Ciprofloxacin-Dexamethasone
Ciprofloxacin-Dexamethasone Otic (Ciprodex)
What is Ciprofloxacin-Dexamethasone?
Ciprofloxacin-Dexamethasone Otic (Ciprodex) is a prescription ear drop used to treat outer ear infections (swimmer's ear) and certain middle ear infections in children with ear tubes. It combines an antibiotic to eliminate bacteria with a corticosteroid to reduce pain, swelling, and inflammation for faster symptom relief.
Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Warnings
- Tell your doctor if you are pregnant or breastfeeding.
- If you have ear drainage 2 or more times within 6 months after you stop using the drops, tell your doctor.
- Call your doctor if your symptoms do not improve or if they get worse.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Prescription savings · · · ·
What is Ciprofloxacin-Dexamethasone ?
Ciprofloxacin-Dexamethasone Otic (Ciprodex) is a prescription ear drop used to treat outer ear infections (swimmer's ear) and certain middle ear infections in children with ear tubes. It combines an antibiotic to eliminate bacteria with a corticosteroid to reduce pain, swelling, and inflammation for faster symptom relief.
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Tell your doctor if you are pregnant or breastfeeding.
- If you have ear drainage 2 or more times within 6 months after you stop using the drops, tell your doctor.
- Call your doctor if your symptoms do not improve or if they get worse.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Ciprofloxacin-Dexamethasone Coupons & Prices
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Looking for a ciprofloxacin-dexamethasone coupon? Ciprofloxacin and dexamethasone otic is the generic version of the brand-name ear-drop suspension Ciprodex, prescribed for certain ear infections. Because it is now available as a generic, it is typically much lower cost than the brand, but cash prices still vary widely from one pharmacy to another. Enter your ZIP above to see today's price at pharmacies near you, and compare across the 60,000+ pharmacies in the Rx.com network to find the lowest price on your prescription.
What is ciprofloxacin and dexamethasone otic, and how does it work?
Ciprofloxacin and dexamethasone otic is a prescription ear-drop suspension that combines two medicines: ciprofloxacin, a fluoroquinolone antibacterial that fights the bacteria causing the infection, and dexamethasone, a corticosteroid that helps reduce inflammation, swelling, and discomfort. It is sold under the brand name Ciprodex. This medication is for use in the ear only.
It is FDA-approved to treat: (1) acute otitis externa, an outer-ear infection also known as "swimmer's ear," in patients 6 months and older caused by susceptible strains of Staphylococcus aureus and Pseudomonas aeruginosa; and (2) acute otitis media, a middle-ear infection, in children 6 months and older who have tympanostomy (ear) tubes, caused by susceptible bacteria.
Cost of ciprofloxacin and dexamethasone without insurance
Ciprofloxacin and dexamethasone otic is available as a generic, which is generally far less expensive than the brand-name Ciprodex. Even so, the cash price for this ear-drop suspension can differ significantly depending on which pharmacy you use, so comparing prices before you fill it can make a real difference in what you pay out of pocket.
If you are paying without insurance, or if a coupon price beats your copay, Rx.com lets you compare live cash prices across 60,000+ U.S. pharmacies. Enter your ZIP code above to see today's price near you. If you have been prescribed the brand-name Ciprodex, the manufacturer, Alcon, also runs patient savings and assistance programs; you can review which products are currently included and the official terms, which vary and may have eligibility requirements, on Alcon's payment assistance programs page.
Related and alternative ear-infection medications
Ciprofloxacin and dexamethasone is one of several prescription ear drops used for ear infections. If you are comparing options or your provider has suggested an alternative, related medications include:
- Ciprodex — the brand-name version of this same ciprofloxacin/dexamethasone suspension
- Ofloxacin otic — a fluoroquinolone antibiotic ear drop
- Neomycin, polymyxin B, and hydrocortisone otic — another combination antibiotic-plus-steroid ear drop
Which medicine is right for you depends on the type of infection and other factors. This is not medical advice; talk with your doctor or pharmacist about the best choice for your situation, and use Rx.com to compare prices once you know what you have been prescribed.
Safety and how to use it
This medication is for use in the ear only. It is not for use in the eyes (ophthalmic use) or by injection. It carries no boxed warning. Keep the infected ear or ears clean and dry, and avoid swimming or getting the ear wet unless your provider tells you otherwise. If your infection has not improved after one week of treatment, contact your provider, who may need to obtain cultures.
Stop using the drops and call your provider if a rash or other allergic or hypersensitivity reaction occurs; if you are sensitive to other quinolone antibiotics, a cross-reaction is possible. Prolonged use can allow non-susceptible organisms, including fungi, to overgrow. This medicine is not for use with a ruptured eardrum except in patients who have tympanostomy tubes for a middle-ear infection. This is general information, not medical advice — always follow your provider's directions and read the medication guide that comes with your prescription.
This Ciprofloxacin-Dexamethasone information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Ciprofloxacin-Dexamethasone on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.