Domeboro
Domeboro 12 Packet
What is Domeboro?
Domeboro (aluminum sulfate and calcium acetate) is an over-the-counter medicated astringent soak used to relieve itching, irritation, and inflammation caused by poison ivy, poison oak, insect bites, eczema, athlete's foot, and other minor skin conditions. It helps dry oozing skin, soothe irritation, and promote healing of inflamed areas.
Side Effects
- New or continued redness, swelling, burning, or itching.
- Skin dryness.
Warnings
- You should not use this medicine more often or in larger amounts than your doctor ordered.
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
- Call your doctor if your symptoms do not improve or if they get worse.
Prescription savings · · · ·
What is Domeboro ?
Domeboro (aluminum sulfate and calcium acetate) is an over-the-counter medicated astringent soak used to relieve itching, irritation, and inflammation caused by poison ivy, poison oak, insect bites, eczema, athlete's foot, and other minor skin conditions. It helps dry oozing skin, soothe irritation, and promote healing of inflamed areas.
- New or continued redness, swelling, burning, or itching.
- Skin dryness.
- You should not use this medicine more often or in larger amounts than your doctor ordered.
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
- Call your doctor if your symptoms do not improve or if they get worse.
Domeboro Coupons & Prices
Domeboro 12 Packet
No Prescription Needed
Domeboro is available over the counter — order online or pick up at a pharmacy near you.
Where to Buy Domeboro
No prescription needed. Purchase online or in-store.
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Domeboro (aluminum acetate topical solution, mixed from powder packets or tablets) is an over-the-counter astringent soak used for minor skin irritation from poison ivy, insect bites, athlete's foot, and rashes caused by contact with soaps, detergents, cosmetics, or jewelry; before you buy it at the pharmacy counter, enter your ZIP above to see today's price and check whether a Rx.com domeboro coupon brings the cost down at a pharmacy near you.
What Is Domeboro and How Does It Work
Domeboro is the brand name for a powder that, once dissolved in water, forms an aluminum acetate solution (also known historically as Burow's solution). It's sold as powder packets or effervescent tablets made from aluminum sulfate tetradecahydrate and calcium acetate monohydrate, which react in water to create the astringent solution. It has no drug schedule and is regulated under the FDA's OTC skin-protectant/astringent monograph, not as a prescription drug.
Astringents like Domeboro work by gently drying and tightening irritated, weeping, or inflamed skin when applied as a cool, wet compress. The standard preparation is one packet or tablet dissolved in one pint (16 ounces) of water, applied as a wet dressing for 15 to 30 minutes, up to three times a day.
How to Save on Domeboro
Domeboro is available without a prescription, and store-brand or generic aluminum acetate soak packets are also sold as an equivalent option. Because it's OTC, insurance typically doesn't apply, but out-of-pocket prices for both the brand and generic versions vary by pharmacy and package size. Enter your ZIP code above to compare today's price at pharmacies near you and see whether a Rx.com coupon lowers the cost, whether you're buying Domeboro by name or picking up the generic aluminum acetate packets.
There is no manufacturer savings card for Domeboro since it's an OTC product.
Domeboro vs. Other Options for Skin Irritation
Domeboro isn't the only OTC choice for itchy, irritated, or rash-prone skin, and which one makes sense depends on the cause and type of irritation. Hydrocortisone cream is an anti-inflammatory steroid often used for itching and eczema-type rashes, while calamine lotion is a soothing, drying lotion commonly used for poison ivy and insect bites. Diphenhydramine (an oral or topical antihistamine) is used for itch and allergic skin reactions, and clotrimazole is an antifungal used specifically for athlete's foot rather than general irritation. Generic aluminum acetate soak packets are the direct store-brand equivalent to Domeboro.
Because Domeboro's monograph use covers a range of minor skin irritations, some people use it alongside, rather than instead of, an antifungal or antihistamine depending on what's causing the irritation.
Domeboro Safety Information
Domeboro solution is for external, topical use only — it is not meant to be taken by mouth or used in the eyes, and contact with the eyes or other mucous membranes should be avoided. Do not bandage the treated area tightly or cover it with an occlusive (airtight) dressing while using the soak.
Stop using Domeboro and check with a doctor if the skin condition gets worse, if signs of infection develop, or if irritation lasts longer than 7 days. This is general information, not medical advice — talk to your doctor or pharmacist about whether Domeboro is right for your specific skin condition.
This Domeboro information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Domeboro on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.