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Humulin

Humulin 10ML of 100UNIT/ML

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What is Humulin?

Humulin is a type of human insulin used to help control blood sugar levels in people with type 1 or type 2 diabetes. It replaces the insulin that the body normally produces, helping to manage blood sugar effectively.

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What is Humulin ?

Humulin is a type of human insulin used to help control blood sugar levels in people with type 1 or type 2 diabetes. It replaces the insulin that the body normally produces, helping to manage blood sugar effectively.

Source: MedlinePlus, U.S. National Library of Medicine

  • Dry mouth, increased thirst, muscle cramps, nausea or vomiting, uneven heartbeat
  • Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing, tiredness
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or heart disease (including heart failure).
  • This medicine may cause the following problems:Low blood sugar or low potassium levels in the bloodFluid retention or heart failure (when used together with a thiazolidinedione [TZD] medicine)
  • This medicine can cause low blood sugar. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Never share insulin pens or needles with anyone. Sharing these can pass hepatitis viruses, HIV, and other illnesses from one person to another.
What is the difference between Humulin R and Humulin N?
Humulin R is regular, short-acting insulin that starts working relatively quickly and covers blood sugar over a shorter window, often around meals. Humulin N is NPH, an intermediate-acting insulin that works more slowly and lasts longer to provide background coverage. Many people use them at different times, and Humulin 70/30 combines both in one premixed pen or vial. Your provider decides which form fits your routine.
Is Humulin the same as Novolin?
No, they are different brands, but they are very similar. Humulin is made by Eli Lilly and Novolin by Novo Nordisk, and both are human insulins offered in matching forms (regular, NPH, and 70/30 premix). Even though they are comparable, you should not switch between them without your provider's guidance, since the change can affect your blood sugar control.
Can you buy Humulin over the counter without a prescription?
In most U.S. states, the vial forms of Humulin R and Humulin N can be purchased over the counter without a prescription. However, the KwikPen and the concentrated Humulin R U-500 forms are prescription-only. Even where it is available over the counter, insulin should only be used under the direction of a healthcare provider because dosing errors and low blood sugar can be dangerous.
How much does Humulin cost with the Lilly savings card?
Eli Lilly offers an insulin savings program through its official insulins savings and support site, but the exact out-of-pocket amount, eligibility, and terms vary and can change, and manufacturer co-pay cards are generally limited to people with commercial insurance. We do not quote specific dollar figures because prices change and depend on your pharmacy and coverage. If you are uninsured, on Medicare, or the card does not apply, enter your ZIP above to see today's Rx.com cash coupon price at pharmacies near you.
How long does Humulin 70/30 take to start working?
Humulin 70/30 is a premix of 70% NPH (intermediate-acting) and 30% regular (short-acting) insulin, so the regular portion begins lowering blood sugar within about half an hour while the NPH portion provides longer, background coverage. Because timing varies from person to person, follow your provider's directions on exactly when to inject it relative to meals.
How much does Humulin cost without insurance?
The price of Humulin without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Humulin?
Common side effects of Humulin may include: Dry mouth, increased thirst, muscle cramps, nausea or vomiting, uneven heartbeat, Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing, tiredness, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Humulin?
Generic versions may be available for Humulin. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Humulin on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Humulin?
The cheapest pharmacy for Humulin depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Humulin near you.

Humulin Coupons & Prices

Humulin 10ML of 100UNIT/ML

Prescriptions & Refills
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Humulin Vial — prescription drug image
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Humulin prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
3ml of 100unit/ml · Vial 3 $17.88
10ml of (70-30) 100unit/ml · Vial 10 $211.99 $50.12
10ml of 100unit/ml · Vial 10 $66.91 $50.12

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for a Humulin coupon? Rx.com offers a free cash-price coupon on Humulin (insulin human, made by Eli Lilly) that you can use at pharmacies near you whether you have insurance or not. Humulin comes in several forms including Humulin R (regular), Humulin N (NPH), and Humulin 70/30 (premix), all used to control high blood sugar in diabetes. Enter your ZIP above to see today's price at pharmacies close to you, then show the coupon at the counter to pay the cash price.

What is Humulin and how does it work?

Humulin is a brand of human insulin from Eli Lilly used to treat diabetes mellitus (type 1 and type 2) by lowering high blood sugar. Insulin is the hormone your body uses to move sugar from the blood into cells for energy; people with diabetes either do not make enough of it or cannot use it well. Humulin is offered in several forms so treatment can be matched to your needs:

  • Humulin R — regular, short-acting insulin
  • Humulin N — NPH, intermediate-acting insulin
  • Humulin 70/30 — a premix of 70% NPH and 30% regular insulin
  • Humulin R U-500 — a concentrated (5x) regular insulin for people with severe insulin resistance who need more than 200 units a day

Humulin may be used on its own or combined with other insulins or oral diabetes medicines. Your provider decides which form and dose are right for you, so use this page for general information, not as medical advice.

Humulin cost: manufacturer savings card vs. Rx.com cash coupon

Eli Lilly runs an official insulin savings program (the Lilly Insulin Value Program and its co-pay savings card, described on Lilly's insulins savings and support site). Manufacturer co-pay cards like this are generally limited to people with commercial or private insurance, and the exact terms, eligibility, and any caps vary and change over time, so read the current program details before you rely on it. These cards typically cannot be used if you are uninsured or have government coverage such as Medicare or Medicaid.

That is where the Rx.com cash coupon fills the gap. Our coupon is a discount on the cash price, so it works whether you are uninsured, on Medicare, or in a situation where a manufacturer card is declined or does not apply. There is currently no generic version of Humulin, so comparing pharmacy cash prices is the main way to save. Enter your ZIP above to see today's Humulin price at pharmacies near you. Lilly also offers patient-assistance support for people who qualify by income, which is worth asking about if cost is a barrier.

Humulin alternatives and related insulins

Humulin's closest counterpart is Novolin from Novo Nordisk, which offers matching human-insulin forms (regular, NPH, and 70/30). Because these are human insulins, they tend to cost less than the newer analog insulins, which act faster or last longer. Common analog options your provider might discuss include:

Never switch insulin products, strengths, manufacturers, or types on your own — even between similar-sounding forms — because the change can cause dangerous high or low blood sugar. Any switch should be made with close guidance from your provider. You can compare cash coupon prices for any of these on Rx.com by entering your ZIP.

Important safety information

Humulin has no boxed warning, but the most important risk is hypoglycemia (low blood sugar), which can be severe and even life-threatening. The risk goes up with dose changes, missed meals, extra exercise, and certain drug interactions, so learn the warning signs and how to treat a low. Insulin can also lower potassium, which in serious cases can cause muscle weakness or heart rhythm problems. Never share pens or needles with anyone, even with a new needle, because of infection risk.

Humulin R U-500 is five times more concentrated than standard insulin, so dosing errors are especially dangerous — always use the dedicated U-500 syringe or pen. Serious allergic reactions and injection-site reactions (including lumps or skin changes from reusing the same spot) can occur, and extra caution is needed if you take thiazolidinedione medicines because of fluid retention. This is general information and not medical advice; talk with your doctor or pharmacist about your specific situation before making any changes.

Sources & accuracy

This Humulin information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Humulin on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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