Telmisartan-Amlodipine Coupons & Prices

A telmisartan-amlodipine coupon from Rx.com can lower what you pay at the pharmacy counter for this two-in-one blood pressure tablet, which combines telmisartan (an angiotensin II receptor blocker) with amlodipine (a calcium channel blocker). The brand version, Twynsta, is no longer marketed in the United States, so what you fill today is the FDA-approved generic. Cash prices for the same tablet and quantity can differ a lot from one pharmacy to the next, even between stores a few blocks apart, so it is worth comparing before you fill. Enter your ZIP code above to see today's price near you across our network of more than 60,000 participating pharmacies, then show the free coupon at the counter.

What is telmisartan and amlodipine, and how does it work?

Telmisartan and amlodipine is a fixed-dose combination tablet that is FDA-approved to treat high blood pressure (hypertension) in adults. Lowering blood pressure reduces the risk of cardiovascular events such as strokes and heart attacks. It pairs two medicines that lower blood pressure in different ways: telmisartan is an angiotensin II receptor blocker (ARB) that relaxes blood vessels by blocking a hormone signal that tightens them, and amlodipine besylate is a dihydropyridine calcium channel blocker (CCB) that relaxes the muscle in blood vessel walls.

It can be used alone or alongside other blood pressure medicines. A doctor may start it as initial therapy in someone likely to need more than one drug to reach their goal, or add it (or switch to it) for a person who is not controlled on telmisartan or amlodipine alone, or who had a dose-limiting side effect such as swelling on one component by itself. It comes as 40/5, 40/10, 80/5, and 80/10 mg tablets. Despite containing amlodipine, this combination is approved only for high blood pressure — it is not approved to treat angina, even though amlodipine on its own is.

What telmisartan-amlodipine costs without insurance, and how to pay less

Because Twynsta is no longer marketed in the U.S., there is no brand-versus-generic decision to make here and no manufacturer savings card for this combination. If you are paying cash, the price you are quoted is set by the individual pharmacy, and those cash prices vary widely from store to store for the exact same generic tablet, strength, and day supply. That variation is the main thing you control, which is why comparing before you fill matters more than it might seem.

Rx.com compares prices at more than 60,000 pharmacies nationwide and gives you a free discount coupon you can use whether or not you have insurance. A few practical tips: check the price for the strength your prescriber wrote, ask about a 90-day supply if you take it long term, and compare the coupon price against your insurance copay, since one is sometimes lower than the other. Enter your ZIP above to see today's price at pharmacies near you.

Alternatives and related blood pressure medicines

If your prescriber is weighing options, several related medicines work on the same pathways. Only your prescriber can decide what fits your situation, but these are the ones most often compared:

• The individual components on their own: telmisartan and amlodipine.
• Other ARBs: olmesartan and losartan.
• Other combination tablets: telmisartan and hydrochlorothiazide (an ARB plus a diuretic), amlodipine and valsartan, and amlodipine and benazepril.

Do not switch products or split a combination tablet into separate pills on your own. Prices differ across all of these, so if your prescriber says more than one option is reasonable, it is fair to ask which is cheapest for you and compare each here first.

Safety information you should know

Telmisartan and amlodipine carries a boxed warning for fetal toxicity: medicines that act on the renin-angiotensin system can injure or kill a developing baby. If you become pregnant, stop the medicine and tell your doctor right away. Other important risks include low blood pressure with dizziness or fainting (especially if you are dehydrated or salt-depleted, such as on a high-dose diuretic), high potassium, and reduced kidney function in people whose kidneys depend on this hormone system, such as those with narrowed kidney arteries, heart failure, or volume depletion. It should not be combined with aliskiren in people with diabetes, and dual blockade with an ACE inhibitor is generally avoided. From the amlodipine part, swelling of the ankles and feet is dose-related, and rarely people with severe blockage in the heart arteries have had worse angina or a heart attack when starting or increasing the dose.

Liver problems and biliary obstruction call for extra caution. Because the lowest available combination tablet is 40/5 mg, the label says initial therapy with the combination tablet is not recommended in people with hepatic impairment; instead, the components are titrated separately (starting amlodipine at the low end of its range, or adding amlodipine 2.5 mg to telmisartan). Telmisartan is not recommended in severe liver impairment.

The most common side effects reported in studies were swelling (peripheral edema), dizziness, and back pain. Tell your prescriber and pharmacist about everything you take, since interactions include lithium (levels can rise), NSAIDs (can blunt the blood pressure effect and strain the kidneys), potassium supplements and potassium-sparing diuretics, digoxin, simvastatin (limit to 20 mg a day with amlodipine), and CYP3A4 inhibitors. This page is general information, not medical advice. Talk with your doctor or pharmacist about your own situation, and read the label that comes with your prescription.