Topicaine 5
Topicaine 5 30GM of 5%
What is Topicaine 5?
Topicaine 5 is a topical anesthetic gel that contains 5% lidocaine, specifically formulated to provide temporary relief of local discomfort, pain, and itching associated with minor burns, cuts, or skin irritations. It is preferred for its non-oily consistency and its efficacy in numbing the skin before minor dermatological procedures, enhancing patient comfort.Side Effects
- Tremor or seizures
- Confusion, dizziness, drowsiness, lightheadedness
- Blurred or double vision
Warnings
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Do not use a heating pad, electric blanket, or any other heat source over the patch. However, you may apply Ztlido® patch on the skin after exposure to a moderate heat setting.
- Call your doctor if your symptoms do not improve or if they get worse.
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart problems, lung or breathing problems, porphyria (enzyme problem), a blood disorder, G6PD, or epilepsy.
- This medicine may cause methemoglobinemia (blood disorder).
Prescription savings · · · ·
What is Topicaine 5 ?
Topicaine 5 is a topical anesthetic gel that contains 5% lidocaine, specifically formulated to provide temporary relief of local discomfort, pain, and itching associated with minor burns, cuts, or skin irritations. It is preferred for its non-oily consistency and its efficacy in numbing the skin before minor dermatological procedures, enhancing patient comfort.- Tremor or seizures
- Confusion, dizziness, drowsiness, lightheadedness
- Blurred or double vision
- Slow, fast, or uneven heartbeat
- Troubled or shallow breathing, trouble swallowing
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Pale, gray, or blue lips, nails, or skin, dark urine, headache, unusual tiredness or weakness
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Do not use a heating pad, electric blanket, or any other heat source over the patch. However, you may apply Ztlido® patch on the skin after exposure to a moderate heat setting.
- Call your doctor if your symptoms do not improve or if they get worse.
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart problems, lung or breathing problems, porphyria (enzyme problem), a blood disorder, G6PD, or epilepsy.
- This medicine may cause methemoglobinemia (blood disorder).
- Do not give lidocaine solution to a child younger than 3 years of age for teething pain, unless your doctor says it is okay.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Topicaine 5 Coupons & Prices
Topicaine 5 30GM of 5%
Topicaine 5 is an over-the-counter topical gel containing 5% lidocaine, a numbing (anesthetic) ingredient. It doesn't require a prescription, but if your pharmacy stocks it or your provider recommends it as part of a procedure, enter your ZIP above to see today's price and find a Topicaine 5 coupon nearby.
What is Topicaine 5 and how does it work?
Topicaine 5 gel contains lidocaine 5%, a local anesthetic that temporarily numbs the skin by blocking nerve signals in the area where it's applied. It's registered as an over-the-counter external analgesic gel, labeled for the temporary relief of pain and itching due to minor anorectal irritation. In practice, topical lidocaine gels like this are also widely used off-label to numb skin before minor cosmetic or aesthetic procedures, such as tattooing, piercing, laser hair removal, or microneedling — always follow the product label and any instructions from the professional performing the procedure.
Saving on Topicaine 5
Because it's sold over the counter, Topicaine 5 pricing can still vary noticeably between pharmacies and online retailers depending on tube size and where it's purchased. If your pharmacy carries it, comparing prices or using a coupon at checkout can lower what you pay out of pocket.
Topicaine 5 vs. other topical anesthetics
- Topicaine (4%) is the same brand's lower-strength lidocaine gel.
- Lidocaine-prilocaine cream (EMLA and generics) combines two anesthetics and is another topical numbing option, often used before minor skin procedures or injections.
- Benzocaine gels are a different topical anesthetic, more commonly used for minor mouth or throat irritation rather than skin numbing.
Safety information
Topicaine 5 is for external use only — avoid contact with the eyes, and do not insert it into the rectum. Don't use it on raw or blistered skin or apply more than directed, since absorbing too much lidocaine through the skin can cause side effects. Stop use and check with a doctor if irritation, rash, or bleeding occurs, or if symptoms don't improve within 7 days. Keep it away from children and away from heat or flame, as the gel is flammable. This is general information, not medical advice — ask a pharmacist or provider if you're unsure whether it's appropriate for your situation.
This Topicaine 5 information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Topicaine 5 on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.