Impact-Site-Verification: 2721d812-1059-4270-b9fa-5c1654788cd1

Cilostazol Tablet — prescription drug image

Cilostazol

Cilostazol 100MG

What is Cilostazol?

Cilostazol is used to treat intermittent claudication (pain in the leg) symptoms. On average, Cilostazol is priced at about $77 for a supply of 60, 100 mg tablets. You can use our Rx.com savings offer to get a Cilostazol discount of up to 80% off of the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Cilostazol ?

Cilostazol is used to treat intermittent claudication (pain in the leg) symptoms. On average, Cilostazol is priced at about $77 for a supply of 60, 100 mg tablets. You can use our Rx.com savings offer to get a Cilostazol discount of up to 80% off of the retail price at participating pharmacies near you.
  • Unusual bleeding, bruising, or weakness
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fast, pounding, or uneven heartbeat
  • Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating
  • Fever, chills, cough, sore throat, body aches
  • Lightheadedness, dizziness, or fainting
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Unusual bleeding, bruising, or weakness
  • This medicine may cause the following problems:Heart rhythm problemsHeart problemsDecrease in number of blood cells, which may lead to bleeding or infectionsLow blood pressure
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, bleeding problems, blood clotting problems, angina, or a history of heart disease.
What is cilostazol used for?
Cilostazol is FDA-approved to reduce the symptoms of intermittent claudication — leg pain caused by peripheral arterial disease that occurs during walking or exercise — and to help people walk farther before the pain starts.
Is cilostazol a blood thinner?
Cilostazol isn't a traditional blood thinner like warfarin. It's a PDE3 inhibitor that acts as an antiplatelet and vasodilator, meaning it helps keep platelets from clumping together and helps widen blood vessels, which is different from how anticoagulants work.
Can you take cilostazol if you have heart failure?
No. Cilostazol carries a boxed warning and is contraindicated in patients with heart failure of any severity, including any NYHA class and whether ejection fraction is reduced or preserved, because this class of drug has been shown to decrease survival in patients with more advanced heart failure. Tell your provider right away if you have a history of heart failure.
How long does it take for cilostazol to work for leg pain?
The available research doesn't specify an exact timeframe in the label information reviewed here. Response can vary by person, so talk with your provider about what to expect and when to follow up if you don't notice improvement.
What foods or drugs should you avoid while taking cilostazol?
Cilostazol should be taken on an empty stomach, 30 minutes before or 2 hours after meals. It should also not be combined with certain strong CYP3A4 or CYP2C19 inhibitor medications unless your provider has specifically addressed dose adjustment, so always share your full medication list with your provider or pharmacist before starting cilostazol.
How much does Cilostazol cost without insurance?
The price of Cilostazol without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 89% off retail prices with a free Rx.com coupon.
What are the common side effects of Cilostazol?
Common side effects of Cilostazol may include: Unusual bleeding, bruising, or weakness, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Fast, pounding, or uneven heartbeat, Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating, Fever, chills, cough, sore throat, body aches. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Cilostazol?
Generic versions may be available for Cilostazol. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Cilostazol on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Cilostazol?
The cheapest pharmacy for Cilostazol depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Cilostazol near you.

Cilostazol Coupons & Prices

Cilostazol 100MG

Cilostazol Tablet — prescription drug image
Prescription
Cilostazol 100mg (14)
your area ·

Looking for a cilostazol coupon? Cilostazol is the generic form of Pletal, and because it's available from multiple manufacturers, prices can vary widely from one pharmacy to the next. Rx.com compares prices across 60,000+ pharmacies so you can see where your prescription costs less — enter your ZIP above to see today's price near you.

What is cilostazol and how does it work?

Cilostazol (brand name Pletal) is a phosphodiesterase III (PDE3) inhibitor that works as an antiplatelet and vasodilator. It's FDA-approved to reduce the symptoms of intermittent claudication — the leg pain that happens during walking or exercise in people with peripheral arterial disease — and to help improve walking distance. A generic version of cilostazol is available and can be substituted for brand-name Pletal.

Cilostazol cost and how to compare prices

Because cilostazol is generic, it's typically prescribed as the generic tablet rather than brand-name Pletal, but the price you pay can still differ a lot depending on which pharmacy fills it. There is currently no manufacturer savings card for cilostazol, so comparing pharmacy prices directly is the most reliable way to find a lower cost. Enter your ZIP code above to compare cilostazol prices at pharmacies near you across Rx.com's network of 60,000+ locations.

Cilostazol vs. other options for leg pain and clotting risk

Cilostazol isn't the only medication used for circulation or clotting-related concerns, and it works differently than several related drugs. Pentoxifylline is another medication sometimes used for claudication symptoms. Antiplatelet medications like clopidogrel and aspirin, and anticoagulants like warfarin and rivaroxaban, are used for different clotting-prevention purposes and are not direct substitutes for cilostazol — your provider chooses based on your specific condition.

Cilostazol safety information

Cilostazol carries a boxed warning: it is contraindicated in patients with heart failure of any severity, because PDE3 inhibitors as a class have been shown to decrease survival in patients with class III-IV heart failure. It should also not be combined with certain strong CYP3A4 or CYP2C19 inhibitor medications without following dose-reduction guidance from your provider. Common side effects include headache, diarrhea, abnormal stools, dizziness, and palpitations, and cilostazol can cause a faster heart rate or other heart rhythm changes; rarely, it can lower blood cell counts. Cilostazol should be taken on an empty stomach, 30 minutes before or 2 hours after meals. This is general information, not medical advice — talk with your provider or pharmacist about whether cilostazol is right for you.

Sources & accuracy

This Cilostazol information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Cilostazol on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

¿Buscando esta página en español?

Browse more medications: starting with C · full A-Z directory · by condition · common drugs

Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.