Cetirizine Hcl
Cetirizine HCl
What is Cetirizine Hcl?
If you are diagnosed with hay fever or allergies, your doctor might prescribe cetirizine. The drug is also used to treat urticaria (hives) which is an allergic skin reaction.
Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Skin or whites of your eyes turn yellow.
Warnings
- This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
- Talk with your doctor before taking this medicine if you are pregnant or breast feeding.
- Check with your doctor before using this medicine if you have kidney disease or liver disease.
Prescription savings · · · ·
What is Cetirizine Hcl ?
If you are diagnosed with hay fever or allergies, your doctor might prescribe cetirizine. The drug is also used to treat urticaria (hives) which is an allergic skin reaction.
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Skin or whites of your eyes turn yellow.
- This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
- Talk with your doctor before taking this medicine if you are pregnant or breast feeding.
- Check with your doctor before using this medicine if you have kidney disease or liver disease.
Cetirizine Hcl Coupons & Prices
Cetirizine HCl
No Prescription Needed
Cetirizine Hcl is available over the counter — order online or pick up at a pharmacy near you.
Where to Buy Cetirizine Hcl
No prescription needed. Purchase online or in-store.
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Looking for a cetirizine HCl coupon? Cetirizine hydrochloride is the low-cost generic of Zyrtec — a once-daily, second-generation antihistamine that is much less likely to cause drowsiness than older allergy medicines. It relieves sneezing; runny nose; itchy, watery eyes; and the itching and hives of chronic idiopathic urticaria. It is sold over the counter, but a prescription version also exists, and some pharmacies price the same product differently. Enter your ZIP above to see today's price at pharmacies near you and check whether an Rx.com discount coupon beats the shelf price.
What is cetirizine HCl and how does it work?
Cetirizine hydrochloride is a second-generation antihistamine. It works as a selective peripheral H1-receptor antagonist, meaning it blocks the H1 histamine receptors that drive allergy symptoms without heavily crossing into the brain the way older antihistamines do. That is why it is much less likely to cause drowsiness than first-generation options like diphenhydramine — though it can still make some people sleepy, so it is best described as less sedating rather than truly non-drowsy.
It is used to relieve the symptoms of seasonal and perennial (year-round) allergic rhinitis — sneezing; runny nose; itchy or watery eyes; and itching of the nose or throat. It also treats chronic idiopathic urticaria (long-lasting hives of unknown cause), reducing both itching and the number of hives. It is sold over the counter under the brand name Zyrtec (including Zyrtec Allergy), plus many lower-cost store and generic versions. It comes as tablets, chewable tablets, capsules, orally disintegrating tablets, and a syrup.
How to save on cetirizine HCl with an Rx.com coupon
Even though cetirizine HCl is available over the counter, the price can vary a lot from pharmacy to pharmacy, and the generic is often cheaper than the name-brand Zyrtec box. In some cases an over-the-counter product costs less with a discount coupon — or when your doctor writes it as a prescription so it runs through the pharmacy's discount pricing. There is no manufacturer copay or savings card for this generic.
To find the best price, enter your ZIP code above to see today's cost at pharmacies near you and compare it to the Rx.com coupon price. Bring the free coupon to the pharmacy counter and ask them to run it — you do not need insurance to use it.
Cetirizine HCl vs. other allergy medicines
Cetirizine is one of several second-generation antihistamines, and the right choice often comes down to how much drowsiness you can tolerate and how fast you need relief. Cetirizine tends to work quickly and is very effective, but it is somewhat more likely to cause drowsiness than some alternatives.
- Zyrtec — the brand-name version of the same cetirizine molecule; the generic is usually less expensive.
- Levocetirizine — a closely related, refined form of cetirizine taken once daily.
- Loratadine (Claritin) and desloratadine — typically less sedating than cetirizine.
- Fexofenadine (Allegra) — generally the least sedating option, even at higher doses.
If one antihistamine does not control your symptoms or makes you too sleepy, ask your pharmacist or provider about trying another. This is general information, not medical advice.
Safety and what to know before taking it
Cetirizine HCl has no boxed warning, but it can cause drowsiness or sedation — less than first-generation antihistamines, though more than loratadine or fexofenadine. Until you know how it affects you, avoid driving or operating machinery, and avoid alcohol or other medicines that slow the nervous system. People with significant liver or kidney impairment may need a lower dose or should avoid it, and older adults should use caution.
Some people who take it daily for a long time have reported severe rebound itching (pruritus) after stopping suddenly. Rare allergic reactions, including anaphylaxis, can occur. If you are pregnant, breastfeeding, an older adult, or have kidney or liver disease, talk with your doctor or pharmacist before starting cetirizine. This information is not a substitute for professional medical advice — always follow the label and your provider's guidance.
This Cetirizine Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Cetirizine Hcl on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.