What is Xeljanz Xr ?

• Chest pain that may spread, trouble breathing, coughing up blood, unusual sweating, fainting
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Numbness or weakness in your arm or leg, or on one side of your body, pain in your lower leg
• Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
• Stomach pain, cramping, bloody stools
• Sudden or severe headache, problems with vision, speech, or walking
• Skin or mole changes, sores that do not heal
• Fever, chills, cough, runny or stuffy nose, sore throat, night sweats, body aches
• Change in how much or how often you urinate, difficult or painful urination
• Pain, redness, swelling, or tenderness in the arms or legs
• Unusual bleeding, bruising, or weakness
• Swollen glands in your neck, armpits, or groin

• Keep all medicine out of the reach of children. Never share your medicine with anyone.
• It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control during treatment with this medicine.
• Do not breastfeed during treatment with this medicine and for at least 18 hours after the last dose of Xeljanz® tablet or 36 hours after the last dose of Xeljanz® XR.
• Tell your doctor if you have kidney disease (including patients on dialysis), liver disease (including hepatitis B or C), lung disease (including interstitial lung disease), heart or blood vessel disease, HIV, cancer or a history of cancer, blood problems, diabetes, high cholesterol, stomach or bowel problems (including blockage, diverticulitis, ulcers), or a history of tuberculosis. Tell your doctor if you have a current infection or an infection that keeps coming back, or if you are a current or past smoker.
• This medicine may cause the following problems:Increased risk of serious infections (bacterial, fungal, viral), including herpes infection or shinglesIncreased risk of certain cancers (including lymphoma, lung cancer, skin cancer)Increased risk of blood clots (including arterial thrombosis, deep vein thrombosis, pulmonary embolism), especially in patients with rheumatoid arthritis who are 50 years of age and older and with a heart or blood vessel diseaseIncreased risk of serious heart or blood vessel disease (including heart attack, stroke)Stomach or bowel perforation (tear or hole)High cholesterol in the blood
• You will need to have a skin test for tuberculosis (TB) before you start this medicine. Tell your doctor if you or anyone in your home has ever had a positive TB skin test or been exposed to TB.
• Talk with your doctor before using this medicine if you plan to have children. Some women who use this medicine have become infertile (unable to have children).
• This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.