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Atomoxetine Hcl (Strattera)

Atomoxetine HCl 40MG

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What is Atomoxetine Hcl?

Atomoxetine HCl, marketed under the brand name Strattera, is a selective norepinephrine reuptake inhibitor (NRI) primarily used to treat attention deficit hyperactivity disorder (ADHD) in children, adolescents, and adults. Unlike stimulant medications, it is not classified as a controlled substance, offering a non-addictive treatment alternative. Atomoxetine works by increasing norepinephrine levels in the brain, which helps to decrease impulsivity and hyperactivity while enhancing attention span.

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What is Atomoxetine Hcl ?

Atomoxetine HCl, marketed under the brand name Strattera, is a selective norepinephrine reuptake inhibitor (NRI) primarily used to treat attention deficit hyperactivity disorder (ADHD) in children, adolescents, and adults. Unlike stimulant medications, it is not classified as a controlled substance, offering a non-addictive treatment alternative. Atomoxetine works by increasing norepinephrine levels in the brain, which helps to decrease impulsivity and hyperactivity while enhancing attention span.
  • Sudden or severe headache, problems with vision, speech, or walking
  • Fast, slow, pounding, or uneven heartbeat
  • Painful, prolonged erection of the penis
  • Extreme energy, mood or mental changes, confusion, anxiety, agitation, restlessness, trouble sleeping, unusual thoughts or behavior
  • Slow growth in children
  • Numbness or weakness in your arm or leg, or on one side of your body, pain in your lower leg
  • Lightheadedness, dizziness, fainting
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate
  • Chest pain that may spread, trouble breathing, coughing up blood, unusual sweating
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel disease, heart rhythm problems, high or low blood pressure, or problems with urination. Tell your doctor if you or anyone in your family has a history of depression, bipolar disorder, suicide, or mental illness.
  • For some children, teenagers, and young adults, this medicine may increase mental or emotional problems. This may lead to thoughts of suicide and violence. Talk with your doctor right away if you have any thoughts or behavior changes that concern you. Tell your doctor if you or anyone in your family has a history of bipolar disorder or suicide attempts.
  • This medicine may cause the following: Liver problemsHeart or blood vessel problemsBlood pressure changesPainful or prolonged erection of the penisSlowed growth in children
  • This medicine may make you dizzy or drowsy. Do not drive or doing anything that could be dangerous until you know how this medicine affects you.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Headache, lightheadedness, dizziness, fainting
  • Mood changes, aggressiveness, irritability, depression
  • Seeing, hearing, or feeling things that are not there, believing things that are not true
  • Seizures or tremors
  • Thoughts or plans of suicide
  • Weight changes, slowed growth (children)
Is atomoxetine a stimulant or a controlled substance?
No. Atomoxetine is a non-stimulant ADHD medication classified as a selective norepinephrine reuptake inhibitor (NRI). It is not a controlled substance, which is one reason it is often chosen for people who prefer to avoid stimulants or who have a history of substance use.
How long does atomoxetine take to start working for ADHD?
Unlike stimulants, atomoxetine does not work right away. It is taken every day and builds its effect gradually. Some people notice early improvement within a couple of weeks, but it can take several weeks of consistent daily use to see the full benefit. Keep taking it as prescribed and talk with your provider about your progress.
What is the difference between atomoxetine and Strattera?
There is no difference in the active ingredient. Strattera is the brand name, and atomoxetine is the generic version. Both contain atomoxetine hydrochloride and are FDA-approved to treat ADHD. The generic typically costs much less than the brand.
What are the most common side effects of atomoxetine?
The most common side effects include decreased appetite, nausea, vomiting, dry mouth, tiredness, trouble sleeping, dizziness, and sexual side effects. Most are mild, but contact your provider if side effects are severe or do not go away, and seek care right away for signs of liver problems or mood changes.
Can atomoxetine be taken with other ADHD or antidepressant medications?
Sometimes, but only under a provider's guidance. Atomoxetine must not be used with MAO inhibitor antidepressants (or within 14 days of stopping one). It can interact with certain other medications, so always give your doctor and pharmacist a full list of everything you take before combining atomoxetine with another ADHD drug or antidepressant.
How much does Atomoxetine Hcl cost without insurance?
The price of Atomoxetine Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 94% off retail prices with a free Rx.com coupon.
What are the common side effects of Atomoxetine Hcl?
Common side effects of Atomoxetine Hcl may include: Sudden or severe headache, problems with vision, speech, or walking, Fast, slow, pounding, or uneven heartbeat, Painful, prolonged erection of the penis, Extreme energy, mood or mental changes, confusion, anxiety, agitation, restlessness, trouble sleeping, unusual thoughts or behavior, Slow growth in children. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Atomoxetine Hcl?
Generic versions may be available for Atomoxetine Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Atomoxetine Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Atomoxetine Hcl?
The cheapest pharmacy for Atomoxetine Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Atomoxetine Hcl near you.

Atomoxetine Hcl (Strattera) Coupons & Prices

Atomoxetine HCl 40MG

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Atomoxetine Hcl Capsule — prescription drug image
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Looking for an atomoxetine HCl coupon? Atomoxetine hydrochloride is the FDA-approved generic version of Strattera, a non-stimulant medication used to treat attention-deficit/hyperactivity disorder (ADHD) in adults and children 6 years and older. Because it is a generic, atomoxetine is already far more affordable than the brand, but the cash price still varies widely from one pharmacy to the next. With a free Rx.com discount coupon you can compare atomoxetine prices across more than 60,000 pharmacies and pay the lowest cash price near you. Enter your ZIP above to see today's price at pharmacies in your area.

What is atomoxetine and how does it work?

Atomoxetine is a selective norepinephrine reuptake inhibitor (NRI) and is classified as a non-stimulant ADHD medication. Rather than acting like a stimulant, it works by increasing the amount of norepinephrine, a natural chemical in the brain that helps with attention and impulse control. It is FDA-approved to treat ADHD in adults and children 6 years and older as part of a total treatment program that may also include counseling or other support.

Because it is not a stimulant or a controlled substance, atomoxetine is often chosen for people who do not tolerate or prefer to avoid stimulants, or who have a history of substance use. Unlike stimulants that can work the same day, atomoxetine is taken every day and builds its effect over several weeks.

How much does atomoxetine cost without insurance?

Atomoxetine is available as an FDA-approved generic, so it typically costs much less than brand-name Strattera. Even so, the cash price you pay can differ a lot depending on which pharmacy you use, your dose (atomoxetine comes in several capsule strengths), and your location. That is exactly why comparing prices matters.

Rx.com compares the cash price of atomoxetine at more than 60,000 pharmacies nationwide so you can find the lowest price near you. Our discount coupons are free to use, work even if you do not have insurance, and can sometimes beat an insurance copay. Enter your ZIP above to see today's price and print or text yourself a coupon.

Atomoxetine alternatives and related ADHD medications

Atomoxetine is one of several options for treating ADHD. Its brand-name equivalent is Strattera, which contains the same active ingredient. Other non-stimulant medications your provider might consider include guanfacine, clonidine, and viloxazine (sold under the brand Qelbree). Stimulant options such as methylphenidate are also commonly used.

The right choice depends on your medical history, other conditions, and how you respond to treatment, so this decision should always be made with your prescriber. If you and your provider settle on atomoxetine, you can compare prices for it and any of these alternatives using Rx.com before you fill your prescription.

Atomoxetine safety and side effects

Atomoxetine carries a boxed warning, the FDA's most serious warning, for an increased risk of suicidal thoughts in children and adolescents. Anyone starting the medication, especially young patients, should be watched closely for worsening mood, unusual changes in behavior, or thoughts of self-harm, particularly when treatment begins or the dose changes. Other serious but less common risks include severe liver injury (stop the medicine and call your provider if you notice yellowing of the skin or eyes), increases in blood pressure and heart rate, heart-related events in people with existing structural heart problems, new or worsening psychiatric symptoms, prolonged or painful erections (priapism), and allergic reactions.

Atomoxetine should not be used with MAO inhibitors (or within 14 days of stopping one), or by people with narrow-angle glaucoma, pheochromocytoma, or serious cardiovascular disorders. The most common side effects include decreased appetite, nausea, vomiting, dry mouth, tiredness, trouble sleeping, dizziness, and sexual side effects. This information is not medical advice; talk with your doctor or pharmacist about your full medical history and any other medicines you take before starting atomoxetine.

Sources & accuracy

This Atomoxetine Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Atomoxetine Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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