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Phenytoin Sodium Vial — prescription drug image

Phenytoin Sodium

Phenytoin Sodium 2ML of 50MG/ML

What is Phenytoin Sodium?

Phenytoin Sodium is an anticonvulsant medication primarily used to manage and prevent seizures in conditions such as epilepsy. It works by slowing down impulses in the brain that cause seizures. Phenytoin Sodium stabilizes the threshold against hyperexcitability caused by excessive stimulation or environmental changes capable of reducing neuronal excitability.

Prescription savings · · · ·

What is Phenytoin Sodium ?

Phenytoin Sodium is an anticonvulsant medication primarily used to manage and prevent seizures in conditions such as epilepsy. It works by slowing down impulses in the brain that cause seizures. Phenytoin Sodium stabilizes the threshold against hyperexcitability caused by excessive stimulation or environmental changes capable of reducing neuronal excitability.
  • Pain, changes in skin color, sores, peeling, or swelling at or near the injection site
  • Fast, slow, or pounding heartbeat, lightheadedness or fainting
  • Fever, chills, cough, sore throat, and body aches
  • Severe confusion, problems with balance or walking, slurred speech, tremors
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Fever, skin rash, or swollen glands in your armpits, neck, or groin
  • Unusual bleeding, bruising, or weakness
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash
  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, diabetes, heart disease, low blood pressure, or porphyria.
  • This medicine may cause the following problems:Serious skin reactions (may happen after treatment has stopped)Drug reaction with eosinophilia and systemic symptoms (DRESS), which may damage organs such as the liver, kidney, or heartLiver damageDecreased levels of blood cells, which may cause bleeding or increase your risk for infectionPurple glove syndrome, which may damage skin and tissues near the injection siteHigher blood sugar levels
  • This medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Fever, skin rash, or swollen glands in your armpits, neck, or groin
  • Pain, changes in skin color, sores, peeling, or swelling at or near the injection site
  • Severe confusion, problems with balance or walking, slurred speech, tremors
  • Unusual bleeding, bruising, or weakness
What is phenytoin sodium used for?
The extended-release capsule form is used to treat tonic-clonic (grand mal) and psychomotor (temporal lobe) seizures, and to prevent and treat seizures that occur during or after neurosurgery.
Is generic phenytoin as effective as Dilantin?
Generic phenytoin sodium extended-release capsules are FDA-approved and go through bioequivalence testing. That said, because phenytoin has a narrow therapeutic range, many doctors recommend staying on the same product consistently rather than switching between manufacturers, and your doctor may check blood levels after any change.
Can I stop taking phenytoin suddenly?
No. Stopping phenytoin abruptly can trigger a rebound increase in seizures or a dangerous condition called status epilepticus. Any dose reduction or discontinuation should be done gradually and under your doctor's direction.
Does phenytoin sodium interact with other medications?
Yes, phenytoin has many potential drug interactions because it affects liver enzymes that metabolize other medications, and other drugs can affect phenytoin blood levels in turn. Tell your doctor and pharmacist about everything you take, including other seizure medications, blood thinners, and hormonal birth control.
How much does Phenytoin Sodium cost without insurance?
The price of Phenytoin Sodium without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Phenytoin Sodium?
Common side effects of Phenytoin Sodium may include: Pain, changes in skin color, sores, peeling, or swelling at or near the injection site, Fast, slow, or pounding heartbeat, lightheadedness or fainting, Fever, chills, cough, sore throat, and body aches, Severe confusion, problems with balance or walking, slurred speech, tremors, Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Phenytoin Sodium?
Generic versions may be available for Phenytoin Sodium. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Phenytoin Sodium on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Phenytoin Sodium?
The cheapest pharmacy for Phenytoin Sodium depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Phenytoin Sodium near you.

Phenytoin Sodium Coupons & Prices

Phenytoin Sodium 2ML of 50MG/ML

Phenytoin Sodium Vial — prescription drug image
Prescription
Phenytoin Sodium 2ml of 50mg/ml (1)
your area ·

Phenytoin Sodium prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
2ml of 50mg/ml · Vial 4 $5.98
5ml of 50mg/ml · Vial 40 $172.00 $17.62

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Phenytoin sodium is a long-used anticonvulsant, sold under the brand name Dilantin and also available as a generic extended-release capsule, and it's a common search as a "phenytoin sodium coupon." Cash prices for this prescription can vary quite a bit from pharmacy to pharmacy, so it's worth comparing before you fill it. Enter your ZIP above to see today's price near you.

What is phenytoin sodium and how does it work?

Phenytoin sodium is an anti-seizure (anticonvulsant) medication that works by stabilizing electrical activity in the brain, which helps prevent the spread of seizure activity. The extended-release capsule form is FDA-approved for tonic-clonic (grand mal) and psychomotor (temporal lobe) seizures, and for preventing and treating seizures that occur during or after neurosurgery.

Because phenytoin has a narrow therapeutic range, meaning the difference between an effective dose and a dose that causes side effects can be small, doctors typically monitor blood levels and keep patients on a consistent product and dosing schedule.

Comparing generic and brand pricing

Generic phenytoin sodium extended-release capsules are widely available and are typically far less expensive out of pocket than the brand-name Dilantin. Because this is a generic drug, prices can still vary significantly by pharmacy for the same prescription. Rx.com compares pricing across 60,000+ pharmacies so you can find where it costs less near you, whether you're paying cash, have a high deductible, or your plan's copay is high.

  • Ask your pharmacist to fill the same manufacturer's product each time you refill, since your doctor may want consistency for a narrow-therapeutic-index drug like this
  • Compare cash prices even if you have insurance, since some pharmacy cash prices beat the copay

Alternatives and related seizure medications

Other anticonvulsants your doctor may consider depending on your seizure type and history include carbamazepine, valproic-acid products, and levetiracetam. Switching between phenytoin products, or between phenytoin and another anticonvulsant, should always be done under a doctor's supervision, since a change can affect seizure control.

Safety information

Phenytoin is contraindicated in people with a known hypersensitivity to phenytoin or other hydantoin medications. It can rarely cause serious skin reactions, including Stevens-Johnson syndrome; the risk is higher in people of Asian ancestry who carry the HLA-B*1502 gene variant, and your doctor may test for this before starting treatment. Stopping phenytoin suddenly can trigger worsening seizures or status epilepticus, so any dose changes should be gradual and doctor-directed. Like other anti-seizure medicines, phenytoin carries a warning about a small increased risk of suicidal thoughts or behavior; tell your doctor about any mood changes. This is general information, not medical advice — talk to your provider about your specific situation.

Sources & accuracy

This Phenytoin Sodium information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Phenytoin Sodium on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.