Voquezna Triple Pak
Voquezna Triple Pak 112 Therapy Pack
What is Voquezna Triple Pak?
The Voquezna Triple Pak is a pharmaceutical combination used to treat Helicobacter pylori infection and duodenal ulcer disease. This medication pack contains three components: vonoprazan, a potent acid blocker; amoxicillin, an antibiotic; and clarithromycin, a macrolide antibiotic, which work together to eradicate H. pylori bacteria and promote ulcer healing. Always use this medication under the guidance of a healthcare professional to ensure safety and effectiveness.Side Effects
- Severe diarrhea, stomach pain or cramps
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Severe muscle pain or weakness
Warnings
- Tell your doctor if you have kidney disease, liver disease, heart rhythm problems, nerve or muscle problem (including myasthenia gravis), or any kind of infection.
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
- This medicine may cause drowsiness, trouble with thinking, or trouble with controlling body movements. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Tell your doctor if you are breastfeeding. Your doctor may tell you to pump and throw away your breast milk during treatment and for 2 days after the last dose.
Prescription savings · · · ·
What is Voquezna Triple Pak ?
The Voquezna Triple Pak is a pharmaceutical combination used to treat Helicobacter pylori infection and duodenal ulcer disease. This medication pack contains three components: vonoprazan, a potent acid blocker; amoxicillin, an antibiotic; and clarithromycin, a macrolide antibiotic, which work together to eradicate H. pylori bacteria and promote ulcer healing. Always use this medication under the guidance of a healthcare professional to ensure safety and effectiveness.- Severe diarrhea, stomach pain or cramps
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Severe muscle pain or weakness
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Itching or discharge in the vagina
- Fainting, dizziness, lightheadedness
- Fast, pounding, or uneven heartbeat
- Blistering, peeling, red skin rash
- Tell your doctor if you have kidney disease, liver disease, heart rhythm problems, nerve or muscle problem (including myasthenia gravis), or any kind of infection.
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
- This medicine may cause drowsiness, trouble with thinking, or trouble with controlling body movements. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Tell your doctor if you are breastfeeding. Your doctor may tell you to pump and throw away your breast milk during treatment and for 2 days after the last dose.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- This medicine may cause the following problems:Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS)Heart rhythm problems, including QT prolongation and torsades de pointesLiver problemsIncreased risk of bleedingHypoglycemia (low blood sugar)Myasthenia gravis (severe muscle weakness)
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Call your doctor if your symptoms do not improve or if they get worse.
- Some men who use this medicine have become infertile (unable to have children). Talk with your doctor before using this medicine if you plan to have children.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Voquezna Triple Pak Coupons & Prices
Voquezna Triple Pak 112 Therapy Pack
Voquezna Triple Pak is a co-packaged prescription treatment for H. pylori infection, and if your doctor has prescribed it, a Voquezna Triple Pak coupon from Rx.com can help you find the lowest price at a nearby pharmacy for this 14-day regimen. Enter your ZIP above to see today's price.
What Is Voquezna Triple Pak and How Does It Work?
Voquezna Triple Pak is a co-packaged, brand-name treatment for Helicobacter pylori (H. pylori) infection in adults. It combines vonoprazan (a potassium-competitive acid blocker), amoxicillin (a penicillin-class antibiotic), and clarithromycin (a macrolide antibiotic), taken together twice daily for 14 days. Vonoprazan suppresses stomach acid to help create conditions where the two antibiotics can more effectively clear the H. pylori bacteria.
Manufacturer Savings Card vs. an Rx.com Cash Coupon
Phathom Pharmaceuticals, the maker of Voquezna Triple Pak, offers an official savings program for eligible patients; terms and eligibility vary, so check the current program directly through Phathom or your prescriber. Manufacturer copay cards are generally limited to patients with commercial insurance and typically can't be used with Medicare or Medicaid. An Rx.com cash coupon isn't tied to insurance status, so it can help if you're uninsured, on Medicare, or if the manufacturer card is declined.
As a co-packaged combination product, Voquezna Triple Pak does not currently have an FDA-approved generic equivalent marketed in the US, so comparing pharmacy cash prices is often the most direct way to manage cost.
Alternatives and Related Treatments
- Traditional H. pylori regimens combine a proton pump inhibitor (such as omeprazole) with antibiotics like amoxicillin and clarithromycin, taken as separate prescriptions rather than a co-package.
- Voquezna Dual Pak (vonoprazan plus amoxicillin, without clarithromycin) is another option your doctor may consider, particularly for patients with macrolide allergy or resistance concerns.
- Your doctor will choose the specific regimen based on your health history and local antibiotic resistance patterns.
Safety Information
Voquezna Triple Pak should be avoided in patients with a history of severe allergic reaction to penicillin antibiotics, and your doctor should ask about prior reactions to penicillins, cephalosporins, or macrolide antibiotics before you start. Clarithromycin can interact with a number of medications and should generally be avoided in patients with certain heart rhythm conditions (QT prolongation) or those taking other QT-prolonging drugs. Discontinue and contact your doctor if signs of liver problems (such as jaundice) develop. This is general information, not medical advice; talk with your doctor or pharmacist about your specific medications and health history before starting treatment.
This Voquezna Triple Pak information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Voquezna Triple Pak on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
Related Drugs
Browse more medications: starting with V · full A-Z directory · by condition · common drugs
Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.