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Apidra

Apidra 10ML of 100UNIT/ML

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What is Apidra?

Apidra is an insulin used to treat diabetes. There is not a generic version available. The average Apidra price can be quite expensive at about $334 for one 10 mL vial of Apidra. You can lower your high Apidra cost by up to 80% by using our free Apidra savings card at a local pharmacy that participates with Rx.com.

Prescription savings · · · ·

What is Apidra ?

Apidra is an insulin used to treat diabetes. There is not a generic version available. The average Apidra price can be quite expensive at about $334 for one 10 mL vial of Apidra. You can lower your high Apidra cost by up to 80% by using our free Apidra savings card at a local pharmacy that participates with Rx.com.
  • Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Dry mouth, increased thirst, muscle cramps, nausea, vomiting, uneven heartbeat
  • Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing, tiredness
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, or heart failure.
  • This medicine may cause the following problems:Low blood sugar or low potassium levels in the bloodFluid retention or heart failure (when used with a thiazolidinedione [TZD] medicine)
  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Never share insulin pens or needles with anyone. Sharing these can pass hepatitis virus, HIV, and other illnesses from one person to another.
What is Apidra (insulin glulisine) used for?
Apidra is FDA-approved to improve blood sugar control in adults with diabetes mellitus and in children 4 years of age and older with type 1 diabetes. Sanofi's patient labeling notes it is not known whether Apidra is safe or effective in children under 4 with type 1 diabetes or in children with type 2 diabetes. It is a rapid-acting mealtime insulin, so it covers the blood sugar rise from eating and is normally used with a longer-acting basal insulin, or in type 2 diabetes with oral diabetes medicines. It is injected under the skin using a vial and syringe, the SoloStar prefilled pen, or an insulin pump.
Is Apidra the same as Humalog or NovoLog?
No, but they are close cousins. All three are rapid-acting mealtime insulins used the same way. Apidra is insulin glulisine, Humalog is insulin lispro, and NovoLog is insulin aspart. They are different molecules from different manufacturers and are not automatically interchangeable at the pharmacy the way a generic is. Only your prescriber should switch you from one to another.
How long before a meal should you inject Apidra?
The FDA label says to inject Apidra within 15 minutes before a meal or within 20 minutes after you start eating. It generally begins working within about 15 minutes, and blood levels peak around an hour after injection. Follow the exact timing your doctor gives you, and do not inject it and then skip or delay the meal, since that raises the risk of low blood sugar.
Is there a generic version of Apidra?
No. There is no FDA-approved, substitutable generic or interchangeable version of insulin glulisine in the United States, so there is no generic Apidra to ask for. Other rapid-acting mealtime insulins exist, such as insulin lispro products (Humalog, Admelog) and insulin aspart (NovoLog), but a pharmacist cannot substitute them for Apidra without a new prescription from your doctor.
How much does Apidra cost without insurance?
The cash price depends on your dose, whether you use vials or SoloStar pens, how many you need, and which pharmacy you use, and prices can differ a lot between chains in the same town. Before using any discount coupon, check Sanofi's Insulins Valyou Savings Program on the manufacturer's Apidra website: it is open to uninsured patients and to insured patients who choose to pay cash outside their prescription plan, and it caps what you pay for a 30-day supply of Sanofi insulin. Sanofi Patient Connection is a separate patient assistance program for people who need more help, and there is also a co-pay savings card for people with commercial insurance. If you have Medicare Part D, your plan already caps your out-of-pocket cost for a month's supply of covered insulin, so paying cash is usually the wrong move. Otherwise, enter your ZIP code above to compare today's cash price near you with the free Rx.com coupon.
How much does Apidra cost without insurance?
The price of Apidra without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 26% off retail prices with a free Rx.com coupon.
What are the common side effects of Apidra?
Common side effects of Apidra may include: Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Dry mouth, increased thirst, muscle cramps, nausea, vomiting, uneven heartbeat, Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing, tiredness. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Apidra?
Generic versions may be available for Apidra. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Apidra on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Apidra?
The cheapest pharmacy for Apidra depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Apidra near you.

Apidra Coupons & Prices

Apidra 10ML of 100UNIT/ML

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Apidra 10ml of 100unit/ml (1)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for an Apidra coupon? Apidra (insulin glulisine) is a brand-name rapid-acting mealtime insulin from Sanofi, sold as vials and as the Apidra SoloStar prefilled pen. There is no FDA-approved generic or interchangeable version of insulin glulisine, so the brand is what you fill, and the cash price can vary a lot from one pharmacy to the next. Rx.com gives you a free cash-price coupon you can use at most major pharmacies whether or not you have insurance. Before you use any coupon, compare it against your insurance and against Sanofi's own insulin savings programs, which are described below. Enter your ZIP code above to see today's price for your dose and pen or vial count at pharmacies near you.

What is Apidra (insulin glulisine) and how does it work?

Apidra is a rapid-acting human insulin analog. It is FDA-approved to improve blood sugar control in adults with diabetes mellitus and in pediatric patients; the pediatric evidence in the label comes from a study in children 4 years of age and older with type 1 diabetes, and Sanofi's patient labeling states it is not known whether Apidra is safe or effective in children under 4 with type 1 diabetes or in children with type 2 diabetes. It is a mealtime insulin (sometimes called a bolus or prandial insulin), which means it covers the rise in blood sugar that comes from eating. It is normally used along with a longer-acting basal insulin, or in type 2 diabetes along with oral diabetes medicines.

Apidra works fast. It generally begins working within about 15 minutes, and the label describes a more rapid onset and shorter duration of action than regular human insulin, with blood levels peaking around an hour after injection. Because of that speed, the label directs you to inject it within 15 minutes before a meal or within 20 minutes after you start eating. It is given as an injection under the skin using a vial and syringe, the SoloStar prefilled pen, or a continuous infusion through an insulin pump. It can also be given into a vein, but only under direct medical supervision in a healthcare setting.

Apidra cost: manufacturer savings programs vs. the Rx.com cash coupon

The "Apidra coupon" search results are usually a mix of several different things, and it helps to know which one applies to you. Sanofi runs an official co-pay savings card for Apidra, described on the manufacturer's own Apidra website. Like most brand savings cards, it is generally limited to people with commercial (private) insurance, and people with Medicare, Medicaid, TRICARE, VA, or other government coverage are typically not eligible.

Just as important, and often missed: Sanofi also runs the Insulins Valyou Savings Program, which is aimed at people who are uninsured or who have a prescription plan but choose to pay cash outside of it. It covers Apidra and caps what you pay for a 30-day supply of Sanofi insulin. If you are paying cash, this is worth pricing out before you use any discount coupon, including ours. Sanofi Patient Connection is a separate patient assistance application for people who need help beyond those programs. Eligibility rules, the amount of help, and program terms are set by the manufacturer and change over time, so check the current terms on Sanofi's site rather than relying on a summary.

The Rx.com coupon is different from all of those. It is a cash-price discount, not insurance and not a manufacturer card. It can be an option if your plan does not cover Apidra, if a manufacturer card is declined at the register, or if you simply want to compare what different pharmacies charge. You cannot combine it with insurance on the same fill. If you have Medicare Part D, be careful before paying cash at all: Part D caps your out-of-pocket cost for a month's supply of each covered insulin at a fixed low amount, with no deductible applied to insulin, and a cash discount coupon is unlikely to beat that. Run your ZIP code above to see today's Apidra cash price near you, then compare it against your plan and against Sanofi's programs before you decide.

Is there a generic for Apidra? Alternatives and how they compare

There is no FDA-approved, substitutable generic or interchangeable biosimilar of insulin glulisine on the US market, so there is no generic swap for Apidra itself. What does exist are other rapid-acting mealtime insulins that are used the same way. Your prescriber decides which one fits you; a pharmacist cannot simply substitute one for another the way they can with a true generic.

  • Humalog (insulin lispro) and Admelog (a follow-on insulin lispro product) are rapid-acting mealtime insulins.
  • NovoLog (insulin aspart) is another rapid-acting mealtime insulin.
  • Lantus (insulin glargine) and Toujeo (insulin glargine, higher concentration) are long-acting basal insulins. They are not interchangeable with Apidra; they are the background insulin many people take alongside a mealtime insulin like Apidra.

If cost is the reason you are considering a switch, talk to your prescriber and pharmacist about which mealtime insulin your plan or your budget favors. Prices for insulin products vary by pharmacy, by plan, and by manufacturer program, so compare the actual out-of-pocket cost of each option rather than assuming one brand is cheaper. Never change insulin products, doses, or timing on your own.

Apidra safety: what to know before you inject

Apidra does not carry a boxed warning, but the FDA label flags several risks worth knowing. Low blood sugar (hypoglycemia) is the most common problem and can be severe or life-threatening; the risk goes up with changes in meals, exercise, dose, or other glucose-lowering drugs, especially sulfonylureas, and some people lose the warning symptoms over time. Medication mix-ups are a real danger: always read the label before you inject, because confusing a rapid-acting insulin with a long-acting one can cause serious high or low blood sugar. Never share an Apidra SoloStar pen or needles with anyone, even with a new needle, because of the risk of passing bloodborne infections.

Other label warnings include severe allergic reactions, including anaphylaxis (stop the drug and get help if this happens); low potassium (hypokalemia), which can be life-threatening and may need monitoring in people at risk; and fluid retention and heart failure when used with thiazolidinedione (TZD) diabetes drugs. If you use an external insulin pump, do not dilute Apidra or mix it with any other insulin in the pump, and change the infusion set and reservoir as directed, since a pump failure can lead to high blood sugar or diabetic ketoacidosis. Dose adjustments may be needed if you have kidney or liver problems. This page is general information, not medical advice. Talk with your doctor or pharmacist about your own dose, timing, and low-blood-sugar plan.

Sources & accuracy

This Apidra information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Apidra on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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