Pyridostigmine Bromide Er Coupons & Prices

Pyridostigmine bromide extended-release tablets are the generic form of an extended-release cholinesterase inhibitor used to manage myasthenia gravis, sold under the brand name Mestinon Timespan. Because this is a generic drug, prices can vary a lot from one pharmacy to the next. If you're looking for a pyridostigmine bromide ER coupon, enter your ZIP above to compare prices at pharmacies near you before you fill.

What is pyridostigmine bromide ER and how does it work?

Pyridostigmine bromide is a cholinesterase inhibitor used for the symptomatic treatment of myasthenia gravis, a chronic autoimmune condition that causes muscle weakness. It works by blocking the breakdown of acetylcholine, the chemical messenger that signals muscles to contract, which helps improve muscle strength and function. The extended-release (Timespan) tablet is a wax-matrix formulation designed to release the medication slowly, and it's typically taken at bedtime to help control weakness overnight and in the early morning.

The extended-release tablet must be swallowed whole. Crushing, splitting, or chewing it can release the full dose at once instead of gradually.

Comparing prices without insurance

Pyridostigmine bromide extended-release tablets are made by several generic manufacturers, and cash prices for the same generic drug can differ significantly between pharmacies in the same town. Rx.com compares prices across more than 60,000 U.S. pharmacies, so whether you have insurance, a high deductible, or no coverage at all, you can see which pharmacy has the lowest price today. Enter your ZIP code above and search for pyridostigmine bromide ER to compare.

Regular-release pyridostigmine and other myasthenia gravis treatments

Pyridostigmine is also available as an immediate-release tablet and an oral solution, which some patients use during the day alongside the extended-release tablet at night; these are different products with different dosing schedules, and switching between forms should only be done with your prescriber's guidance. For patients whose symptoms aren't adequately controlled on pyridostigmine alone, doctors may add other myasthenia gravis therapies, including immunosuppressants or newer targeted biologic treatments. Talk to your neurologist about what combination is right for you.

Safety information

Pyridostigmine should not be used if you have a mechanical intestinal or urinary tract obstruction. Tell your doctor about any history of asthma, heart disease, or kidney problems, since dose adjustments may be needed. Taking too much pyridostigmine can cause a cholinergic crisis, with symptoms like increased weakness, excessive salivation, sweating, nausea, or slowed heart rate; this is a medical emergency. Because too little medication can also cause worsening muscle weakness that can look similar, never change your dose without talking to your prescriber first. This information is not a substitute for medical advice — always follow your doctor's instructions.