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Cevimeline Hcl Capsule — prescription drug image

Cevimeline Hcl

Cevimeline HCl 30MG

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What is Cevimeline Hcl?

Evoxac is used to treat a certain symptom (dry mouth) caused by Sjogren Syndrome. Cevimeline is the generic version of Evoxac. Evoxac cost around $806 for 90, 30 mg capsules. You can use our Rx.com savings offer to get an average Evoxac discount of up to 80% off of the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Cevimeline Hcl ?

Evoxac is used to treat a certain symptom (dry mouth) caused by Sjogren Syndrome. Cevimeline is the generic version of Evoxac. Evoxac cost around $806 for 90, 30 mg capsules. You can use our Rx.com savings offer to get an average Evoxac discount of up to 80% off of the retail price at participating pharmacies near you.
  • Severe nausea or vomiting, stomach pain, dark urine, yellow eyes or skin
  • Uncontrollable shaking
  • Uncontrollable shaking
  • Trouble breathing, chest tightness
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision or change in vision, confusion
  • Fainting, lightheadedness, dizziness
  • Fast, slow, or irregular heartbeat
  • Pain or burning feeling when you urinate, bloody or cloudy urine, pain in the lower back or side
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have heart or blood vessel disease, lung disease or breathing problems (including asthma, bronchitis, COPD), eye problems, or a history of chest pain, heart attack, kidney stones, or gallbladder stones.
  • This medicine may cause the following problems:Heart rhythm problemsBreathing problemsGallbladder problemsKidney problems
  • This medicine may cause blurred or decreased vision, especially at night. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Nausea or vomiting
  • Pain or burning when you urinate
  • Trouble breathing
  • Uncontrollable shaking
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is cevimeline HCl used for?
Cevimeline HCl is FDA-approved to treat the symptoms of dry mouth (xerostomia) in people with Sjogren's syndrome. It is a cholinergic agonist that stimulates the salivary glands to make more saliva.
How long does it take for cevimeline to work for dry mouth?
Cevimeline begins stimulating saliva production after each dose, and the usual regimen is 30 mg three times daily. Some people notice relief fairly soon, while for others it may take consistent use over days to weeks to feel the full benefit. Ask your provider what to expect for your situation.
What are the most common side effects of cevimeline?
The most common side effects are excessive sweating, nausea, runny nose (rhinitis), and diarrhea. Heavy sweating can cause dehydration, and the medicine may temporarily affect vision, including night vision. Contact your provider if side effects are bothersome or persistent.
Is cevimeline the same as pilocarpine?
No. Cevimeline and pilocarpine are two different medicines, though both are cholinergic agonists that work on the same muscarinic receptors to increase saliva for dry mouth. Your provider chooses between them based on your needs and how you respond.
Who should not take cevimeline?
Cevimeline should not be taken by people with uncontrolled asthma, a known allergy to cevimeline, acute iritis, or narrow-angle (angle-closure) glaucoma. It should be used with caution in people with heart disease or with controlled asthma, chronic bronchitis, or COPD. Review your full health history with your provider first.
How much does Cevimeline Hcl cost without insurance?
The price of Cevimeline Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 64% off retail prices with a free Rx.com coupon.
What are the common side effects of Cevimeline Hcl?
Common side effects of Cevimeline Hcl may include: Severe nausea or vomiting, stomach pain, dark urine, yellow eyes or skin, Uncontrollable shaking, Uncontrollable shaking, Trouble breathing, chest tightness, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Cevimeline Hcl?
Generic versions may be available for Cevimeline Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Cevimeline Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Cevimeline Hcl?
The cheapest pharmacy for Cevimeline Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Cevimeline Hcl near you.

Cevimeline Hcl Coupons & Prices

Cevimeline HCl 30MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Cevimeline Hcl Capsule — prescription drug image
Prescription
Cevimeline Hcl 30mg (30)
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Looking for a cevimeline HCl coupon? Cevimeline hydrochloride is the affordable generic form of Evoxac, a prescription medicine that treats dry mouth (xerostomia) in people with Sjogren's syndrome. Because it is available as a low-cost generic, cash prices are often modest, but they still vary widely from one pharmacy to the next, so it pays to compare before you fill. Enter your ZIP above to see today's price and print a free Rx.com discount coupon accepted at pharmacies nationwide.

What is cevimeline HCl and how does it work?

Cevimeline hydrochloride is a cholinergic agonist, meaning it works like the body's own signal to the salivary glands. It binds to muscarinic (M3) receptors on those glands and stimulates them to produce more saliva. This is why it is FDA-approved to relieve the symptoms of dry mouth in patients with Sjogren's syndrome, an autoimmune condition that reduces moisture in the mouth and eyes.

Cevimeline is the generic equivalent of the brand-name drug Evoxac. The usual dose is 30 mg taken by mouth three times daily, but always follow the exact directions your provider gives you.

Cevimeline HCl cost and how to save without insurance

Cevimeline is available as an FDA-approved generic, so it is generally one of the more budget-friendly options for treating dry mouth even if you pay cash. That said, the price you are quoted can differ a great deal depending on which pharmacy you use, so comparing is the single best way to avoid overpaying. Rx.com compares prices across more than 60,000 pharmacies so you can find the lowest cash price near you.

A free Rx.com coupon can be used whether or not you have insurance, and it is often worth checking the coupon price against your plan's copay. Enter your ZIP above to see today's price at pharmacies near you.

Alternatives and related medicines

Cevimeline is not the only medicine that stimulates saliva. The other prescription cholinergic agonist commonly used for dry mouth is pilocarpine, sold under the brand name Salagen. Both work on the same type of receptor, though they are different molecules and your provider will decide which is the better fit for you.

If you have been prescribed one of these instead of cevimeline, you can compare prices for each on Rx.com to see which offers the best cash price near you.

Safety, side effects, and who should not take it

Cevimeline has no boxed warning, but it is not right for everyone. It should not be used by people with uncontrolled asthma, a known allergy to cevimeline, acute iritis, or narrow-angle (angle-closure) glaucoma, because it can narrow the pupil. Use caution if you have heart disease, since it can affect heart rate or rhythm, and if you have controlled asthma, chronic bronchitis, or COPD, because it can increase airway secretions and resistance.

The most common side effects include excessive sweating, nausea, runny nose (rhinitis), and diarrhea. Heavy sweating can lead to dehydration, so drink enough fluids, and be aware the medicine may blur vision or reduce night vision, so take care driving at night. Cevimeline can interact with beta-blockers and with drugs that have anticholinergic effects. This is general information and not medical advice, so talk with your doctor or pharmacist about your full health history before starting cevimeline.

Sources & accuracy

This Cevimeline Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Cevimeline Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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