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Fycompa

Fycompa 2MG

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What is Fycompa?

Fycompa (perampanel) is a prescription medication used to treat certain types of seizures in people with epilepsy. It works by reducing abnormal electrical activity in the brain to help decrease seizure frequency and improve long-term seizure control.

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What is Fycompa ?

Fycompa (perampanel) is a prescription medication used to treat certain types of seizures in people with epilepsy. It works by reducing abnormal electrical activity in the brain to help decrease seizure frequency and improve long-term seizure control.

  • Unusual mood or behavior, thoughts of hurting yourself
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Depression, nervousness, restlessness, trouble sleeping
  • Feeling aggressive, angry, hostile, irritable
  • Swollen, painful, or tender lymph glands in the neck, armpit, or groin, yellow skin or eyes
  • Trouble walking, speaking, or controlling body movements
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or a history of depression, suicidal thoughts, or mood problems.
  • This medicine may cause the following problems: Anger, aggression, hostility, or other mood or behavior changesIncreased risk of depression or suicidal thoughtsIncreased risk for fallsDrug reaction with eosinophilia and systemic symptoms (DRESS), which can damage organs including the liver, kidney, or heart
  • This medicine may make you dizzy, drowsy, unsteady, or less alert. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Birth control pills that contain levonorgestrel may not work as well while you use this medicine. Use another form of birth control together with your pills during treatment with this medicine and for at least 1 month after the last dose. Talk to your doctor if you have questions.
What is Fycompa (perampanel) used to treat?
Fycompa is FDA-approved for partial-onset (focal) seizures, with or without secondarily generalized seizures, in patients 4 years and older. For this focal-seizure indication it can be used either on its own (monotherapy) or as an add-on (adjunctive) therapy with other seizure medicines. It is also approved as add-on (adjunctive) therapy for primary generalized tonic-clonic (PGTC) seizures in patients 12 years and older who have idiopathic generalized epilepsy.
Is Fycompa a controlled substance?
Yes. Fycompa (perampanel) is a Schedule III (C-III) controlled substance, meaning it has a recognized potential for abuse and for physical or psychological dependence. Because of this, it should be taken exactly as prescribed and should not be stopped abruptly, since stopping suddenly can increase seizure frequency.
Is there a generic version of Fycompa available?
Yes. A generic version, perampanel, is available. The generic is usually much less expensive than brand-name Fycompa, so it is often the biggest way to save. Ask your prescriber or pharmacist whether generic perampanel is appropriate for you, then enter your ZIP above to compare cash prices.
What are the most serious side effects of Fycompa?
Fycompa has a boxed warning for serious or life-threatening psychiatric and behavioral reactions, including aggression, hostility, irritability, anger, and homicidal ideation or threats, which are more likely at higher doses. Like other antiseizure drugs, it also carries a risk of suicidal thoughts or behavior. It can rarely cause a serious rash, including DRESS. Watch for mood or behavior changes and contact your provider right away if they occur. Do not drink alcohol while taking it.
How much does Fycompa cost with a savings card?
Prices change and depend on your pharmacy, dose, and coverage, so we show today's cash price live on this page when you enter your ZIP above. The manufacturer's savings card is generally limited to people with commercial (private) insurance and typically excludes Medicare and Medicaid; check current terms at the official Fycompa savings card page. If you are uninsured, on Medicare, or the card is declined, a free Rx.com cash coupon may be your best option, and asking about generic perampanel is usually the largest saving.
How much does Fycompa 2MG cost without insurance?
The price of Fycompa 2MG without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Fycompa 2MG?
Common side effects of Fycompa 2MG may include: Unusual mood or behavior, thoughts of hurting yourself, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Depression, nervousness, restlessness, trouble sleeping, Feeling aggressive, angry, hostile, irritable, Swollen, painful, or tender lymph glands in the neck, armpit, or groin, yellow skin or eyes. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Fycompa 2MG?
Generic versions may be available for Fycompa 2MG. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Fycompa 2MG on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Fycompa 2MG?
The cheapest pharmacy for Fycompa 2MG depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Fycompa 2MG near you.

Fycompa Coupons & Prices

Fycompa 2MG

Prescriptions & Refills
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Prescription
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Looking for a Fycompa coupon? Fycompa (perampanel) is a brand-name antiseizure medicine used to treat certain focal (partial-onset) seizures and, as add-on therapy, primary generalized tonic-clonic seizures. Whether you have insurance, Medicare, or no coverage at all, you can compare pharmacy prices and use a free Rx.com cash coupon at the pharmacy counter. Enter your ZIP above to see today's price near you, and read on to learn how the Rx.com cash coupon compares with the manufacturer's savings card and the lower-cost generic, perampanel.

What is Fycompa and how does it work?

Fycompa is the brand name for perampanel, an antiseizure (antiepileptic) drug. It belongs to a class known as non-competitive AMPA glutamate receptor antagonists. In plain terms, it works in the brain to calm the overactive nerve signaling that can lead to seizures. It comes as oral tablets and as an oral liquid suspension.

For partial-onset (focal) seizures, with or without secondarily generalized seizures, Fycompa is FDA-approved for use either on its own (monotherapy) or as an add-on (adjunctive) therapy alongside other seizure medicines, in patients 4 years and older. For primary generalized tonic-clonic (PGTC) seizures in patients 12 years and older with idiopathic generalized epilepsy, it is approved only as add-on therapy. Your prescriber decides whether it fits your specific type of epilepsy and whether to use it alone or in combination.

Fycompa cost: manufacturer savings card vs. Rx.com cash coupon

There are a few ways to lower what you pay for Fycompa, and the best one depends on your insurance situation. Enter your ZIP above to see today's Rx.com cash price at pharmacies near you.

  • Manufacturer savings card: The maker of Fycompa offers a savings card program. These commercial copay cards are generally limited to people with commercial (private) insurance and typically exclude Medicare, Medicaid, and other government coverage. Terms, eligibility, and any limits vary and can change, so check the official details at the Fycompa savings card program page.
  • Rx.com cash coupon: Our free coupon is a cash-price discount, not insurance. It is a good option if you are uninsured, if you have Medicare or another plan the manufacturer card excludes, or if the manufacturer card is declined at the counter. You cannot combine a cash coupon with your insurance on the same fill, so compare both and use whichever is lower.
  • Ask about patient assistance: If cost is a barrier, ask your prescriber or pharmacist whether a manufacturer patient-assistance program or other help is available for your situation.

The biggest savings lever is the generic. A generic version, perampanel, is available and is usually far less expensive than brand-name Fycompa. Ask your prescriber or pharmacist whether generic perampanel is right for you, then enter your ZIP above to compare cash prices.

Fycompa alternatives and related seizure medicines

Fycompa can be used on its own or alongside other epilepsy medicines for focal seizures, and only your prescriber can decide which drug or combination fits your seizure type and history. These related medications are commonly discussed:

  • Perampanel — the generic form of Fycompa itself, and usually the lowest-cost way to get the same medicine.
  • Keppra (levetiracetam)
  • Lamictal (lamotrigine)
  • Vimpat (lacosamide)
  • Briviact (brivaracetam)

You can look up the cash price for any of these on Rx.com. Never switch or stop a seizure medicine on your own; talk with your provider first.

Fycompa safety and side effects

Fycompa carries a boxed warning, the FDA's strongest warning. Serious or life-threatening psychiatric and behavioral reactions, including aggression, hostility, irritability, anger, and homicidal ideation or threats, have occurred, more often at higher doses. Anyone taking Fycompa should be monitored for changes in mood or behavior, especially while the dose is being increased and at higher doses; the dose may need to be reduced or the drug stopped if these occur. Like other antiseizure drugs, Fycompa also carries a class-wide risk of suicidal thoughts or behavior.

More common side effects include dizziness, sleepiness, fatigue, irritability, falls, and problems with walking or balance, as well as weight gain. Fycompa can rarely cause a serious rash, including a reaction called DRESS. It is a Schedule III controlled substance, meaning it has a potential for abuse and dependence, so use it exactly as prescribed and do not stop it abruptly, since suddenly stopping can increase seizures. Do not drink alcohol while taking Fycompa, as this can worsen anger and aggression and increase drowsiness. This information is a summary and is not medical advice; talk with your doctor or pharmacist about your full medical history and any concerns.

Sources & accuracy

This Fycompa information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Fycompa on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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