What is Tramadol Hcl (Er Biphasic) ?

Tramadol HCl (ER biphasic) is an extended-release formulation used for the management of moderate to severe pain requiring continuous, long-term treatment. Its biphasic release mechanism provides initial rapid analgesia followed by a sustained release to maintain consistent plasma levels over 24 hours, enhancing patient compliance and comfort. It should be used with caution, adhering strictly to prescribed dosages due to potential risks of dependency and adverse effects.

• Trouble breathing
• Blue lips, fingernails, or skin
• Changes in skin color, dark freckles, cold feeling, tiredness, weight loss
• Blistering, peeling, red skin rash
• Anxiety, restlessness, fast heartbeat, fever, muscle spasms, nausea, vomiting, diarrhea, seeing or hearing things that are not there
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Extreme dizziness, drowsiness, or weakness, shallow breathing, slow heartbeat, seizures, and cold, clammy skin
• Shaking, trembling, sweating, hunger, confusion
• Lightheadedness, dizziness, fainting
• Weakness, muscle twitching
• Worsening of pain, increased sensitivity to pain
• Unusual mood or behavior, thoughts of killing yourself or others
• Worsening of pain, increased sensitivity to pain

• This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.
• Tell any doctor or dentist who treats you that you are using this medicine.
• Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
• This medicine may cause the following problems:High risk of overdose, which can lead to deathRespiratory depression (serious breathing problem that can be life-threatening)Sleep-related breathing problems (including sleep apnea, sleep-related hypoxemia)Worsening of painSerotonin syndrome (when used with certain medicines)Increased risk of seizuresAdrenal gland problemLow blood pressureUnusual change in mood or behaviorHypoglycemia (low blood sugar level)
• This medicine may make you dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Sit or lie down if you feel dizzy. Stand up carefully.
• This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.
• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease (including cirrhosis), adrenal problems, gallstones, lung or breathing problems (including sleep apnea), diabetes, pancreas problems, or a history of head injury, seizures, drug addiction, or depression or similar emotional problems. Tell your doctor if you have phenylketonuria.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.
• This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.