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Ciprofloxacin-Dexamethasone

Ciprofloxacin-Dexamethasone Otic (Ciprodex)

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What is Ciprofloxacin-Dexamethasone?

Ciprofloxacin-Dexamethasone Otic (Ciprodex) is a prescription ear drop used to treat outer ear infections (swimmer's ear) and certain middle ear infections in children with ear tubes. It combines an antibiotic to eliminate bacteria with a corticosteroid to reduce pain, swelling, and inflammation for faster symptom relief. 

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What is Ciprofloxacin-Dexamethasone ?

Ciprofloxacin-Dexamethasone Otic (Ciprodex) is a prescription ear drop used to treat outer ear infections (swimmer's ear) and certain middle ear infections in children with ear tubes. It combines an antibiotic to eliminate bacteria with a corticosteroid to reduce pain, swelling, and inflammation for faster symptom relief. 

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Tell your doctor if you are pregnant or breastfeeding.
  • If you have ear drainage 2 or more times within 6 months after you stop using the drops, tell your doctor.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is ciprofloxacin and dexamethasone otic used for?
It is an FDA-approved prescription ear-drop suspension used for two types of ear infection: acute otitis externa (outer-ear infection, or "swimmer's ear") in patients 6 months and older caused by susceptible Staphylococcus aureus and Pseudomonas aeruginosa, and acute otitis media (middle-ear infection) in children 6 months and older who have tympanostomy (ear) tubes, caused by susceptible bacteria. It combines the antibiotic ciprofloxacin with the steroid dexamethasone to fight infection and reduce inflammation. It is for ear use only.
Is ciprofloxacin/dexamethasone (Ciprodex) available as a generic?
Yes. Ciprofloxacin and dexamethasone otic is available as a generic version of the brand-name Ciprodex. The generic generally costs less than the brand, though cash prices still vary by pharmacy, so it helps to compare. Enter your ZIP above to see today's price near you.
How do you use ciprofloxacin and dexamethasone ear drops?
These drops are placed in the ear only, following your provider's directions and the medication guide that comes with your prescription. Keep the treated ear clean and dry, and avoid swimming or getting the ear wet unless directed. If your infection is not better after about one week, contact your provider. Do not use the drops in your eyes or by injection. Always follow the specific instructions from your doctor or pharmacist.
Can ciprofloxacin and dexamethasone otic be used in the eyes?
No. Ciprofloxacin and dexamethasone otic is for use in the ear only. It is not approved for ophthalmic (eye) use or for injection. If you have an eye concern, talk to your provider about a product intended for the eyes.
What are the side effects of ciprofloxacin and dexamethasone ear drops?
Stop the drops and contact your provider if you develop a rash or another allergic or hypersensitivity reaction; a cross-reaction is possible if you are sensitive to other quinolone antibiotics. Prolonged use may allow non-susceptible organisms, including fungi, to overgrow. If your infection has not improved after one week, your provider may need to take cultures. This is not a complete list of side effects — ask your doctor or pharmacist and read the medication guide for full information.
How much does Ciprofloxacin-dexAMETHasone 7.5ML of 0.3-0.1% cost without insurance?
The price of Ciprofloxacin-dexAMETHasone 7.5ML of 0.3-0.1% without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Ciprofloxacin-dexAMETHasone 7.5ML of 0.3-0.1%?
Common side effects of Ciprofloxacin-dexAMETHasone 7.5ML of 0.3-0.1% may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Ciprofloxacin-dexAMETHasone 7.5ML of 0.3-0.1%?
Generic versions may be available for Ciprofloxacin-dexAMETHasone 7.5ML of 0.3-0.1%. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Ciprofloxacin-dexAMETHasone 7.5ML of 0.3-0.1% on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Ciprofloxacin-dexAMETHasone 7.5ML of 0.3-0.1%?
The cheapest pharmacy for Ciprofloxacin-dexAMETHasone 7.5ML of 0.3-0.1% depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Ciprofloxacin-dexAMETHasone 7.5ML of 0.3-0.1% near you.

Ciprofloxacin-Dexamethasone Coupons & Prices

Ciprofloxacin-Dexamethasone Otic (Ciprodex)

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Ciprofloxacin-Dexamethasone Bottle — prescription drug image
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Looking for a ciprofloxacin-dexamethasone coupon? Ciprofloxacin and dexamethasone otic is the generic version of the brand-name ear-drop suspension Ciprodex, prescribed for certain ear infections. Because it is now available as a generic, it is typically much lower cost than the brand, but cash prices still vary widely from one pharmacy to another. Enter your ZIP above to see today's price at pharmacies near you, and compare across the 60,000+ pharmacies in the Rx.com network to find the lowest price on your prescription.

What is ciprofloxacin and dexamethasone otic, and how does it work?

Ciprofloxacin and dexamethasone otic is a prescription ear-drop suspension that combines two medicines: ciprofloxacin, a fluoroquinolone antibacterial that fights the bacteria causing the infection, and dexamethasone, a corticosteroid that helps reduce inflammation, swelling, and discomfort. It is sold under the brand name Ciprodex. This medication is for use in the ear only.

It is FDA-approved to treat: (1) acute otitis externa, an outer-ear infection also known as "swimmer's ear," in patients 6 months and older caused by susceptible strains of Staphylococcus aureus and Pseudomonas aeruginosa; and (2) acute otitis media, a middle-ear infection, in children 6 months and older who have tympanostomy (ear) tubes, caused by susceptible bacteria.

Cost of ciprofloxacin and dexamethasone without insurance

Ciprofloxacin and dexamethasone otic is available as a generic, which is generally far less expensive than the brand-name Ciprodex. Even so, the cash price for this ear-drop suspension can differ significantly depending on which pharmacy you use, so comparing prices before you fill it can make a real difference in what you pay out of pocket.

If you are paying without insurance, or if a coupon price beats your copay, Rx.com lets you compare live cash prices across 60,000+ U.S. pharmacies. Enter your ZIP code above to see today's price near you. If you have been prescribed the brand-name Ciprodex, the manufacturer, Alcon, also runs patient savings and assistance programs; you can review which products are currently included and the official terms, which vary and may have eligibility requirements, on Alcon's payment assistance programs page.

Related and alternative ear-infection medications

Ciprofloxacin and dexamethasone is one of several prescription ear drops used for ear infections. If you are comparing options or your provider has suggested an alternative, related medications include:

  • Ciprodex — the brand-name version of this same ciprofloxacin/dexamethasone suspension
  • Ofloxacin otic — a fluoroquinolone antibiotic ear drop
  • Neomycin, polymyxin B, and hydrocortisone otic — another combination antibiotic-plus-steroid ear drop

Which medicine is right for you depends on the type of infection and other factors. This is not medical advice; talk with your doctor or pharmacist about the best choice for your situation, and use Rx.com to compare prices once you know what you have been prescribed.

Safety and how to use it

This medication is for use in the ear only. It is not for use in the eyes (ophthalmic use) or by injection. It carries no boxed warning. Keep the infected ear or ears clean and dry, and avoid swimming or getting the ear wet unless your provider tells you otherwise. If your infection has not improved after one week of treatment, contact your provider, who may need to obtain cultures.

Stop using the drops and call your provider if a rash or other allergic or hypersensitivity reaction occurs; if you are sensitive to other quinolone antibiotics, a cross-reaction is possible. Prolonged use can allow non-susceptible organisms, including fungi, to overgrow. This medicine is not for use with a ruptured eardrum except in patients who have tympanostomy tubes for a middle-ear infection. This is general information, not medical advice — always follow your provider's directions and read the medication guide that comes with your prescription.

Sources & accuracy

This Ciprofloxacin-Dexamethasone information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Ciprofloxacin-Dexamethasone on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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