Dalfampridine Er
Dalfampridine ER 10MG
What is Dalfampridine Er?
Dalfampridine ER (extended-release) is a potassium channel blocker specifically formulated to improve walking in patients with multiple sclerosis (MS). This medication works by enhancing nerve signal conduction in damaged nerve fibers, which often leads to improved walking speed and mobility. Dalfampridine ER is taken orally and should be used under the guidance of a healthcare provider due to potential risks and side effects.Side Effects
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet
- Seizures
- Bloody or cloudy urine, change in how much or how often you urinate, lower back or side pain, difficult or painful urination
Warnings
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- This medicine may make you dizzy, lightheaded, or feel a constant movement of self or surroundings. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease.
- This medicine may increase the risk of seizures.
Prescription savings · · · ·
What is Dalfampridine Er ?
Dalfampridine ER (extended-release) is a potassium channel blocker specifically formulated to improve walking in patients with multiple sclerosis (MS). This medication works by enhancing nerve signal conduction in damaged nerve fibers, which often leads to improved walking speed and mobility. Dalfampridine ER is taken orally and should be used under the guidance of a healthcare provider due to potential risks and side effects.- Numbness, tingling, or burning pain in your hands, arms, legs, or feet
- Seizures
- Bloody or cloudy urine, change in how much or how often you urinate, lower back or side pain, difficult or painful urination
- Seizures
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- This medicine may make you dizzy, lightheaded, or feel a constant movement of self or surroundings. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease.
- This medicine may increase the risk of seizures.
Dalfampridine Er Coupons & Prices
Dalfampridine ER 10MG
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Dalfampridine extended-release tablets are the FDA-approved generic version of Ampyra, used to help improve walking in people with multiple sclerosis (MS). Because it's sold under its generic name by several manufacturers, cash prices for a dalfampridine er coupon can vary a lot from one pharmacy to the next — enter your ZIP above to compare prices at pharmacies near you.
What is dalfampridine ER and how does it work?
Dalfampridine is a potassium channel blocker taken as an oral extended-release tablet. It's FDA-approved to improve walking in adults with multiple sclerosis, as shown by an increase in walking speed in clinical trials. It does not treat the underlying disease process of MS and is not a disease-modifying therapy — it's used alongside a patient's regular MS treatment plan specifically to help with walking.
Comparing prices on dalfampridine ER
Since dalfampridine extended-release tablets are generic, the same 10 mg tablet can be priced very differently depending on the pharmacy, so it pays to compare. Rx.com compares prices across more than 60,000 U.S. pharmacies so you can find a lower cash price near you. The brand-name version, Ampyra, is also still available; if your plan covers Ampyra specifically or you're looking for manufacturer patient-assistance information, see the Ampyra page.
Alternatives and related MS care
Dalfampridine is the only FDA-approved medication specifically indicated to improve walking speed in MS, so there isn't a direct drug-class alternative for this particular use. It's typically used in addition to — not instead of — a disease-modifying MS therapy prescribed by a neurologist, and is often combined with physical therapy or mobility aids as part of an overall care plan.
Safety information
Dalfampridine can cause seizures, and the risk increases with higher doses or reduced kidney function. It is contraindicated in anyone with a history of seizures, moderate-to-severe kidney impairment, or a known hypersensitivity to dalfampridine or 4-aminopyridine. Your doctor should check your kidney function before you start and periodically during treatment. It can also cause serious allergic reactions in rare cases. This is general information, not medical advice — talk to your doctor or pharmacist about whether dalfampridine is right for you.
This Dalfampridine Er information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Dalfampridine Er on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.
