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Tirosint-Sol Bottle — prescription drug image

Tirosint-Sol

Tirosint-SOL 1ML of 25MCG/ML

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What is Tirosint-Sol?

Tirosint-Sol is a liquid medication used to treat hypothyroidism by providing the thyroid hormone your body needs. It's a convenient option for those who prefer a liquid form. Tirosint-Sol is available through prescription, and users can find savings cards and refill options while connecting with licensed providers via Rx.com.

Prescription savings · · · ·

What is Tirosint-Sol ?

Tirosint-Sol is a liquid medication used to treat hypothyroidism by providing the thyroid hormone your body needs. It's a convenient option for those who prefer a liquid form. Tirosint-Sol is available through prescription, and users can find savings cards and refill options while connecting with licensed providers via Rx.com.
  • Seizures or tremors
  • Fast, pounding, or uneven heartbeat
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain that may spread, trouble breathing, unusual sweating, fainting
  • Confusion, swelling of the face, tongue, or lower legs, feeling cold, unusual tiredness or weakness
  • Dizziness, lightheadedness, stomach pain
  • Severe headache, blurred or double vision, nausea, vomiting (in children)
  • Walking with a limp, knee or hip pain (in children)
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel disease, anemia, blood clotting problems, diabetes, osteoporosis, pituitary gland problems, or adrenal gland problems. Tell your doctor if you have recently received radiation treatment with iodine.
  • This medicine may cause the following problems:Heart problems, including angina (chest pain), heart rhythm problemsLow bone density
  • This medicine should not be used to treat obesity or as part of a treatment plan for a weight control program.
  • Tell any doctor or dentist who treats you that you are taking this medicine.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
What is the difference between Tirosint-Sol and regular levothyroxine?
Tirosint-SOL is a liquid (oral solution) form of levothyroxine that contains only three ingredients — levothyroxine, glycerol, and water — with no gluten, lactose, or dyes. 'Regular' levothyroxine usually refers to tablet or capsule forms, which contain additional inactive ingredients that can affect absorption in some patients. The active ingredient, synthetic T4, is the same; the formulation is what's different.
Is Tirosint-Sol the same as Synthroid?
No. Synthroid is a tablet form of levothyroxine, while Tirosint-SOL is a liquid oral solution. Both deliver the same active ingredient (synthetic levothyroxine/T4) and are used to treat hypothyroidism, but they are different dosage forms made by different companies and are not automatically interchangeable — switching between them should be supervised by your doctor with follow-up thyroid testing.
Why would a doctor prescribe Tirosint-Sol instead of levothyroxine tablets?
Some patients don't absorb tablet-form levothyroxine consistently, or react to inactive ingredients like gluten, lactose, or dyes found in some tablet formulations. Because Tirosint-SOL contains only levothyroxine, glycerol, and water, doctors sometimes prescribe it for patients with sensitivities or absorption issues. Its label also doesn't carry the proton-pump-inhibitor interaction warning that tablet labels do, and it can be taken as little as 15 minutes before breakfast, which some patients find more flexible.
Does Tirosint-Sol have a generic version?
No. There is currently no FDA-approved generic equivalent of Tirosint-SOL's oral-solution formulation. Generic levothyroxine is available, but only in tablet and capsule forms, not as this liquid solution.
How do you take Tirosint-Sol — with or without food?
Per current FDA labeling, Tirosint-SOL can be dosed as little as 15 minutes before breakfast, without the stricter food-timing restrictions that apply to some other levothyroxine products. As always, follow your own prescriber's specific instructions, since timing relative to food and other medications can affect absorption.
How much does Tirosint-Sol cost without insurance?
The price of Tirosint-Sol without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 55% off retail prices with a free Rx.com coupon.
What are the common side effects of Tirosint-Sol?
Common side effects of Tirosint-Sol may include: Seizures or tremors, Fast, pounding, or uneven heartbeat, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Chest pain that may spread, trouble breathing, unusual sweating, fainting, Confusion, swelling of the face, tongue, or lower legs, feeling cold, unusual tiredness or weakness. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Tirosint-Sol?
Generic versions may be available for Tirosint-Sol. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Tirosint-Sol on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Tirosint-Sol?
The cheapest pharmacy for Tirosint-Sol depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Tirosint-Sol near you.

Tirosint-Sol Coupons & Prices

Tirosint-SOL 1ML of 25MCG/ML

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Tirosint-Sol Bottle — prescription drug image
Prescription
Tirosint-Sol 1ml of 100mcg/ml (5)
your area ·
Prescription weight loss

Weight-loss medication, prescribed online

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$146/mo vs. brand-name GLP-1 medications $1,300+/mo Save up to 88%
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Tirosint-SOL is a liquid (oral solution) form of levothyroxine, the synthetic thyroid hormone T4, used as replacement therapy for hypothyroidism and, in certain cases, TSH suppression after thyroid cancer treatment; if you're looking for a Tirosint-SOL coupon, enter your ZIP code above to see today's price at pharmacies near you.

What Is Tirosint-SOL and How Does It Work?

Tirosint-SOL is a brand-name oral solution of levothyroxine sodium, a thyroid hormone (synthetic T4). It's FDA-approved as replacement therapy in primary, secondary, and tertiary hypothyroidism — whether congenital or acquired — in adults and children, including newborns, and as an adjunct to surgery and radioiodine therapy to suppress TSH in certain thyrotropin-dependent, well-differentiated thyroid cancers. It is not indicated for suppressing benign thyroid nodules or nontoxic goiter in patients who get enough dietary iodine, and like all levothyroxine products, it is not approved for weight loss.

What sets it apart from levothyroxine tablets and capsules is the formulation: the oral solution contains just three ingredients — levothyroxine, glycerol, and water — with no gluten, lactose, or dyes, which can matter for patients who don't absorb the pill form consistently. Its label also doesn't carry the proton-pump-inhibitor interaction warning found on tablet labels, and it can be dosed as little as 15 minutes before breakfast.

Tirosint-SOL Coupon: Manufacturer Savings Card vs. an Rx.com Cash Price

Tirosint-SOL's manufacturer runs an official patient savings program (tirosintsol.com) that can lower out-of-pocket costs for eligible patients. Like most brand savings cards, it's generally limited to people with commercial or private insurance, and eligibility, terms, and any caps can change, so check the manufacturer's site directly for current details.

If you don't have commercial insurance — you're uninsured, on Medicare, or the manufacturer card is declined at the pharmacy counter — an Rx.com cash coupon can still be used instead. Enter your ZIP code above to see today's price near you. There is currently no FDA-approved generic version of Tirosint-SOL's oral-solution formulation, so if cost is your main concern, ask your provider or pharmacist whether a levothyroxine tablet or capsule (available generically) could work for you.

Tirosint-SOL vs. Other Levothyroxine Products

Tirosint-SOL is a different dosage form from the levothyroxine capsule sold as Tirosint — same brand family, but the capsule is not the liquid solution. Other levothyroxine tablet brands include Synthroid, Levoxyl, and Unithroid, plus generic levothyroxine tablets. Armour Thyroid is a different type of thyroid replacement (desiccated natural thyroid containing both T4 and T3) rather than a levothyroxine product.

Because levothyroxine has a narrow therapeutic index, switching between any of these products should be done only under a doctor's supervision with follow-up TSH testing — they are not necessarily interchangeable dose-for-dose.

Safety Information for Tirosint-SOL

Like all levothyroxine products, Tirosint-SOL is not intended for weight loss — doses higher than what's needed to restore normal thyroid function can cause serious, even life-threatening effects, particularly when combined with certain stimulant medications used for weight reduction. It should not be used in uncorrected adrenal insufficiency or untreated thyrotoxicosis (overactive thyroid).

  • Tell your doctor if you have heart disease — levothyroxine can trigger chest pain or an irregular heartbeat, especially in older adults.
  • People with diabetes or those taking blood thinners may need dose adjustments once starting therapy.
  • Because it has a narrow therapeutic index, your doctor will check your TSH levels periodically to confirm your dose is right.

This is general information, not medical advice — talk to your provider about what's right for you.

Sources & accuracy

This Tirosint-Sol information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Tirosint-Sol on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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