Impact-Site-Verification: 2721d812-1059-4270-b9fa-5c1654788cd1

Pilocarpine Hcl Tablet — prescription drug image

Pilocarpine Hcl

Pilocarpine HCl 5MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes

What is Pilocarpine Hcl?

Pilocarpine HCl is an eye drop medication commonly prescribed for treating glaucoma and dry mouth. By increasing fluid drainage from the eye and stimulating saliva production, it effectively manages eye pressure and oral dryness. Users can easily obtain prescriptions online at Rx.com, and explore savings options and coupons for reduced costs.

Prescription savings · · · ·

What is Pilocarpine Hcl ?

Pilocarpine HCl is an eye drop medication commonly prescribed for treating glaucoma and dry mouth. By increasing fluid drainage from the eye and stimulating saliva production, it effectively manages eye pressure and oral dryness. Users can easily obtain prescriptions online at Rx.com, and explore savings options and coupons for reduced costs.
  • Severe nausea, vomiting, or diarrhea
  • Sweating
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred or changes in vision, eye pain or irritation
  • Red, watery, or itchy eyes
  • Redness of the white part of the eyes or inside of the eyelids
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have asthma or other eye problems (including iritis, retinal problems).
  • This medicine may cause serious eye or vision problems, including retinal detachment, retinal tear.
  • This medicine may cause blurred vision and may make you have trouble seeing at night or in dim light. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
What is pilocarpine HCl used for?
Pilocarpine hydrochloride oral tablets are FDA-approved to treat the symptoms of dry mouth (xerostomia) in two situations: dry mouth caused by salivary gland hypofunction after radiation therapy for cancer of the head and neck, and dry mouth in people with Sjogren's syndrome. The tablets work by stimulating the salivary glands to produce more saliva. Pilocarpine eye drops are a separate dosage form approved for different conditions.
How long does it take for pilocarpine to work for dry mouth?
That varies from person to person, and the label does not promise a set timeline. Your doctor may start you at 5 mg three times a day for dry mouth after radiation, or 5 mg four times a day for Sjogren's syndrome, and adjust the dose based on how you respond and how well you tolerate it. Ask your prescriber how long to give it before deciding whether it is helping you, and do not increase the dose on your own.
What are the most common side effects of pilocarpine tablets?
Excessive sweating is the most common side effect, and it can lead to dehydration, so drink enough fluids and tell your doctor if it is heavy. Other common effects include nausea, runny nose, diarrhea, chills, flushing, more frequent urination, dizziness, and headache. Pilocarpine can also blur vision and affect depth perception, especially at night, which can make driving unsafe. Contact your doctor about side effects that bother you or do not go away.
Who should not take pilocarpine?
Pilocarpine tablets are contraindicated in people with uncontrolled asthma, anyone with a known hypersensitivity to pilocarpine, and anyone for whom pupil constriction would be harmful, such as with acute iritis or narrow-angle glaucoma. Caution and close medical supervision are advised for people with significant cardiovascular disease, COPD or chronic bronchitis, gallstones or biliary disease, kidney stones, or cognitive or psychiatric conditions, and for people taking beta-blockers or other cholinergic or anticholinergic medicines. A lower dose is advised in moderate liver impairment. Tell your doctor about all your conditions and medicines before starting.
Is pilocarpine the same as Salagen?
Salagen is the brand name for pilocarpine hydrochloride oral tablets, and generic pilocarpine hydrochloride tablets contain the same active ingredient. An FDA-approved generic is marketed in the US, so pharmacies can typically substitute it unless your prescriber requires the brand. Note that the name pilocarpine is also used for eye drops (brands such as Isopto Carpine, Vuity, and Qlosi), which are a different dosage form for different conditions and are approved separately.
How much does Pilocarpine Hcl cost without insurance?
The price of Pilocarpine Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 56% off retail prices with a free Rx.com coupon.
What are the common side effects of Pilocarpine Hcl?
Common side effects of Pilocarpine Hcl may include: Severe nausea, vomiting, or diarrhea, Sweating, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Blurred or changes in vision, eye pain or irritation, Red, watery, or itchy eyes. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Pilocarpine Hcl?
Generic versions may be available for Pilocarpine Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Pilocarpine Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Pilocarpine Hcl?
The cheapest pharmacy for Pilocarpine Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Pilocarpine Hcl near you.

Pilocarpine Hcl Coupons & Prices

Pilocarpine HCl 5MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Pilocarpine Hcl Tablet — prescription drug image
Prescription
Pilocarpine Hcl 5mg (30)
your area ·
QUAD by MEDVi · 4-in-1 ED treatment

4 ED medications in one dose

Sildenafil, tadalafil, PT-141 & L-Citrulline · Works in ~15 min · Lasts up to 36 hours

$114/mo Consult, meds & shipping included 4-in-1 formula
See QUAD by MEDVi Free online visit · No commitment
QUAD by MEDVi is a compounded prescription treatment; eligibility is determined by a licensed provider after an online visit. Pricing and product details are set by MEDVi and may change. Not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer.

A pilocarpine HCl coupon from Rx.com can be used at the pharmacy counter when you are paying cash for generic pilocarpine hydrochloride tablets, the prescription medicine approved to treat dry mouth (xerostomia) caused by radiation therapy for head and neck cancer or by Sjogren's syndrome. Pilocarpine tablets are available as an FDA-approved generic, and what you actually pay can differ quite a bit from one pharmacy to the next, even between stores on the same street. Rx.com compares cash prices across more than 60,000 pharmacies, so enter your ZIP code above to see today's price near you and bring the coupon with you.

What is pilocarpine HCl and how does it work?

Pilocarpine hydrochloride is a cholinergic agonist, also called a muscarinic agonist or parasympathomimetic. In plain terms, it stimulates the nerve signals that tell your glands to produce fluid. Because it increases saliva, it is classed as a sialagogue, which simply means a medicine that makes you produce more spit. The oral tablets come in 5 mg and 7.5 mg strengths and are sold generically as well as under the brand name Salagen.

The FDA-approved uses for the oral tablets are treating the symptoms of dry mouth from salivary gland hypofunction caused by radiotherapy for head and neck cancer, and treating dry mouth symptoms in people with Sjogren's syndrome. Typical dosing described in the label is 5 mg three times a day for dry mouth after radiation, titrated as needed up to a maximum of 30 mg per day, and 5 mg four times a day for Sjogren's syndrome. Pilocarpine eye drops used for glaucoma or presbyopia are a completely different dosage form with their own separate FDA approvals, and this page's coupon is for the oral tablets.

What pilocarpine tablets cost without insurance

There is no manufacturer copay or savings card for generic pilocarpine hydrochloride tablets. If you are paying cash, either because you have no insurance or because your plan does not cover this medicine well, the coupon price is what matters. Cash prices for the same tablet, same strength, and same quantity are not standardized in the US: pharmacies set their own, and the spread between the cheapest and most expensive nearby pharmacy can be meaningful. That is exactly why comparing before you fill is worth the two minutes.

Rx.com checks cash prices at over 60,000 US pharmacies, including major chains and independents, and shows you what each one charges today for your strength and quantity. Enter your ZIP code above to see the current price near you, then show the coupon to the pharmacist before they ring up the prescription. The coupon is a cash-price discount, not insurance, and it cannot be combined with your insurance benefit on the same fill, so it is worth asking the pharmacist which is cheaper for you.

Alternatives and related medicines

The brand-name version of oral pilocarpine tablets is Salagen. Because an FDA-approved generic is marketed and substitutable, most pharmacies will fill your prescription with generic pilocarpine hydrochloride unless your prescriber specifies otherwise. Prices for the brand and the generic are set separately by each pharmacy, so it is worth checking both rather than assuming.

The other prescription medicine in this space is cevimeline, sold as Evoxac and also available generically as cevimeline. It is a different cholinergic agonist used for dry mouth in Sjogren's syndrome. If you are looking at eye drops rather than tablets, see pilocarpine for the ophthalmic dosage form, which treats different conditions entirely. Which medicine is right for you is a decision for you and your prescriber, not something a price comparison can answer.

Safety information you should know

Pilocarpine tablets do not carry a boxed warning. They should not be used by people with uncontrolled asthma, by anyone with a known hypersensitivity to pilocarpine, or when pupil constriction (miosis) would be harmful, such as in acute iritis or narrow-angle glaucoma. Because pilocarpine increases airway resistance, bronchial muscle tone, and bronchial secretions, it calls for caution in asthma, COPD, and chronic bronchitis. It should be used with caution and close medical supervision in people with significant cardiovascular disease, since it may cause changes in blood pressure and heart rate and has been associated with pulmonary edema.

Excessive sweating is the most common side effect and can lead to dehydration, so drink enough fluids and tell your doctor if sweating is heavy. Other common effects include nausea, runny nose, diarrhea, chills, flushing, needing to urinate more often, dizziness, and headache. Pilocarpine can blur your vision and impair depth perception, especially at night, which can make driving unsafe. Caution is also advised with gallstones or biliary tract disease, kidney stones, cognitive or psychiatric conditions, and if you take beta-blockers (a risk of heart conduction problems) or other medicines with cholinergic or anticholinergic activity. A lower dose is advised in moderate liver impairment. This is a summary, not medical advice, and not a complete list of risks. Talk with your doctor or pharmacist about your own health history and medicines.

Sources & accuracy

This Pilocarpine Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Pilocarpine Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

Sponsored
Sesame Care — 350+ medications for $1 without insurance
¿Buscando esta página en español?

Browse more medications: starting with P · full A-Z directory · by condition · common drugs

Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


Don't Miss Out On Savings!

Rx.com does not warrant the accuracy of the information on this website. All information on this site is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of a drug is safe, appropriate, or effective for you. Consult your healthcare professional before using any drug. All logos, brand names and trademarks on this website are the property of their respective owners. Rx.com is not endorsed or affiliated with any brands represented on this website."

Pharmacy discounts are Not Insurance, and are Not Intended as a Substitute for Insurance THE DISCOUNT IS ONLY AVAILABLE AT PARTICIPATING PHARMACIES As an Amazon Associate, we earn from qualifying purchases.

2026 All Rights Reserved | Rx.com®