Orphenadrine-Aspirin-Caffeine Coupons & Prices

Looking for an orphenadrine-aspirin-caffeine coupon? This combination tablet (orphenadrine citrate, aspirin, and caffeine, sold generically and historically known under brand names like Norgesic) is available as a generic, but the price you're quoted can still vary a lot from one pharmacy to the next. Rx.com compares prices at more than 60,000 U.S. pharmacies, so before you fill this prescription, enter your ZIP above to see today's price near you and make sure you're not overpaying for the exact same medication.

What is orphenadrine, aspirin, and caffeine?

Orphenadrine, aspirin, and caffeine is a combination prescription tablet that pairs a skeletal muscle relaxant (orphenadrine citrate) with a non-opioid pain reliever (aspirin, an NSAID/salicylate) and a small amount of caffeine. It's FDA-approved as an add-on to rest and physical therapy for short-term relief of mild to moderate pain from acute musculoskeletal problems, such as muscle spasm or strain. It's meant for short-term use alongside physical therapy, not to treat the underlying cause of the spasm, and it isn't intended for chronic, everyday use.

The brand name most associated with this combination is Norgesic (and the higher-strength Norgesic Forte), though the brand has been discontinued in the US and the product is now sold generically; the name Orphengesic has also been used historically for the same combination.

Orphenadrine-aspirin-caffeine cost without insurance

Because this is a generic combination, it's typically less expensive than a branded product would be, but that doesn't mean every pharmacy charges the same amount. Cash prices for generic drugs can vary widely by pharmacy, even within the same city, so it's worth comparing before you fill. Rx.com pulls pricing from over 60,000 pharmacies nationwide so you can see how your local options stack up and choose where to fill your prescription.

There is no manufacturer savings card for this drug, since it's a generic combination product rather than a currently marketed brand. Enter your ZIP above to see today's price at pharmacies near you.

Alternatives and related muscle relaxants

If your doctor is treating muscle spasm or strain, orphenadrine-aspirin-caffeine is one of several muscle relaxants that may be considered. Related options include the orphenadrine-only product, orphenadrine, as well as other commonly prescribed skeletal muscle relaxants such as cyclobenzaprine, methocarbamol, and carisoprodol. Since this combination also contains aspirin, it's helpful to understand that ingredient on its own, covered on our aspirin page.

Which option is appropriate depends on your specific condition, other medications, and health history, so this comparison is for general information only, not a recommendation to switch — talk to your provider or pharmacist about what's right for you.

Safety information

This medication combines three active ingredients, so it carries several safety considerations. Because it contains aspirin, it should be avoided by people with an aspirin or NSAID allergy, active peptic ulcer or GI bleeding, or bleeding disorders, and it should not be given to children or teenagers with chickenpox or flu-like symptoms because of the risk of Reye's syndrome. The orphenadrine component should not be used by people with glaucoma, certain stomach or intestinal blockages (pyloric or duodenal obstruction, achalasia), an enlarged prostate with urinary blockage, myasthenia gravis, or cardiospasm, and it can cause anticholinergic effects like dry mouth, blurred vision, urinary retention, or a fast heartbeat. It can also cause drowsiness, so caution is advised with alcohol or other sedating medications, and the caffeine component may cause nervousness, trouble sleeping, or a faster heart rate.

Older adults may be more sensitive to these effects, and caution is warranted with kidney or liver problems. This medicine is intended for short-term use, not everyday long-term treatment. This is general information, not medical advice — talk with your doctor or pharmacist about whether it's right for you.