Monthly vs 6-Month vs 12-Month GLP-1 Plans: Which Saves More This Black Friday?
The Black Friday sale covers the 6-month plan (6 months for the price of 3) and the 1-month plan. Here is how they compare with each other and with buying a full year, and how to pick the length that fits you.
Right now the 6-month plan is the best value per month by a wide margin. Through Tuesday, December 1, 2026, Rx.com's compounded semaglutide is $495 for 6 months (about $82.50 a month) versus $139 for a single month on sale or $1,188 for 12 months at the regular price. For tirzepatide, it is $795 for 6 months (about $132.50 a month) versus $249 for one month on sale or $1,788 for 12 months. The 3 and 12-month plans stay at regular prices.
- The Black Friday deal is "buy 3 months, get 3 months free" on the 6-month plan, plus a lower 1-month price ($139 / $249).
- Sale dates: now through December 1, 2026, 11:59 pm Central. No code needed.
- Every plan is paid once, up front, for its full length.
- Same price at every dose, on every plan.
- No plan auto-renews, and you are charged only if a provider prescribes.
- If you are sure you want a full year, the regular 12-month plan on our semaglutide or tirzepatide page can still cost less in total.
Semaglutide plans side by side
Here is every compounded semaglutide plan at Rx.com, with Black Friday prices on the 1-month and 6-month plans now through December 1, 2026. The 3 and 12-month plans are sold at regular prices on our semaglutide page.
| Plan | Regular, paid up front | During the sale, paid up front | Works out to per month |
|---|---|---|---|
| 1 month | $175 | $139 (save $36) | $139 |
| 3 months | $495 | $495 (no sale) | $165 |
| 6 months | $875 | $495 (save $380) | $495 for 6 months, about $82.50 a month |
| 12 months | $1,188 | $1,188 (no sale) | $99 |
Tirzepatide plans side by side
Compounded tirzepatide follows the same pattern at a higher price point. Its 3 and 12-month plans are on our tirzepatide page.
| Plan | Regular, paid up front | During the sale, paid up front | Works out to per month |
|---|---|---|---|
| 1 month | $285 | $249 (save $36) | $249 |
| 3 months | $795 | $795 (no sale) | $265 |
| 6 months | $1,550 | $795 (save $755) | $795 for 6 months, about $132.50 a month |
| 12 months | $1,788 | $1,788 (no sale) | $149 |
Not sure which medicine fits you? Our guide to semaglutide vs tirzepatide explains how they differ. Your provider makes the final call.
What a year of treatment costs each way
A fair way to compare is to ask what a full year would cost. The sale price only applies to orders placed now through December 1, 2026, so this assumes any later purchase is at the regular price.
| A year of treatment | Semaglutide | Tirzepatide |
|---|---|---|
| 1 month x 12 (first month at the Black Friday price, then regular) | $2,064 | $3,384 |
| 3 months x 4, regular | $1,980 | $3,180 |
| Black Friday 6 months, then 6 months at regular price | $1,370 | $2,345 |
| 12 months x 1, regular | $1,188 | $1,788 |
Two honest takeaways. First, for the next 6 months nothing comes close to the sale plan: $495 covers 6 months of semaglutide, while 6 months on the 12-month plan's average would be $594. Second, if you are certain you want a full year, the regular 12-month plan (on our semaglutide and tirzepatide pages) costs $182 less for semaglutide and $557 less for tirzepatide than the sale plan plus a second 6 months. The sale plan wins if you might stop, switch medicines or take a break before the year is up.
The tradeoffs of a longer plan
Saving money is only half the picture. A longer plan also means:
- A bigger payment up front. $495 for 6 months of semaglutide on sale, or $1,188 for 12 months at the regular price.
- Less flexibility. If side effects are hard to live with, or your provider decides the medicine is not right for you, you have already paid for months you may not use. Ask about the refund terms before you buy, because we do not cover them here.
- A longer commitment to one medicine. If you think you might want to switch between semaglutide and tirzepatide, a shorter plan keeps that easier.
On the plus side, a longer plan means fewer reorders and the same price even as your dose climbs. Every plan includes free express shipping in plain packaging, care team messaging and check-ins before refills.
💡 Side effects are most common early
Nausea, diarrhea, constipation and stomach pain are the most common side effects of semaglutide, and they tend to show up when the dose is raised. Many people find they ease with time. If you have never taken a GLP-1, a 1-month plan can help you learn how your body responds. During the sale it is $139 for semaglutide or $249 for tirzepatide, though it costs more per month than the 6-month plan. Our guide on what to expect in the first 30 days covers this.
How to choose
Which plan length fits you?
A quick guide, not medical advice:
The Black Friday 6-month plan may fit if
- You plan to stay on treatment for at least 6 months
- You want the lowest cost per month right now
- You can order by December 1, 2026
Another plan may fit if
- This is your first GLP-1 and you want a small first payment (1 month, $139 or $249 on sale)
- You are sure you want a full year (regular 12 months on the semaglutide or tirzepatide page)
- A single payment would strain your budget
The 3-month plan is not part of the sale. It sits in the middle at regular prices, $495 for semaglutide or $795 for tirzepatide, which is more than the 6-month sale plan, so it rarely makes sense right now.
When another option may cost less
Before choosing any plan, check whether you qualify for something cheaper. If your commercial insurance covers a GLP-1 for weight management, a manufacturer savings card may bring your copay to $25 a month. If you have Medicare Part D, the Medicare GLP-1 Bridge sets a $50 copay on certain GLP-1 drugs for eligible members from July 1, 2026 through December 31, 2027. Those routes can beat any self-pay price, and we would rather you use them if you can.
Getting treatment through Rx.com
During the Black Friday sale, Rx.com's compounded semaglutide is $495 for 6 months (about $82.50 a month) and compounded tirzepatide is $795 for 6 months (about $132.50 a month), with the provider review, medication, supplies and free express shipping included. It is the same price at every dose, there is no membership fee, and no insurance is needed. The sale ends December 1, 2026.
Compounded medications are not FDA-approved. A licensed provider reviews your health history to decide whether treatment is right for you, and you are charged only if a provider prescribes. Plans do not auto-renew. Treatment is not available in Alaska, Louisiana or Mississippi. There is no code to enter: see if you qualify, and the Black Friday price is applied at checkout. Our guide to what's included in the $495 plan has the details.
🚨 When to Contact Your Healthcare Provider
Call your provider right away if any of these happen. Call 911 for trouble breathing, fainting or severe pain.
- Severe belly pain that will not go away, with or without vomiting, especially if it spreads to your back: possible pancreatitis.
- Pain in the upper right belly, fever, or yellow skin or eyes: possible gallbladder problem.
- Vomiting or diarrhea that keeps you from drinking fluids: risk of dehydration and kidney injury.
- Swelling of the face, lips or throat, hives or trouble swallowing: possible allergic reaction.
- A lump in the neck, hoarseness or trouble swallowing: tell your provider promptly.
Frequently Asked Questions
Is the 12-month GLP-1 plan worth it during Black Friday?
It is not on sale. It averages $99 a month for semaglutide ($1,188 up front). The Black Friday 6-month plan is $495 for 6 months, about $82.50 a month, but if you are sure you want a full year, the regular 12-month plan on our semaglutide page can cost less overall.
Is the monthly plan on sale?
Yes. Through December 1, 2026, one month of semaglutide is $139 (regularly $175) and one month of tirzepatide is $249 (regularly $285). The 6-month plan is still the better value per month.
Am I billed monthly on the 6-month plan?
No. You pay once at the start, with no monthly charges.
Do plans renew automatically?
No. Rx.com plans do not auto-renew.
Will I pay more if my dose goes up?
No. Every plan is the same price at every dose your provider prescribes.
Can I buy the sale plan now and a longer one later?
Yes, but the Black Friday price only applies to orders placed now through December 1, 2026. Later purchases would be at the price in effect at that time.
Is compounded semaglutide FDA-approved?
No. Compounded medications are not FDA-approved and are not the same as any brand-name medication.
Sources
- MedlinePlus. Semaglutide injection. medlineplus.gov
- Centers for Medicare & Medicaid Services. Medicare GLP-1 Bridge. cms.gov
- Novo Nordisk. NovoCare savings offer and self-pay pricing. novocare.com
- U.S. Food and Drug Administration. FDA's concerns with unapproved GLP-1 drugs used for weight loss. fda.gov
