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Temozolomide Capsule — prescription drug image

Temozolomide

Temozolomide 100MG

What is Temozolomide?

Temodar is a cancer medication used to treat brain tumors. Temozolomide is the generic version of Temodar. The average price of Temodar is around $1,056 for a supply of 1, 100 mg powder for injection. Use our Rx.com savings offer to get great discounts on Temodar at participating pharmacies near you.

Prescription savings · · · ·

What is Temozolomide ?

Temodar is a cancer medication used to treat brain tumors. Temozolomide is the generic version of Temodar. The average price of Temodar is around $1,056 for a supply of 1, 100 mg powder for injection. Use our Rx.com savings offer to get great discounts on Temodar at participating pharmacies near you.
  • Seizures
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash
  • Dark urine or pale stools, loss of appetite, stomach pain, yellow skin or eyes
  • Fever, chills, cough, sore throat, body aches
  • Severe nausea or vomiting
  • Unusual bleeding, bruising, or weakness
  • Oral routeThis medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before starting this medicine. Use an effective form of birth control during treatment and for at least 6 months after your last dose. Males with female partners who are able to become pregnant should use an effective form of birth control during treatment and for 3 months after the last dose.
  • Do not breastfeed during treatment and for 1 week after the last dose.
  • Tell your doctor if you have kidney disease, liver disease, anemia or any blood cell problems, or any type of infection.
  • This medicine may cause the following problems:Increased risk of pneumoniaIncreased risk of blood problems or other cancersLiver problems
  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
  • Talk with your doctor before using this medicine if you plan to have children. Some men using this medicine have become infertile (unable to have children).
  • Men should not donate semen during treatment and for at least 3 months after the final dose of this medicine.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
Is temozolomide the same as Temodar?
Temodar is the brand name for temozolomide. Generic temozolomide capsules have been FDA-approved and available since 2013 and are considered equivalent to the brand.
What is temozolomide used for?
As a capsule, it's FDA-approved to treat newly diagnosed glioblastoma (with radiation therapy, then as maintenance), newly diagnosed anaplastic astrocytoma as adjuvant treatment, and anaplastic astrocytoma that has progressed after prior chemotherapy.
Does temozolomide affect blood counts?
Yes. Myelosuppression is a serious risk listed under temozolomide's Warnings and Precautions, meaning it can lower blood cell counts, sometimes seriously. Your care team will check your blood counts regularly during treatment.
Is temozolomide taken by mouth or given by IV?
Temozolomide is available both as an oral capsule and as an intravenous infusion. This page is about the oral capsule form; the two forms are used and dosed differently.
Is temozolomide a controlled substance?
No, temozolomide is not a controlled substance, but it is a chemotherapy drug that requires close monitoring by an oncology specialist.
How much does Temozolomide cost without insurance?
The price of Temozolomide without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 97% off retail prices with a free Rx.com coupon.
What are the common side effects of Temozolomide?
Common side effects of Temozolomide may include: Seizures, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Blistering, peeling, or red skin rash, Dark urine or pale stools, loss of appetite, stomach pain, yellow skin or eyes, Fever, chills, cough, sore throat, body aches. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Temozolomide?
Generic versions may be available for Temozolomide. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Temozolomide on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Temozolomide?
The cheapest pharmacy for Temozolomide depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Temozolomide near you.

Temozolomide Coupons & Prices

Temozolomide 100MG

Temozolomide Capsule — prescription drug image
Prescription
Temozolomide 100mg (5)
your area ·

Temozolomide prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
5mg · Capsule 5 $88.99 $12.42
20mg · Capsule 5 $313.99 $24.44
100mg · Capsule 5 $1,592.70 $50.76
140mg · Capsule 5 $2,135.19 $60.44
180mg · Capsule 5 $2,855.83 $94.68
250mg · Capsule 5 $899.99 $97.90

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Temozolomide (brand name Temodar) is an oral chemotherapy capsule used to treat certain brain tumors. Because it's a specialty medication, cost and pharmacy availability can vary widely, and a temozolomide coupon can help whether you're filling the generic or the brand. Enter your ZIP above to see today's price near you.

What Is Temozolomide and How Does It Work?

Temozolomide is an alkylating chemotherapy drug taken by mouth as a capsule. This page covers the oral capsule form only; temozolomide is also available as an intravenous infusion given in a clinical setting, which has its own separate use and dosing and is not what this coupon applies to.

Temozolomide capsules are FDA-approved for adults with newly diagnosed glioblastoma, used together with radiation therapy and then continued as maintenance treatment, for adults with newly diagnosed anaplastic astrocytoma as adjuvant treatment, and for adults with anaplastic astrocytoma whose disease has progressed after treatment with a nitrosourea-based and procarbazine-based regimen.

How to Save on Temozolomide

A generic version of temozolomide capsules has been FDA-approved and available since 2013, made by several manufacturers, alongside the brand-name Temodar. Because this is a specialty oncology medication, it's typically dispensed through a specialty pharmacy rather than a retail counter, and pricing can vary significantly between pharmacies. Comparing prices, including with a coupon, can still make a real difference in what you pay out of pocket.

Temozolomide: Brand vs. Generic

  • Both the brand (Temodar) and generic temozolomide capsules are FDA-approved and currently marketed in the US.
  • Your oncology team and insurance plan typically determine which version you're dispensed; ask your specialty pharmacy which options are available to you.

Safety Information

Myelosuppression is a serious risk of temozolomide listed under Warnings and Precautions — it can cause low blood cell counts, including prolonged pancytopenia that has in some cases led to aplastic anemia and been fatal. Regular blood count monitoring is required during treatment. Temozolomide can also cause hepatotoxicity (liver injury); your care team will monitor liver function and watch for signs like unusual fatigue, yellowing of the skin or eyes, or dark urine. This is a chemotherapy drug prescribed and monitored by an oncology specialist — always follow your care team's specific instructions.

Sources & accuracy

This Temozolomide information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Temozolomide on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.