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Lithium Carbonate

Lithium Carbonate 300MG

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What is Lithium Carbonate?

Lithium carbonate is a medication primarily used to treat and prevent episodes of mania in people with bipolar disorder. It helps to stabilize mood and reduce the frequency and severity of mood swings. Lithium carbonate is often part of long-term management and requires regular monitoring due to its narrow therapeutic range and potential side effects.

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What is Lithium Carbonate ?

Lithium carbonate is a medication primarily used to treat and prevent episodes of mania in people with bipolar disorder. It helps to stabilize mood and reduce the frequency and severity of mood swings. Lithium carbonate is often part of long-term management and requires regular monitoring due to its narrow therapeutic range and potential side effects.
  • Unusual tiredness or weakness
  • Fast, pounding, or uneven heartbeat
  • Diarrhea, vomiting, tremors, or drowsiness
  • Fever
  • Confusion, problems with walking or balance, muscle movements you cannot control
  • Lightheadedness or fainting
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate
  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you have kidney problems, heart or blood vessel disease (including Brugada syndrome), brain or nerve problems, or thyroid problems.
  • This medicine may cause the following problems:Lithium toxicityHeart problemsKidney problemsBrain problems (including encephalopathic syndrome, pseudotumor cerebri)Serotonin syndrome (when used with certain medicines)
  • Make sure any doctor or dentist who treats you knows that you are using this medicine.
  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Maintain adequate fluid intake, salt intake, and a normal diet, especially during the stabilization period.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is lithium carbonate used for?
Lithium carbonate is FDA-approved as a single-drug treatment for bipolar I disorder. It treats acute manic and mixed episodes in people 7 years and older, and it is also approved for maintenance treatment in people 7 years and older to help prevent episodes from returning. It is a mood stabilizer, not an antipsychotic or an anticonvulsant.
Why do you need regular blood tests while taking lithium?
The dose of lithium that helps is close to the dose that can cause toxicity, so your prescriber measures the actual lithium level in your blood rather than guessing from the dose. The FDA label's boxed warning says facilities for prompt and accurate serum lithium testing should be available before therapy is started. Along with lithium levels, your prescriber will periodically check kidney function, thyroid function and calcium, because long-term lithium can affect all three.
What are the warning signs of lithium toxicity?
Early signs include diarrhea, vomiting, drowsiness, muscle weakness and lack of coordination. Higher levels can cause unsteady walking, dizziness, blurred vision, ringing in the ears, frequent urination, confusion and seizures, and severe toxicity can be fatal. Contact your prescriber or seek medical care right away if any of these show up, especially if you have been dehydrated, ill with vomiting or diarrhea, or started a new medicine.
What medications and foods should you avoid while taking lithium?
Several common medicines raise lithium levels and can trigger toxicity: NSAIDs, thiazide and loop diuretics, ACE inhibitors and ARBs, and metronidazole. Serotonergic drugs can raise the risk of serotonin syndrome. On the food and drink side, avoid large swings in your salt or fluid intake and try not to get dehydrated, since low sodium and dehydration both push lithium levels up. A separate group of medicines works the other way: alkalinizing agents such as sodium bicarbonate increase how much lithium your kidneys get rid of and can lower your level, so the concern there is the medicine not working, not toxicity. Either direction matters, so check with your pharmacist before adding any new prescription or over-the-counter product.
Is there a generic for lithium carbonate, and how do I get the best price?
Lithium carbonate is itself the generic; the extended-release brand is Lithobid. Prices for the generic still vary from pharmacy to pharmacy, so it pays to compare rather than assume your usual store is cheapest. Enter your ZIP above to see today's cash price at pharmacies near you and show the Rx.com coupon at the counter. The coupon is for cash-paying customers and cannot be combined with insurance.
How much does Lithium Carbonate cost without insurance?
The price of Lithium Carbonate without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 70% off retail prices with a free Rx.com coupon.
What are the common side effects of Lithium Carbonate?
Common side effects of Lithium Carbonate may include: Unusual tiredness or weakness, Fast, pounding, or uneven heartbeat, Diarrhea, vomiting, tremors, or drowsiness, Fever, Confusion, problems with walking or balance, muscle movements you cannot control. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Lithium Carbonate?
Generic versions may be available for Lithium Carbonate. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Lithium Carbonate on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Lithium Carbonate?
The cheapest pharmacy for Lithium Carbonate depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Lithium Carbonate near you.

Lithium Carbonate Coupons & Prices

Lithium Carbonate 300MG

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Lithium Carbonate Capsule — prescription drug image
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A lithium carbonate coupon from Rx.com lets you compare cash prices for this mood stabilizer at more than 60,000 pharmacies before you fill your prescription. Lithium carbonate is a generic medicine, but what you actually pay without insurance can differ a lot from one pharmacy to the next, even between stores in the same town. Enter your ZIP code above to see today's price near you, then show the coupon at the counter.

What is lithium carbonate and how does it work?

Lithium carbonate is an antimanic agent, or mood stabilizer. It is a salt of the alkali metal lithium, and it is not an antipsychotic and not an anticonvulsant, even though it is often used alongside or compared with medicines from those classes. It is FDA-approved as a single-drug (monotherapy) treatment for bipolar I disorder: for acute manic and mixed episodes in people 7 years and older, and for maintenance treatment in people 7 years and older.

Lithium carbonate is sold as a generic and under the brand name Lithobid, an extended-release tablet. Several older brands (Eskalith, Eskalith CR, Lithonate and Lithotabs) are no longer marketed in the US. Because the amount of lithium in your blood matters so much, any change between immediate-release and extended-release forms is a decision for your prescriber, who will tell you what monitoring you need.

Lithium carbonate cost and coupon savings

Lithium carbonate is available as a generic, which is usually the least expensive way to fill it, but generic pricing is not the same everywhere. Cash prices for the same strength and quantity can vary widely between a chain drugstore, a grocery pharmacy and an independent, which is exactly why comparing is worth the two minutes.

Rx.com compares cash prices at more than 60,000 pharmacies. Enter your ZIP above to see today's price for your strength and quantity, print or show the coupon, and hand it to the pharmacist. The coupon is for cash-paying customers and cannot be combined with insurance, so if you do have coverage it is worth asking the pharmacy to run both and charge you the lower one. If you were prescribed a brand version, check the manufacturer's website for any current savings program before you fill. Keep in mind lithium therapy also involves periodic lab work, which is billed separately from the prescription.

Lithium carbonate vs. other mood stabilizers

Lithium is one of several options for bipolar I disorder, and the right one depends on your history, your other health conditions and what you can tolerate. Only your prescriber can make that call. Other medicines commonly used in bipolar disorder include:

If you were prescribed the extended-release brand, you can compare prices on our Lithobid page. Do not stop or switch a mood stabilizer on your own, even to save money. Ask your prescriber or pharmacist first, then use Rx.com to price whatever they decide on.

Lithium carbonate safety and monitoring

Lithium carbonate carries an FDA boxed warning: lithium toxicity is closely related to the level of lithium in your blood, and it can happen at doses close to the ones that treat you. The label says facilities for prompt and accurate serum lithium testing should be available before therapy is started. Early signs of toxicity include diarrhea, vomiting, drowsiness, muscle weakness and poor coordination. At higher levels people can have unsteady walking, dizziness, blurred vision, ringing in the ears, frequent urination, confusion, seizures, and toxicity can be fatal. Call your prescriber right away if these appear.

Dehydration, low sodium and certain drugs can push lithium levels up, including NSAIDs, thiazide and loop diuretics, ACE inhibitors and ARBs (renin-angiotensin system antagonists), and metronidazole. Avoid big swings in your salt or fluid intake. Separately, and in the opposite direction, alkalinizing agents such as sodium bicarbonate increase how much lithium your kidneys excrete and can lower your lithium level, which risks the medicine not working rather than causing toxicity; do not start one without telling your prescriber, who may need to check your level more often.

Labeled risks include lithium-induced polyuria and nephrogenic diabetes insipidus, chronic kidney disease, hyponatremia (low blood sodium, which can range from no symptoms to stupor, seizures or coma at severe levels), an encephalopathic syndrome reported in people treated with lithium together with an antipsychotic, serotonin syndrome with serotonergic drugs, hypothyroidism or hyperthyroidism, hypercalcemia and hyperparathyroidism, unmasking of Brugada syndrome, and pseudotumor cerebri.

On pregnancy, the label notes that early reports suggested an increase in cardiovascular malformations, particularly Ebstein's anomaly, with first-trimester use, but that subsequent studies indicate the increased risk for cardiac malformations is likely to be small, and the data are insufficient to establish a drug-associated risk. Breastfeeding is not recommended with maternal lithium use; if someone does choose to breastfeed, the infant should be closely monitored for signs of lithium toxicity. Tell your prescriber if you are pregnant, may become pregnant or are breastfeeding, so you can weigh the options together. Expect periodic blood tests for lithium level, kidney function, thyroid function and calcium. This is general information, not medical advice; talk with your provider or pharmacist about your situation.

Sources & accuracy

This Lithium Carbonate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Lithium Carbonate on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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