Azelastine-Fluticasone Coupons & Prices

If you have been handed a prescription for azelastine and fluticasone propionate nasal spray, an azelastine-fluticasone coupon from Rx.com can lower what you pay at the pharmacy counter, whether or not you have insurance. This is the generic version of the two-in-one allergy spray sold under the brand name Dymista, and it delivers 137 mcg of azelastine hydrochloride and 50 mcg of fluticasone propionate in each spray. Generic versions are made by more than one manufacturer, and supply has been uneven at some pharmacies, so a bottle that is in stock at one counter may not be at another. Cash prices for the same bottle can also differ a great deal from pharmacy to pharmacy, so it pays to compare. Enter your ZIP code above to see today's price at pharmacies near you and print, text, or email a free coupon.

What is azelastine-fluticasone nasal spray and how does it work?

Azelastine hydrochloride and fluticasone propionate nasal spray is a fixed-dose combination that puts two different allergy medicines into a single bottle. Azelastine is an H1 antihistamine, which blocks the histamine your body releases during an allergic reaction, so it works quickly on sneezing, itching, and runny nose. Fluticasone propionate is an intranasal corticosteroid, which calms the underlying inflammation in the lining of the nose and works especially well on congestion and stuffiness. Together they cover more symptoms than either ingredient covers alone.

It is FDA-approved for the relief of the symptoms of seasonal allergic rhinitis (such as sneezing, runny nose, itchy nose, and nasal congestion) in adults and children 6 years of age and older. The recommended dosage on the label is 1 spray (137 mcg azelastine hydrochloride / 50 mcg fluticasone propionate) in each nostril twice daily. It is a prescription product and is not a controlled substance. Follow the directions your prescriber and pharmacist give you.

What azelastine-fluticasone costs without insurance, and how to pay less

Most pharmacies fill this prescription with the generic azelastine hydrochloride/fluticasone propionate nasal spray rather than the brand. "Generic" does not automatically mean "cheap" at every counter, though. Cash prices for the identical bottle can swing widely between a big chain, a grocery-store pharmacy, and an independent down the street, because each one sets its own cash price. Supply from generic manufacturers has also been uneven, which can affect both stock and price at your local pharmacy. The only way to know what you would actually pay is to compare, and to check again at each refill.

Rx.com compares prices at more than 60,000 pharmacies nationwide and shows you a free discount coupon you can use even if you have no insurance, or if your plan does not cover this combination spray. It is worth checking the coupon price against your copay, since the coupon price is sometimes the lower of the two. If your prescriber writes for the brand, ask whether a manufacturer copay or savings program applies to you, since coupon programs and manufacturer programs cannot be combined. Enter your ZIP code above to see today's price near you.

Alternatives and how it compares

Which allergy medicine is right for you is a decision for you and your prescriber, but these are the products people most often compare with azelastine-fluticasone:

• Flonase and generic fluticasone propionate — a steroid nasal spray alone, available over the counter. The combination spray is often prescribed when a steroid spray by itself is not controlling symptoms; it carries the same corticosteroid cautions plus the antihistamine's drowsiness risk.
• Azelastine — the antihistamine nasal spray by itself, without the steroid. It can still cause a bitter taste and drowsiness.
• Ryaltris — a different prescription antihistamine-plus-steroid nasal spray combination (olopatadine and mometasone).
• Cetirizine — an oral antihistamine tablet, a different route with different side effects, including drowsiness in some people.
• Montelukast — an oral prescription tablet used for allergic rhinitis and asthma that works on a different pathway (leukotrienes). It carries an FDA boxed warning for serious neuropsychiatric events, including mood and behavior changes and suicidal thoughts, and the FDA advises reserving it for allergic rhinitis when other treatments are not tolerated or effective. Discuss that risk with your prescriber before starting it.

A nasal spray delivers medicine straight to the nose, while a tablet works through the bloodstream. Some people do better on one, some on a combination. Do not add or swap allergy medicines on your own, and tell your provider everything you are already taking.

Safety, side effects, and what to tell your provider

This nasal spray has no boxed warning. According to the prescribing information, the most common adverse reactions (occurring in 2% or more of patients) are dysgeusia (an unpleasant, bitter, or altered taste, the most frequently reported reaction), epistaxis (nosebleed), and headache. The bitter taste is often reduced by keeping your head tilted forward and not sniffing hard after each spray. Other local effects can include nasal ulceration, a Candida (yeast) infection in the nose, and impaired wound healing, so the spray should be avoided if you have had recent nasal surgery, nasal trauma, or nasal ulcers; nasal septal perforation has been reported. Because the azelastine component can cause drowsiness (somnolence), do not drive or do anything hazardous until you know how the spray affects you, and avoid alcohol and other central nervous system depressants, which can add to it.

With prolonged use, the fluticasone component carries the usual corticosteroid class risks: glaucoma and cataracts (tell your provider about vision changes or a history of raised eye pressure), signs of too much steroid in the body or adrenal suppression (more of a concern if you also take a systemic or inhaled corticosteroid), and slowed growth velocity in children, whose height should be monitored routinely. Steroids can also increase susceptibility to infection, so use with caution if you have an untreated fungal, bacterial, or viral infection or ocular herpes simplex, and let your provider know about any chickenpox or measles exposure if you are not immune. Strong CYP3A4 inhibitors such as ritonavir and ketoconazole raise fluticasone levels in the body and can cause systemic corticosteroid effects; use with ritonavir is not recommended. Hypersensitivity reactions, including anaphylaxis, have been reported. This page is information, not medical advice, and it is not a complete list of side effects. Talk with your doctor or pharmacist about your own situation and report anything that worries you.