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Levonorgestrel-Ethinyl Estrad Disp Pack — prescription drug image

Levonorgestrel-Ethinyl Estrad

Levonorgestrel-Ethinyl Estrad 28 Tablets

Women's Health Care
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What is Levonorgestrel-Ethinyl Estrad?

Amethyst is a contraceptive drug used to prevent pregnancy. Ethinyl Estradiol/Norethindrone is the generic version of the brand-name Amethyst. Amethyst costs around $24 for a supply of 28, 90 mcg/20 mcg tablets. You can use our Rx.com Amethyst savings card to save on the cost of your prescription when you purchase from any of the pharmacies participating locally.

Prescription savings · · · ·

What is Levonorgestrel-Ethinyl Estrad ?

Amethyst is a contraceptive drug used to prevent pregnancy. Ethinyl Estradiol/Norethindrone is the generic version of the brand-name Amethyst. Amethyst costs around $24 for a supply of 28, 90 mcg/20 mcg tablets. You can use our Rx.com Amethyst savings card to save on the cost of your prescription when you purchase from any of the pharmacies participating locally.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Breast lumps, pain, swelling, tenderness, or discharge
  • Change in how much or how often you urinate
  • Yellowing of your skin or the whites of your eyes.
  • Chest pain or tightness, trouble breathing, coughing up blood
  • Dark urine, pale stools, loss of appetite, yellow skin or eyes
  • Heavy vaginal bleeding
  • Irregular, late, or missed menstrual periods
  • Numbness or weakness in your arm or leg, or on one side of your body
  • Pain in your lower leg (calf)
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Vision loss, double or blurred vision
  • Sudden and severe stomach pain, nausea, vomiting, lightheadedness
  • Sudden or severe headache, problems with vision, speech, or walking
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • This medicine will not protect you from getting HIV/AIDS or other sexually transmitted diseases.
  • You might have some light bleeding or spotting when you first start using this medicine. This is usually normal and should not last long. However, if you have heavy bleeding or the bleeding lasts more than seven days in a row, call your doctor€™s office.
  • If you miss two periods in a row, call your doctor for a pregnancy test before you take any more pills.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Sweating, nausea or vomiting, pain in your chest, jaw, and left arm.
  • Swelling in your hands, ankles, or feet.
  • Unusual bleeding or bruising.
  • Yellowing of your skin or the whites of your eyes.
  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you are breastfeeding, or if you have recently been pregnant. Tell your doctor if you have high blood pressure, high cholesterol, diabetes, breast lumps, migraine headache, hereditary angioedema, or a history of depression, epilepsy, gallbladder disease, heart disease, kidney disease, or irregular monthly periods. Tell your doctor if you smoke, wear contact lenses, or if you are having surgery that requires inactivity for a long time.
  • This medicine may cause the following problems:Increased risk of heart attack, stroke, or blood clotsIncreased risk of cancer (including cancer of the breast, endometrium, ovaries, and cervix)Liver problems (including liver tumor or cancer)Eye or vision problemsGallbladder diseaseHigh cholesterol in the bloodHigh blood pressure
What is levonorgestrel and ethinyl estradiol used for?
It's a combination hormonal birth control pill FDA-approved to prevent pregnancy. It works mainly by stopping ovulation, along with changes to cervical mucus and the uterine lining. It does not protect against HIV or other sexually transmitted infections.
How effective are levonorgestrel/ethinyl estradiol pills at preventing pregnancy?
As a combination oral contraceptive, it works primarily by inhibiting ovulation. How well any birth control pill works depends heavily on taking it consistently and correctly as prescribed. Talk with your provider about how to take it and what to do if you miss a dose.
What are the common and serious side effects of levonorgestrel and ethinyl estradiol?
The most important safety information concerns serious cardiovascular risks: this medication carries a boxed warning that cigarette smoking increases the risk of serious cardiovascular events such as blood clots, stroke, and heart attack, especially in women over 35 who smoke. Other serious risks include venous thromboembolism, stroke, and heart attack, particularly in women with additional risk factors. Review the full medication guide with your pharmacist or provider for a complete list of common and serious side effects.
Who should not take levonorgestrel and ethinyl estradiol (who is at risk of blood clots)?
Women who smoke, especially those over 35, should not use combination hormonal contraceptives like this one. It's also not appropriate for women with a history of blood clots or clotting disorders, coronary artery or cerebrovascular disease, certain heart valve conditions, known or suspected breast cancer or other estrogen-sensitive cancer, undiagnosed abnormal uterine bleeding, liver disease or liver tumors, or pregnancy. Risk is also higher with other factors such as high blood pressure, diabetes, obesity, or migraine with aura. Discuss your full health history with your provider before starting.
Can levonorgestrel and ethinyl estradiol be used as emergency contraception?
No combination ethinyl estradiol and levonorgestrel product is currently FDA-approved or marketed in the U.S. specifically for emergency contraception — the one that once was (Preven) was discontinued in 2004. Taking extra doses of a regular combination pill like this one for emergency contraception (sometimes called the Yuzpe method) is an off-label use, though published studies suggest it can reduce pregnancy risk by roughly 74% when started within 72 hours of unprotected intercourse. Dedicated, FDA-approved emergency contraception options — such as levonorgestrel-only Plan B (available over the counter) or ulipristal acetate/ella (by prescription) — are generally more effective and are the recommended first choice. Don't take extra doses of this medication on your own for emergency contraception; talk to your pharmacist or provider first.
How much does Levonorgestrel-Ethinyl Estrad cost without insurance?
The price of Levonorgestrel-Ethinyl Estrad without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 37% off retail prices with a free Rx.com coupon.
What are the common side effects of Levonorgestrel-Ethinyl Estrad?
Common side effects of Levonorgestrel-Ethinyl Estrad may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Breast lumps, pain, swelling, tenderness, or discharge, Change in how much or how often you urinate, Yellowing of your skin or the whites of your eyes., Chest pain or tightness, trouble breathing, coughing up blood. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Levonorgestrel-Ethinyl Estrad?
Generic versions may be available for Levonorgestrel-Ethinyl Estrad. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Levonorgestrel-Ethinyl Estrad on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Levonorgestrel-Ethinyl Estrad?
The cheapest pharmacy for Levonorgestrel-Ethinyl Estrad depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Levonorgestrel-Ethinyl Estrad near you.

Levonorgestrel-Ethinyl Estrad Coupons & Prices

Levonorgestrel-Ethinyl Estrad 28 Tablets

Women's Health Care
Licensed US providers · Online visit in minutes
Levonorgestrel-Ethinyl Estrad Disp Pack — prescription drug image
Prescription
Levonorgestrel-Ethinyl Estrad 1 package (28 tablets), 0.1-20mg-mcg (1)
your area ·
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

If you're comparing prices for a levonorgestrel and ethinyl estradiol coupon, you're looking at one of the most widely prescribed combination birth control pills in the U.S. — a well-established generic combination oral contraceptive that isn't tied to a single originator brand. Because it's sold under a wide range of generic-equivalent brand names, the price for the exact same medication can still vary quite a bit from one pharmacy to the next. Rx.com compares pricing across more than 60,000 U.S. pharmacies so you can see where your prescription costs less — enter your ZIP above to see today's price.

What Is Levonorgestrel and Ethinyl Estradiol?

Levonorgestrel and ethinyl estradiol is a combination hormonal oral contraceptive that pairs a progestin (levonorgestrel) with an estrogen (ethinyl estradiol). It's FDA-approved for the prevention of pregnancy in women who choose oral contraceptives as their birth control method. It works primarily by inhibiting ovulation, with secondary effects on cervical mucus and the uterine lining. Like all hormonal contraceptives, it does not protect against HIV or other sexually transmitted infections.

This exact combination is sold under many generic-equivalent brand names — including Aviane, Altavera, Chateal, Falmina, Kurvelo, Larissia, Lessina, Levora, Lutera, Marlissa, Orsythia, Sronyx, Vienva, and Portia — because it's a well-established generic formulation rather than a drug tied to one flagship originator brand. (Nordette, an earlier brand in this same class, has been discontinued in the U.S.; Levora is commonly cited as its generic successor.)

Levonorgestrel/Ethinyl Estradiol Coupon: Comparing Prices

Because levonorgestrel and ethinyl estradiol is already available generically and is dispensed under dozens of interchangeable brand and generic labels, the price you're quoted can differ depending on which pharmacy fills it and which label they carry. There isn't a manufacturer savings card tied to this combination, since it isn't marketed under one flagship brand — so comparing pharmacy cash prices is the most reliable way to find a lower cost near you.

Rx.com checks pricing across more than 60,000 pharmacies nationwide, including major chains and independents, so you can compare before you fill. Enter your ZIP code above to see today's price at pharmacies near you.

Alternatives and Related Contraceptives

If your provider is weighing other hormonal contraceptive options, several related medications work in similar ways. Drospirenone and ethinyl estradiol and norgestimate and ethinyl estradiol are other combination pills that pair ethinyl estradiol with a different progestin. Norethindrone is a progestin-only ("mini pill") option for women advised to avoid estrogen. Levonorgestrel alone is used in emergency contraception and in progestin-only IUDs, and medroxyprogesterone is a progestin-only injectable contraceptive option.

Only your prescriber can determine which contraceptive option is appropriate for you based on your health history and risk factors.

Safety Information

Combination oral contraceptives like this one carry a boxed warning: cigarette smoking increases the risk of serious cardiovascular side effects, including blood clots, stroke, and heart attack. This risk increases with age, particularly in women over 35, and with the number of cigarettes smoked. Women who smoke should not use combination hormonal contraceptives, particularly if they are over 35.

Additional risks include venous thromboembolism (blood clots in the legs or lungs), stroke, and heart attack, especially with other risk factors such as high blood pressure, diabetes, obesity, migraine with aura, or a personal or family history of blood clots. This medication is not appropriate for women with a history of blood clots or clotting disorders, coronary artery or cerebrovascular disease, certain heart valve conditions, known or suspected breast cancer or other estrogen-sensitive cancer, undiagnosed abnormal uterine bleeding, liver disease or liver tumors, or pregnancy. Seek emergency care right away for sudden chest pain, shortness of breath, leg pain or swelling, a severe headache, vision changes, or weakness or numbness — these can be signs of a blood clot, stroke, or heart attack. This is general information, not medical advice; talk with your prescriber about whether this medication is right for you.

Sources & accuracy

This Levonorgestrel-Ethinyl Estrad information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Levonorgestrel-Ethinyl Estrad on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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