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Epinastine Hcl Bottle — prescription drug image

Epinastine Hcl

Epinastine HCl 5ML of 0.05%

Prescriptions & Refills
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What is Epinastine Hcl?

Elestat is used to prevent itching of the eye that is caused by allergic conjunctivitis. Epinastine Ophthalmic is the generic version. On average Elestat is priced at about $285 for 5 mL, 0.05% ophthalmic solution. You can use our Rx.com savings offer to get an average Elestat discount of up to 80% off of the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Epinastine Hcl ?

Elestat is used to prevent itching of the eye that is caused by allergic conjunctivitis. Epinastine Ophthalmic is the generic version. On average Elestat is priced at about $285 for 5 mL, 0.05% ophthalmic solution. You can use our Rx.com savings offer to get an average Elestat discount of up to 80% off of the retail price at participating pharmacies near you.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Increased itching, redness, or irritation of your eyes or eyelids
  • Burning in your eyes
  • Tell your doctor if you are pregnant or breastfeeding.
  • Do not use this medicine to treat redness or irritation that is caused by wearing contact lenses.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
Is Elestat still available?
No, the brand name Elestat has been discontinued in the US. Epinastine HCl ophthalmic solution is available today as a generic, which is what pharmacies dispense for this prescription.
What is epinastine HCl eye drops used for?
It's approved to prevent the itching that comes with allergic conjunctivitis (eye allergies).
Can I wear contact lenses when using epinastine eye drops?
Remove your contact lenses before putting in the drops, since the preservative can be absorbed by soft lenses. You can reinsert your lenses about 10 minutes after using the drops.
How often do I use epinastine eye drops?
The typical dose is one drop in each affected eye, twice a day. Follow your own prescriber's specific instructions.
How much does Epinastine Hcl cost without insurance?
The price of Epinastine Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 60% off retail prices with a free Rx.com coupon.
What are the common side effects of Epinastine Hcl?
Common side effects of Epinastine Hcl may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Increased itching, redness, or irritation of your eyes or eyelids, Burning in your eyes. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Epinastine Hcl?
Generic versions may be available for Epinastine Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Epinastine Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Epinastine Hcl?
The cheapest pharmacy for Epinastine Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Epinastine Hcl near you.

Epinastine Hcl Coupons & Prices

Epinastine HCl 5ML of 0.05%

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Epinastine Hcl Bottle — prescription drug image
Prescription
Epinastine Hcl 5ml of 0.05% (0.2)
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Epinastine HCl ophthalmic solution is an eye-drop antihistamine used to prevent itchy eyes from allergies, and people search for an "epinastine-hcl coupon" now that it's sold as a generic rather than under its old brand name, Elestat. Prices for this generic can vary by pharmacy, so it's worth comparing before you fill it. Enter your ZIP above to see today's price near you.

What is epinastine HCl and how does it work?

Epinastine HCl ophthalmic solution 0.05% is an H1 histamine receptor antagonist eye drop, FDA-approved for the prevention of itching associated with allergic conjunctivitis. It's typically used one drop in each affected eye, twice a day, during allergy flare-ups or seasonally.

The brand name Elestat is no longer marketed in the US; epinastine HCl ophthalmic solution is available today as a generic.

Comparing generic pricing

Because this drug is available only as a generic now, prices for the same prescription can still vary noticeably from pharmacy to pharmacy. Rx.com compares pricing across 60,000+ pharmacies so you can see where it costs less near you, whether you're uninsured or your plan doesn't cover eye-allergy drops well.

  • Ask your pharmacist whether an over-the-counter antihistamine eye drop might be an option for milder symptoms, since some patients don't need a prescription-strength drop
  • Compare cash prices even with insurance, since copays for eye drops can sometimes exceed the cash price

Alternatives and related allergy eye drops

Other prescription and over-the-counter antihistamine/mast-cell-stabilizer eye drops used for allergic conjunctivitis include olopatadine and ketotifen. Which one is right for you depends on symptom severity and how often you need relief; ask your eye doctor before switching products.

Safety information

No contraindications are listed for epinastine HCl ophthalmic solution. It contains a preservative (benzalkonium chloride) that can be absorbed by soft contact lenses, so contact lenses should be removed before using the drops and can be reinserted about 10 minutes later. Avoid letting the dropper tip touch your eye or any other surface to prevent contamination. This is general information, not medical advice — check with your eye doctor about your specific situation.

Sources & accuracy

This Epinastine Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Epinastine Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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