Acetazolamide
acetaZOLAMIDE 250MG
What is Acetazolamide?
Acetazolamide is a generic drug used to treat patients with glaucoma; it is also used to treat patients with epilepsy and edema. The average Acetazolamide price is about $138 for a supply of 60, 250 mg tablets. However, you can use our free Rx.com coupon card to save significantly on Acetazolamide prices at a participating pharmacy near you.Side Effects
- Unusual bleeding or bruising
- Unusual bleeding, bruising, or weakness
- Pain in joints or lower back
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have lung problems.
- This medicine may cause the following problems:Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysisLiver problemsKidney stones
- This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
- This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
Prescription savings · · · ·
What is Acetazolamide ?
Acetazolamide is a generic drug used to treat patients with glaucoma; it is also used to treat patients with epilepsy and edema. The average Acetazolamide price is about $138 for a supply of 60, 250 mg tablets. However, you can use our free Rx.com coupon card to save significantly on Acetazolamide prices at a participating pharmacy near you.- Unusual bleeding or bruising
- Unusual bleeding, bruising, or weakness
- Pain in joints or lower back
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Change in how much or how often you urinate, lower back or side pain, painful or difficult urination
- Confusion, drowsiness
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Trouble breathing, tiredness, uneven heartbeat
- Tell your doctor if you are pregnant or breastfeeding, or if you have lung problems.
- This medicine may cause the following problems:Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysisLiver problemsKidney stones
- This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
- This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Unusual bleeding or bruising
- Pain in joints or lower back
Acetazolamide Coupons & Prices
acetaZOLAMIDE 250MG
Acetazolamide is a carbonic anhydrase inhibitor tablet prescribed for a range of uses including certain types of glaucoma, fluid retention (edema), some seizure disorders, and prevention of altitude sickness. It's only available as a generic in the U.S., and cash prices for it can vary a lot from one pharmacy to the next. Enter your ZIP above to compare an acetazolamide coupon across pharmacies near you.
What Is Acetazolamide and How Does It Work?
Acetazolamide is a sulfonamide-derivative carbonic anhydrase inhibitor. Depending on where it acts in the body, it can reduce fluid pressure in the eye (used for certain glaucomas), increase fluid and salt elimination through the kidneys (used as an add-on treatment for edema from congestive heart failure or from other drugs), help control certain seizure types as an adjunct to other seizure medicines, and reduce the fluid shifts that contribute to acute mountain sickness symptoms in people ascending to high altitude. It's taken by mouth as an immediate-release tablet, generally on a schedule your prescriber sets for your specific condition.
Why Prices Vary and How to Save
Acetazolamide is sold only as a generic; the older brand, Diamox, is no longer marketed in the U.S. Because it's a widely produced generic, cash prices can differ significantly by pharmacy, so it's worth comparing before you fill. Rx.com compares prices at more than 60,000 pharmacies to help you find a lower price near you, regardless of whether you have insurance.
Alternatives and Related Medications
For eye pressure, other options your provider may consider include methazolamide, an oral carbonic anhydrase inhibitor, or dorzolamide, a carbonic anhydrase inhibitor delivered as eye drops rather than a pill. For fluid retention, other classes of diuretics such as furosemide are sometimes used instead, though they work differently. Which option makes sense depends on your specific diagnosis, so this isn't a substitute for your prescriber's guidance.
Safety Information
Acetazolamide shouldn't be used by people with a sulfonamide allergy, low sodium or potassium levels, adrenal gland failure, severe kidney or liver disease, or certain types of acidosis, and it isn't meant for long-term use in some chronic angle-closure glaucoma. Taking high-dose aspirin together with acetazolamide has been associated with serious reactions including severe acidosis, so tell your provider about all medications you take, including aspirin. Common side effects can include tingling in the fingers/toes, taste changes, and increased urination. This is general information, not medical advice — talk with your provider about whether acetazolamide is right for you.
This Acetazolamide information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Acetazolamide on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.