Monthly vs 12-Month GLP-1 Plans: Which Saves More This Black Friday?
A 12-month plan has the lowest monthly cost, and a 1-month plan has the lowest starting cost. Here is how the numbers compare with code BF2026, and how to pick the one that fits your situation.
The 12-month plan saves the most per month, but only if you stay on treatment for the full year. With code BF2026 (now through December 1, 2026), Rx.com's compounded semaglutide works out to $79.20 a month on a 12-month plan paid up front ($950.40) versus $140 for a single month. For tirzepatide, it is $119.20 a month on 12 months ($1,430.40) versus $228 for one month.
- Code BF2026 takes 20% off every plan length, now through December 1, 2026.
- Every plan is paid once, up front, for its full length.
- Longer plans cost less per month but more at checkout.
- One flat price at every dose, on every plan.
- No plan auto-renews, and nothing is charged until a provider approves you.
- On the 12-month plan, medication ships every 3 months.
Semaglutide plans side by side
Here is every compounded semaglutide plan at Rx.com, at the regular price and with code BF2026 now through December 1, 2026.
| Plan | Regular, paid up front | With BF2026, paid up front | Sale per month |
|---|---|---|---|
| 1 month | $175 | $140 | $140 |
| 3 months | $495 | $396 | $132 |
| 6 months | $875 | $700 | about $117 |
| 12 months | $1,188 | $950.40 | $79.20 |
Tirzepatide plans side by side
Compounded tirzepatide follows the same pattern at a higher price point.
| Plan | Regular, paid up front | With BF2026, paid up front | Sale per month |
|---|---|---|---|
| 1 month | $285 | $228 | $228 |
| 3 months | $795 | $636 | $212 |
| 6 months | $1,550 | $1,240 | about $207 |
| 12 months | $1,788 | $1,430.40 | $119.20 |
Not sure which medicine fits you? Our guide to semaglutide vs tirzepatide explains how they differ. Your provider makes the final call.
How much each plan saves over a year
A fair way to compare is to ask what a full year of treatment would cost if you bought it in each plan size. This assumes you buy the same plan again each time it ends, at the sale price. In reality, the BF2026 code only applies to purchases made now through December 1, 2026, so repeat purchases later would likely be at regular prices.
| Semaglutide plan | Year of treatment at sale price | Year of treatment at regular price |
|---|---|---|
| 1 month x 12 | $1,680 | $2,100 |
| 3 months x 4 | $1,584 | $1,980 |
| 6 months x 2 | $1,400 | $1,750 |
| 12 months x 1 | $950.40 | $1,188 |
The gap is large. A year on the 12-month semaglutide plan at the sale price costs about $730 less than buying 1 month at a time at the sale price. Only one plan locks the whole year in at the sale price, though: the 12-month plan bought during the sale window.
The tradeoffs of a longer plan
Saving money is only half the picture. A longer plan also means:
- A bigger payment up front. $950.40 for semaglutide or $1,430.40 for tirzepatide, all at once.
- Less flexibility. If side effects are hard to live with, or your provider decides the medicine is not right for you, you have already paid for months you may not use. Ask about the refund terms before you buy, because we do not cover them here.
- A longer commitment to one medicine. If you think you might want to switch between semaglutide and tirzepatide, a shorter plan keeps that easier.
On the plus side, a longer plan means fewer reorders, one flat price even as your dose climbs, and medication that ships every 3 months on the 12-month plan.
💡 Side effects are most common early
Nausea, diarrhea, constipation and stomach pain are the most common side effects of semaglutide, and they tend to show up when the dose is raised. Many people find they ease with time. If you have never taken a GLP-1, a short first plan can help you learn how your body responds. Our guide on what to expect in the first 30 days covers this.
How to choose
Which plan length fits you?
A quick guide, not medical advice:
12 months may fit if
- You have taken a GLP-1 before and tolerated it
- You plan to stay on treatment for a year
- You can pay the full amount up front comfortably
A shorter plan may fit if
- This is your first GLP-1
- You are unsure between semaglutide and tirzepatide
- A large single payment would strain your budget
The 3-month and 6-month plans sit in the middle. With BF2026, 3 months of semaglutide is $396 and 6 months is $700, both well below the 1-month rate per month.
When another option may cost less
Before choosing any plan, check whether you qualify for something cheaper. If your commercial insurance covers a GLP-1 for weight management, a manufacturer savings card may bring your copay to $25 a month. If you have Medicare Part D, the Medicare GLP-1 Bridge sets a $50 copay on certain GLP-1 drugs for eligible members from July 1, 2026 through December 31, 2027. Those routes can beat any self-pay price, and we would rather you use them if you can.
Getting treatment through Rx.com
Rx.com offers compounded semaglutide from $99/month and compounded tirzepatide from $149/month on a 12-month plan, with an online provider visit, medication, supplies and cold shipping included. With code BF2026 now through December 1, 2026, those become $79.20 and $119.20 a month on the 12-month plan. It is one flat price at every dose, and no insurance is needed.
Compounded medications are not FDA-approved. A licensed provider reviews your health history to decide whether treatment is right for you, and nothing is charged until you are approved. Plans do not auto-renew. Treatment is not available in Alaska, Louisiana or Mississippi. Start with our weight-loss check, or see how to use code BF2026.
🚨 When to Contact Your Healthcare Provider
Call your provider right away if any of these happen. Call 911 for trouble breathing, fainting or severe pain.
- Severe belly pain that will not go away, with or without vomiting, especially if it spreads to your back: possible pancreatitis.
- Pain in the upper right belly, fever, or yellow skin or eyes: possible gallbladder problem.
- Vomiting or diarrhea that keeps you from drinking fluids: risk of dehydration and kidney injury.
- Swelling of the face, lips or throat, hives or trouble swallowing: possible allergic reaction.
- A lump in the neck, hoarseness or trouble swallowing: tell your provider promptly.
Frequently Asked Questions
Is the 12-month GLP-1 plan worth it?
It has the lowest monthly cost, $79.20 for semaglutide with code BF2026, but you pay $950.40 up front. It suits people who already plan to stay on treatment for a year.
Does BF2026 work on the monthly plan?
Yes. It takes 20% off every plan length, so 1 month of semaglutide is $140 and 1 month of tirzepatide is $228, now through December 1, 2026.
Am I billed monthly on the 12-month plan?
No. You pay once at the start. Medication ships every 3 months, with no monthly charges.
Do plans renew automatically?
No. Rx.com plans do not auto-renew.
Will I pay more if my dose goes up?
No. Every plan is one flat price at every dose your provider prescribes.
Can I buy a shorter plan now and a longer one later?
Yes, but the BF2026 code only applies to orders placed now through December 1, 2026. Later purchases would be at the price in effect at that time.
Is compounded semaglutide FDA-approved?
No. Compounded medications are not FDA-approved and are not the same as any brand-name medication.
Sources
- MedlinePlus. Semaglutide injection. medlineplus.gov
- Centers for Medicare & Medicaid Services. Medicare GLP-1 Bridge. cms.gov
- Novo Nordisk. NovoCare savings offer and self-pay pricing. novocare.com
- U.S. Food and Drug Administration. FDA's concerns with unapproved GLP-1 drugs used for weight loss. fda.gov
