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Creon Bottle — prescription drug image

Creon

Creon 100 Capsules Delayed Release Particles

Prescriptions & Refills
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What is Creon?

Creon is used to aid in the digestion of food. There is not a Creon generic drug currently available on the market. On average Creon is priced at about $732 for a supply of 90, 24000 units delayed-release capsules. You can use our Rx.com savings offer to get an average Creon discount of up to 80% off of the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Creon ?

Creon is used to aid in the digestion of food. There is not a Creon generic drug currently available on the market. On average Creon is priced at about $732 for a supply of 90, 24000 units delayed-release capsules. You can use our Rx.com savings offer to get an average Creon discount of up to 80% off of the retail price at participating pharmacies near you.
  • Swelling in your feet or lower legs
  • Severe stomach pain, bloating, constipation, diarrhea, nausea, or vomiting
  • Joint pain
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • This medicine is made from the pancreas of pigs. The risk of getting a virus from medicines made of pig organs has been greatly reduced in recent years. This is the result of required testing for certain viruses and testing during the making of these medicines. Although the risk is low, talk with your doctor if you have concerns.
  • Tell your doctor if you are lactose intolerant. Viokace„¢ tablets contain lactose, which can make this condition worse.
  • This medicine may cause the following problems:Fibrosing colonopathy (serious bowel disorder)High uric acid levels
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney problems, gout, high uric acid in the blood or urine (hyperuricemia or hyperuricosuria), severe pancreas disease, or bowel problems. Tell your doctor if you have trouble swallowing capsules or a history of problems with blood sugar levels.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
Is there a generic version of Creon?
No. As of 2026 there is no FDA-approved, marketed generic equivalent of Creon; it's only available as the brand-name product.
What is Creon used for?
Creon treats exocrine pancreatic insufficiency, meaning your pancreas isn't making enough digestive enzymes on its own, due to conditions such as cystic fibrosis, chronic pancreatitis, or pancreas surgery.
Does Creon have a boxed warning?
No. Creon's label includes a warning about a rare bowel condition called fibrosing colonopathy under Warnings and Precautions, but this is not an FDA boxed warning.
Does the Creon savings card work with Medicare?
No. AbbVie's savings card program for Creon excludes patients enrolled in Medicare, Medicaid, and other federal or state health programs.
How do I take Creon?
Creon is taken by mouth with meals and snacks, exactly as your doctor prescribes. Follow your prescriber's dosing instructions rather than adjusting the dose yourself.
How much does Creon cost without insurance?
The price of Creon without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Creon?
Common side effects of Creon may include: Swelling in your feet or lower legs, Severe stomach pain, bloating, constipation, diarrhea, nausea, or vomiting, Joint pain, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Creon?
Generic versions may be available for Creon. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Creon on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Creon?
The cheapest pharmacy for Creon depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Creon near you.

Creon Coupons & Prices

Creon 100 Capsules Delayed Release Particles

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Creon Bottle — prescription drug image
Prescription
Creon 100 capsules delayed release particles (30)
your area ·
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4 ED medications in one dose

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QUAD by MEDVi is a compounded prescription treatment; eligibility is determined by a licensed provider after an online visit. Pricing and product details are set by MEDVi and may change. Not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer.

Creon (pancrelipase) is a prescription pancreatic enzyme replacement used when your pancreas doesn't make enough of its own digestive enzymes. There's no marketed generic version of Creon, and pharmacy cash prices can be steep, so many patients look for a Creon coupon to help cover the cost. Enter your ZIP above to see today's price at pharmacies near you.

What Is Creon and How Does It Work?

Creon is a delayed-release capsule containing pancrelipase—a mix of lipase, protease, and amylase enzymes derived from pigs. It's FDA-approved to treat exocrine pancreatic insufficiency caused by conditions like cystic fibrosis, chronic pancreatitis, pancreatectomy, or other conditions where the pancreas can't make enough of its own digestive enzymes. Taken with meals and snacks, it helps the body digest fats, proteins, and starches.

Manufacturer Savings Card vs. Rx.com Coupon

AbbVie, the maker of Creon, offers a manufacturer savings card program, but like most brand savings cards, it's generally limited to patients with commercial (private) insurance and specific terms and eligibility rules that can change, so check AbbVie's official Creon site for current details. It explicitly does not apply to patients on Medicare, Medicaid, or other federal or state health programs. If you're uninsured, on Medicare, or your savings card is declined at the pharmacy counter, an Rx.com cash coupon can still help lower what you pay. There's no marketed generic pancrelipase product, so a manufacturer or pharmacy coupon is typically the main way to reduce the cost.

Creon vs. Other Pancreatic Enzyme Products

Creon is one of several FDA-approved pancreatic enzyme replacement products, along with brands like Zenpep, Pancreaze, and Pertzye. These products are not automatically interchangeable with one another—each has its own approved dosing and strengths—so switching between them should only be done under your doctor's direction.

Creon Safety Information

Creon carries a warning for fibrosing colonopathy, a rare bowel condition that has been reported with pancreatic enzyme products, particularly at high doses; call your doctor right away if you have unusual or severe abdominal pain, bloating, or worsening constipation. Because Creon is made from pig pancreas, it may carry a theoretical risk of transmitting viral disease, though no cases have been reported. Tell your doctor if you have gout, kidney disease, or a pork product allergy. This is general information, not medical advice—follow your prescriber's instructions and report any new or severe symptoms.

Sources & accuracy

This Creon information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Creon on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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