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Plenity Package — prescription drug image

Plenity

Plenity 168 Capsules

Prescription weight loss

Weight-loss medication, prescribed online

$99

Licensed U.S. providers · No insurance needed · Shipped to your door

See if I qualify Free online visit · No commitment
Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

What is Plenity?

Plenity, approved by the FDA, is an innovative weight management treatment designed for adults with a body mass index (BMI) of 25 to 40. It functions by creating a sense of fullness, as its capsules release absorbent particles in the stomach that expand, helping to control appetite and food intake without the use of stimulants or systemic medications.

Prescription savings · · · ·

What is Plenity ?

Plenity, approved by the FDA, is an innovative weight management treatment designed for adults with a body mass index (BMI) of 25 to 40. It functions by creating a sense of fullness, as its capsules release absorbent particles in the stomach that expand, helping to control appetite and food intake without the use of stimulants or systemic medications.
  • Bloating
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Should not be used by pregnant or nursing mothers without medical advice
  • Not intended for use by individuals under 18 years of age
  • Consult a healthcare provider before starting any new treatment
  • May cause allergic reactions in people sensitive to components of the product
Is Plenity a drug or a device?
Plenity is FDA-cleared as a medical device, not a drug. It works mechanically by absorbing water and expanding in the stomach rather than through systemic drug action.
Do you need a prescription for Plenity?
Yes. Plenity requires a prescription and is dispensed through a limited pharmacy network rather than being available over the counter at any pharmacy.
Is there a generic version of Plenity?
No. Plenity is a single-source, FDA-cleared product, so there isn't an FDA-approved generic equivalent.
What BMI qualifies someone for Plenity?
Plenity is cleared to help with weight management, along with diet and exercise, in adults with a BMI of 25 to 40.
How is Plenity different from GLP-1 weight-loss medications?
Plenity is a non-systemic hydrogel that creates fullness by physically expanding in the stomach, while GLP-1 medications like semaglutide work by affecting appetite-regulating hormones after being absorbed into the body. Talk with a healthcare provider about which approach fits your situation.
How much does Plenity cost without insurance?
The price of Plenity without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Plenity?
Common side effects of Plenity may include: Bloating, Diarrhea, Abdominal pain, Flatulence. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Plenity?
Generic versions may be available for Plenity. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Plenity on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Plenity?
The cheapest pharmacy for Plenity depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Plenity near you.

Plenity Coupons & Prices

Plenity 168 Capsules

Prescription weight loss

Weight-loss medication, prescribed online

$99

Licensed U.S. providers · No insurance needed · Shipped to your door

See if I qualify Free online visit · No commitment
Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.
Plenity Package — prescription drug image
Prescription
Plenity 168 capsules (1)
your area ·
Prescription weight loss

Weight-loss medication, prescribed online

Licensed U.S. providers · No insurance needed · Shipped to your door

$99
See if I qualify Free online visit · No commitment
Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Plenity prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
168 capsules · Package 168 $131.99 $100.84

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Plenity is a prescription-only, FDA-cleared weight management aid taken as capsules before meals. It's a single-source product with no generic equivalent, and it's dispensed through specific pharmacy networks rather than every local pharmacy, so a Plenity coupon can still help you find the lowest price available near you — enter your ZIP above to check today's price.

What Is Plenity and How Does It Work

Plenity (cellulose and citric acid) is an FDA-cleared, non-systemic superabsorbent hydrogel taken as capsules with water before lunch and dinner. Once swallowed, the hydrogel particles absorb water and expand in the stomach and small intestine, taking up space and mixing with food to help create a feeling of fullness, then pass through the digestive system. It's cleared to aid in weight management, along with diet and exercise, in adults with a BMI of 25-40.

Manufacturer Program vs. an Rx.com Cash Coupon

Plenity does not have a widely available FDA-approved generic, since it's a single-source cleared product rather than a small-molecule drug with an Orange Book listing. There isn't a well-documented manufacturer copay card for Plenity the way there is for many brand-name prescription drugs, and it's dispensed through a limited pharmacy network rather than filled at any local pharmacy. Because of that, comparing what different participating pharmacies charge in cash, and using a coupon where accepted, is one of the more reliable ways to manage the cost, especially if you don't have insurance coverage for it.

Comparisons and Alternatives

Plenity is sometimes compared with other prescription weight-management options, including GLP-1 medications like semaglutide and tirzepatide, which work differently (as appetite-regulating hormones) rather than as a physical fullness-inducing hydrogel. Plenity's non-systemic mechanism means it isn't absorbed into the bloodstream, which is a meaningful difference for people weighing their options with a healthcare provider.

Safety Information

Plenity shouldn't be used by people who are pregnant, or who have a history of esophageal strictures, anatomic esophageal abnormalities (such as webs, diverticuli, or rings), or complications from prior gastrointestinal surgery. It should be used with caution in people with active gastroesophageal reflux, peptic ulcer disease, or frequent heartburn. This is general information, not medical advice — talk to your prescriber about whether Plenity is appropriate for you.

Sources & accuracy

This Plenity information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Plenity on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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