for you and how to use it safely.

Sources & accuracy

This Sulfacetamide Sodium information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Sulfacetamide Sodium on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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