Prednisone
Prednisone
What is Prednisone?
Prednisone is a prescription corticosteroid used to treat a wide range of inflammatory, allergic, and autoimmune conditions. It helps reduce inflammation and suppress the immune system, providing relief for conditions such as asthma, arthritis, lupus, severe allergies, and certain skin disorders.
Side Effects
- Fever, chills, cough, sore throat, and body aches
- Severe stomach pain, nausea, vomiting, or red or black stools
- Trouble seeing, eye pain, headache
Warnings
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding or if you have kidney problems, heart failure, high blood pressure, a recent heart attack, diabetes, glaucoma, osteoporosis, or thyroid problems. Tell your doctor about any infection you have. Also tell your doctor if you have had mental or emotional problems (such as depression) or stomach or bowel problems (such as an ulcer or diverticulitis).
- This medicine may cause the following problems:Mood or behavior changesHigher blood pressure, retaining water, changes in salt or potassium levels in your bodyCataracts or glaucoma (with long-term use)Weak bones or osteoporosis (with long-term use)Slow growth in children (with long-term use)Muscle problems (with high doses, especially if you have myasthenia gravis or similar nerve and muscle problems)
- This medicine may raise your blood sugar level, especially in people with diabetes.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
Prescription savings · · · ·
What is Prednisone ?
Prednisone is a prescription corticosteroid used to treat a wide range of inflammatory, allergic, and autoimmune conditions. It helps reduce inflammation and suppress the immune system, providing relief for conditions such as asthma, arthritis, lupus, severe allergies, and certain skin disorders.
- Fever, chills, cough, sore throat, and body aches
- Severe stomach pain, nausea, vomiting, or red or black stools
- Trouble seeing, eye pain, headache
- Rapid weight gain, swelling in your hands, ankles, or feet
- Skin changes or growths
- Muscle pain or weakness
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Dark freckles, skin color changes, coldness, weakness, tiredness, nausea, vomiting, weight loss
- Depression, unusual thoughts, feelings, or behaviors, trouble sleeping
- Increased hunger or thirst, increase in how much or how often you urinate
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding or if you have kidney problems, heart failure, high blood pressure, a recent heart attack, diabetes, glaucoma, osteoporosis, or thyroid problems. Tell your doctor about any infection you have. Also tell your doctor if you have had mental or emotional problems (such as depression) or stomach or bowel problems (such as an ulcer or diverticulitis).
- This medicine may cause the following problems:Mood or behavior changesHigher blood pressure, retaining water, changes in salt or potassium levels in your bodyCataracts or glaucoma (with long-term use)Weak bones or osteoporosis (with long-term use)Slow growth in children (with long-term use)Muscle problems (with high doses, especially if you have myasthenia gravis or similar nerve and muscle problems)
- This medicine may raise your blood sugar level, especially in people with diabetes.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
- This medicine could cause you to get infections more easily. Tell your doctor right away if you are exposed to chicken pox, measles, or other serious infection. Tell your doctor if you had a serious infection in the past, such as tuberculosis or herpes.
- Tell your doctor about any extra stress or anxiety in your life. Your dose might need to be changed for a short time.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Prednisone Coupons & Prices
Prednisone
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Prednisone prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 1mg · Tablet | 120 | $35.99 | $15.37 |
| 2.5mg · Tablet | 30 | $12.69 | $7.13 |
| 5mg · Tablet | 10 | $11.99 | $5.60 |
| 10mg · Tablet | 10 | $11.99 | $4.57 |
| 20mg · Tablet | 10 | $11.99 | $6.15 |
| 50mg · Tablet | 10 | — | $8.05 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
Looking for a prednisone coupon? Prednisone is a widely used generic corticosteroid, and because it's generic it's already one of the more affordable prescriptions - but the cash price still varies a lot from one pharmacy to the next, sometimes for the very same tablet. Rx.com lets you compare prednisone prices across more than 60,000 pharmacies and pull a free discount coupon you can use at the counter, whether or not you have insurance. Enter your ZIP above to see today's price near you.
What is prednisone and how does it work?
Prednisone is a corticosteroid - specifically a glucocorticoid - that works as a systemic anti-inflammatory and immunosuppressant. In plain terms, it calms down inflammation and quiets an overactive immune response, which is why it's prescribed across so many different conditions. It's FDA-approved for a broad range of uses, including rheumatic conditions like rheumatoid arthritis and acute gout, autoimmune and collagen diseases such as lupus, severe allergic reactions, asthma and COPD flare-ups, certain skin conditions, some blood disorders, inflammatory bowel disease (ulcerative colitis and Crohn's), and hormone (endocrine) disorders.
Prednisone is available as a low-cost generic. It's also very commonly prescribed as a short "steroid taper" - a brief course at a decreasing dose - to settle an acute inflammatory flare. Your provider decides the dose and how long you take it based on your condition.
Prednisone cost and how to save without insurance
Because prednisone is generic, it's usually inexpensive compared with brand-name drugs - but "inexpensive" doesn't mean the price is the same everywhere. Cash prices for the exact same strength and quantity can differ widely between pharmacies, which is exactly why comparing before you fill is worth the few seconds it takes. If you're paying without insurance, or if a discount coupon beats your copay, a free Rx.com coupon can help.
Rx.com compares live prednisone prices across 60,000+ pharmacies so you can see where it's cheapest near you and grab a coupon at no cost. Enter your ZIP above to see today's price. There is no manufacturer savings card for generic prednisone - the savings come from comparing pharmacy cash prices and using a discount coupon.
Prednisone alternatives and related corticosteroids
Prednisone belongs to a family of corticosteroids that treat similar problems but differ in strength, how long they last, and how the body processes them. Your prescriber chooses among them based on your condition and needs. Related medications include prednisolone, methylprednisolone, dexamethasone, and hydrocortisone.
There is also a delayed-release form of prednisone sold under the brand name Rayos; older brands such as Deltasone, Sterapred, and Prednicot are largely discontinued, and standard immediate-release prednisone is what most people fill as a generic. You can compare prices on any of these on Rx.com. Only your provider can decide which corticosteroid is right for you - don't switch on your own.
Prednisone safety and important warnings
Prednisone has no boxed warning, but there are important things to know. Because it suppresses the immune system, it can increase your risk of infection and may mask the usual signs of one; live vaccines should generally be avoided while taking immunosuppressive doses. It's not used in people with a systemic (bodywide) fungal infection or a known allergy to it. Longer-term use carries risks such as higher blood sugar, raised blood pressure, fluid retention, bone thinning (osteoporosis), cataracts or glaucoma, stomach ulcers, muscle weakness, mood or sleep changes, and slowed growth in children.
One key point: after taking prednisone for a prolonged period, don't stop it abruptly. Your body needs a gradual taper to avoid adrenal problems - your provider will guide this. This is general information, not medical advice. Talk with your doctor or pharmacist about your dose, your other medications, and any side effects you notice.
This Prednisone information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Prednisone on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
Prednisone — Articles & Guides
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.