What is Uvadex ?

Uvadex (methoxsalen) is a photoactive substance used in conjunction with ultraviolet (UV) light in the treatment of various skin disorders such as psoriasis, eczema, and vitiligo. When administered systemically and activated by UVA light in a therapeutic process known as extracorporeal photochemotherapy, or photopheresis, Uvadex helps regulate the immune system and reduce abnormal skin cell growth. It is specifically designed to be used in the THERAKOS Photopheresis System by medically trained professionals.

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Trouble seeing or any vision changes.

• You could get a serious sunburn while using this medicine. Carefully follow all instructions from your doctor.
• Call your doctor if your symptoms do not improve or if they get worse.
• Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away.
• Make sure your doctor knows if you are breast feeding, or if you have basal cell carcinoma (a type of skin cancer).
• Wear wrap-around sunglasses that will protect your eyes from UV light for at least 24 hours (1 day) after taking this medicine. Show your sunglasses to health caregivers. Caregivers will make sure that your sunglasses protect your eyes from UV light.
• Stay out of sunlight for at least 24 hours (1 day) after you have received this medicine. This includes avoiding sunlight that comes in from a window or when riding in a car. Also be aware that even when the sky is cloudy, the UV light can still reach your skin. If you must be in the sun, wear clothing that covers all of your skin. This includes long sleeves, a hat, and gloves. You can also apply sunscreen that has an SPF (sun protection factor) of greater than 15.