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Azelastine Hcl Bottle Of Nasal Spray — prescription drug image

Azelastine Hcl

Azelastine HCl 30ML of 137MCG/SPRAY

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What is Azelastine Hcl?

Azelastine HCl is an antihistamine nasal spray used primarily for the treatment of allergic rhinitis. It works by blocking histamine receptors to reduce nasal inflammation, itching, and congestion. This medication provides relief from symptoms caused by environmental allergens, typically presenting effects within minutes of application.

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What is Azelastine Hcl ?

Azelastine HCl is an antihistamine nasal spray used primarily for the treatment of allergic rhinitis. It works by blocking histamine receptors to reduce nasal inflammation, itching, and congestion. This medication provides relief from symptoms caused by environmental allergens, typically presenting effects within minutes of application.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Burning, redness, swelling, or irritation around or inside your nose
  • Heavy nosebleeds
  • Fever, chills, cough, sore throat, body aches
  • Tell your doctor you are pregnant or breastfeeding, or if you have kidney disease or any other nose problems (including ulcers or surgery, or injury that has not healed).
  • This medicine may make you drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is azelastine HCl nasal spray used for?
The 0.1% nasal spray treats symptoms of seasonal allergic rhinitis, such as sneezing, runny nose, itchy nose, and nasal congestion, in adults and children 5 years and older. It also treats symptoms of vasomotor (nonallergic) rhinitis in adults and adolescents 12 years and older. The 0.15% strength is used for seasonal allergic rhinitis in patients 6 years and older and perennial allergic rhinitis in patients 6 years and older. Azelastine is also made as a 0.05% eye drop for itching from allergic conjunctivitis.
Does azelastine nasal spray make you sleepy?
It can. Even though you spray it in your nose rather than swallow it, drowsiness is a known effect. Do not drive or operate machinery until you know how azelastine affects you, and avoid alcohol, sedatives, and other medicines that cause drowsiness, because they increase the sedation. Tell your clinician if the sleepiness is a problem for you.
Is azelastine the same as Astepro or Astelin?
Azelastine hydrochloride is the active ingredient. Astepro and Astepro Allergy are nasal brands of azelastine, and Astepro Allergy is now sold over the counter for adults and children 6 and older. Astelin, the older nasal brand, and Optivar, the eye-drop brand, are no longer marketed. Azelastine is also one of the two ingredients in Dymista, which combines azelastine with fluticasone propionate.
How long does it take for azelastine nasal spray to work?
This varies from person to person, and the details of how quickly you should expect relief are best answered by your clinician or pharmacist based on your product's labeling. Use it exactly as directed and let your clinician know if your symptoms are not improving. Do not increase your dose on your own.
Can you use azelastine and fluticasone (Flonase) together?
The two are used together often enough that a combination product exists: Dymista contains both azelastine and fluticasone propionate in one spray. That said, whether you should use both, and how, is a decision for your clinician, who can look at your symptoms and the rest of your medicines. Do not add a second nasal spray on your own without asking.
How much does Azelastine Hcl cost without insurance?
The price of Azelastine Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Azelastine Hcl?
Common side effects of Azelastine Hcl may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Burning, redness, swelling, or irritation around or inside your nose, Heavy nosebleeds, Fever, chills, cough, sore throat, body aches. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Azelastine Hcl?
Generic versions may be available for Azelastine Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Azelastine Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Azelastine Hcl?
The cheapest pharmacy for Azelastine Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Azelastine Hcl near you.

Azelastine Hcl Coupons & Prices

Azelastine HCl 30ML of 137MCG/SPRAY

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Azelastine Hcl Bottle Of Nasal Spray — prescription drug image
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Azelastine Hcl 30ml of 0.1% (137mcg/spray) (1)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Use a free Rx.com azelastine HCl coupon to compare cash prices for azelastine hydrochloride nasal spray and eye drops at more than 60,000 pharmacies near you. Azelastine is a prescription antihistamine used for allergy symptoms in the nose and itching of the eyes, and it is available as a generic. Cash prices for the same prescription can differ a lot from one pharmacy to the next, even across the street, so it is worth checking before you fill. Enter your ZIP above to see today's price at pharmacies near you.

What is azelastine HCl and how does it work?

Azelastine hydrochloride is a second-generation H1-receptor antagonist, better known as an antihistamine. It also helps stabilize mast cells and has anti-inflammatory activity. Instead of being swallowed as a pill, it is applied right where the symptoms are: as a spray inside the nose, or as drops in the eyes.

What each form treats depends on the product and strength:

  • Nasal spray 0.1%: symptoms of seasonal allergic rhinitis in adults and children 5 years and older, and symptoms of vasomotor (nonallergic) rhinitis in adults and adolescents 12 years and older. Those are the only two indications on the 0.1% labeling; perennial allergic rhinitis is not one of them.
  • Nasal spray 0.15%: seasonal allergic rhinitis in patients 6 years and older, and perennial allergic rhinitis in patients 6 years and older.
  • Ophthalmic solution 0.05%: relief of eye itching associated with allergic conjunctivitis, one drop in each affected eye twice daily.

Azelastine cost without insurance, and why comparing pharmacies matters

Azelastine hydrochloride is available as a generic, and generics are filled under the same FDA standards as the brand. That does not mean every pharmacy charges the same. Cash prices are set pharmacy by pharmacy and can vary widely in a single ZIP code, which is exactly why comparing is worth the two minutes it takes. There is no manufacturer savings card for generic azelastine.

An Rx.com coupon is free and is meant for people paying cash, or for anyone whose insurance price is higher than the discounted cash price. You can also ask your pharmacist to run both and use whichever is lower. Worth knowing honestly: an over-the-counter version of the nasal spray, Astepro Allergy, is sold without a prescription for adults and children 6 and older, so if that fits your situation the shelf price may be the simpler path. Enter your ZIP above to see today's price near you.

Azelastine vs. other allergy options

Azelastine is one of several approaches to allergy symptoms, and the right one depends on your symptoms and what your clinician recommends. Some comparisons people ask about:

Prices differ between all of these, so if your clinician says more than one option would work for you, comparing prices on each is reasonable. Enter your ZIP above to check.

Safety and side effects to know

Azelastine has no boxed warning. The most important thing to know is that drowsiness can happen even though the medicine goes in your nose or eyes. Do not drive or operate machinery until you know how it affects you, and avoid alcohol, sedatives, and other medicines that slow you down, since they add to the sedation. A bitter or unpleasant taste is the most common complaint with the nasal spray; tilting your head forward and breathing gently while you spray helps. Other reported effects include headache, nasal burning or discomfort, sneezing, nosebleed, sore throat, dry mouth, dizziness, nausea, and tiredness. With the eye drops, people may notice brief burning or stinging, a bitter taste, and headache.

Do not use the spray in a nose that has had recent surgery, an injury, or open sores. Do not spray it into your eyes and do not swallow it. If you wear contact lenses, take them out before using the eye drops and wait 10 minutes before putting them back in; the drops are not for contact-lens-related irritation. Do not share your bottle with anyone else. Talk with your clinician about use during pregnancy or breastfeeding. This information is not medical advice, so please go over your full medicine list with your doctor or pharmacist.

Sources & accuracy

This Azelastine Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Azelastine Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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