Clozapine
cloZAPine 100MG
What is Clozapine?
Clozapine is a generic drug used to treat psychotic disorders, such as schizophrenia. The average Clozapine price is about $174 for a supply of 60, 100 mg tablets. You can use our Rx.com savings offer to get an average Clozapine discount of up to 80% off of the retail price at participating pharmacies near you.Side Effects
- Sweating, muscle stiffness
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
Warnings
- Tell your doctor if you are pregnant, or if you have kidney disease, liver disease, dementia, diabetes, digestion problems, glaucoma, heart or blood vessel disease, heart failure, heart rhythm problems, high cholesterol, enlarged prostate, stomach or bowel problems, or a history of head injury, heart attack, stroke, seizures, or alcohol addiction. Tell your doctor if you smoke or drink products that contain caffeine. Tell your doctor if you have phenylketonuria.
- Do not breastfeed while you are using this medicine.
- This medicine may cause the following problems:Heart problems or changes in heart rhythmStomach or bowel problems, including severe constipationSerious skin reaction, including drug reaction with eosinophilia and systemic symptomsChanges in blood sugar levelsNeuroleptic malignant syndrome, which can be life-threateningLiver problemsIncreased risk of blood clots, including heart attack or strokeAnticholinergic effects, when used with other medicinesTardive dyskinesia (a movement disorder)
- This medicine lowers the number of white blood cells. This weakens your immune system, so you may get infections more easily. Wash your hands often. Avoid people who are sick.
- This medicine can make you dizzy, drowsy, lightheaded, or to have trouble with thinking or controlling body movements, which may lead to falls, fractures or other injuries. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you feel lightheaded or dizzy.
Prescription savings · · · ·
What is Clozapine ?
Clozapine is a generic drug used to treat psychotic disorders, such as schizophrenia. The average Clozapine price is about $174 for a supply of 60, 100 mg tablets. You can use our Rx.com savings offer to get an average Clozapine discount of up to 80% off of the retail price at participating pharmacies near you.- Sweating, muscle stiffness
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Blurred vision, confusion, trouble passing urine, eye pain, flushing or redness of the face, dry eyes, mouth, nose, or throat
- Severe constipation
- Increased thirst or hunger
- Seizures
- Lightheadedness, dizziness, fainting
- Fever, chills, cough, sore throat, body aches
- Chest pain, trouble breathing, numbness or weakness on one side of your body, lower leg pain, problems with vision, speech, or walking
- Jerky muscle movement that you cannot control, often in your face, tongue, or jaw
- Fast, slow, pounding, or uneven heartbeat
- Unusual bleeding, bruising, or weakness
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Tell your doctor if you are pregnant, or if you have kidney disease, liver disease, dementia, diabetes, digestion problems, glaucoma, heart or blood vessel disease, heart failure, heart rhythm problems, high cholesterol, enlarged prostate, stomach or bowel problems, or a history of head injury, heart attack, stroke, seizures, or alcohol addiction. Tell your doctor if you smoke or drink products that contain caffeine. Tell your doctor if you have phenylketonuria.
- Do not breastfeed while you are using this medicine.
- This medicine may cause the following problems:Heart problems or changes in heart rhythmStomach or bowel problems, including severe constipationSerious skin reaction, including drug reaction with eosinophilia and systemic symptomsChanges in blood sugar levelsNeuroleptic malignant syndrome, which can be life-threateningLiver problemsIncreased risk of blood clots, including heart attack or strokeAnticholinergic effects, when used with other medicinesTardive dyskinesia (a movement disorder)
- This medicine lowers the number of white blood cells. This weakens your immune system, so you may get infections more easily. Wash your hands often. Avoid people who are sick.
- This medicine can make you dizzy, drowsy, lightheaded, or to have trouble with thinking or controlling body movements, which may lead to falls, fractures or other injuries. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you feel lightheaded or dizzy.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Jerky muscle movement that you cannot control, often in your face, tongue, or jaw
- Lightheadedness, dizziness, fainting
- Seizures
- Unusual bleeding, bruising, or weakness
Clozapine Coupons & Prices
cloZAPine 100MG
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Clozapine prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 50mg · Tablet | 30 | $15.25 | $13.51 |
| 200mg · Tablet | 30 | $194.19 | $38.48 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
Looking for a clozapine coupon? Clozapine is the generic form of Clozaril (also sold as Versacloz and FazaClo ODT), an atypical antipsychotic used for treatment-resistant schizophrenia. Because it is available as a low-cost generic, most people pay far less than the brand price, but the exact cost still varies widely from one pharmacy to the next. Rx.com compares live cash prices across more than 60,000 U.S. pharmacies so you can find the lowest price near you. Enter your ZIP above to see today's price on clozapine.
What is clozapine and how does it work?
Clozapine is an atypical (second-generation) antipsychotic. It is FDA-approved for treatment-resistant schizophrenia, meaning severely ill patients whose symptoms have not responded adequately to standard antipsychotic medicines. It is also approved to reduce the risk of recurrent suicidal behavior in people with schizophrenia or schizoaffective disorder. Clozapine is sold under the brand names Clozaril, Versacloz, and FazaClo (an orally disintegrating tablet).
Like other antipsychotics, clozapine acts on chemical messengers in the brain, including dopamine and serotonin, to help reduce psychotic symptoms. It is not a controlled substance. This page is for general information and is not medical advice; your prescriber decides whether clozapine is right for you.
Clozapine cost and how to save without insurance
Clozapine is available as a generic, which is typically much less expensive than the brand-name versions. Even so, the cash price can differ a great deal depending on which pharmacy you use, so it truly pays to compare before you fill. There is no manufacturer savings card for generic clozapine.
Rx.com checks live prices at more than 60,000 pharmacies and shows you a free coupon you can bring to the counter, no insurance required. Prices change often and are shown live on this page, so enter your ZIP above to see today's price and find the lowest cost near you.
Clozapine vs. other antipsychotics
Clozapine is usually reserved for people who have already tried other antipsychotics without enough benefit, because of the extra monitoring it requires. Other atypical antipsychotics that prescribers may consider include olanzapine, risperidone, quetiapine, and aripiprazole. Each has a different balance of benefits and side effects.
If you have been prescribed the brand version, you can compare prices on Clozaril as well. Only your provider can decide which medicine and dose fits your situation, so talk with them before making any change.
Important safety information
Clozapine carries five FDA boxed warnings: severe neutropenia/agranulocytosis (a serious drop in infection-fighting white blood cells, in up to about 0.8% of patients); orthostatic hypotension, slow heart rate, and fainting; seizures; myocarditis and cardiomyopathy (inflammation and weakening of the heart muscle); and increased risk of death in elderly patients with dementia-related psychosis. Because of the blood-cell risk, regular absolute neutrophil count (ANC) blood tests are still clinically required.
In early 2025 the FDA eliminated the Clozapine REMS program, so prescribers, pharmacies, and patients no longer have to enroll in or report ANC results to that program. Ongoing ANC monitoring is still part of safe treatment per the drug's labeling. Tell your doctor about all your medical conditions and other medicines, and report signs of infection, fever, chest pain, fainting, or seizures right away. This information is not a substitute for advice from your own healthcare provider.
This Clozapine information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Clozapine on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.