Chlorpromazine Hcl
chlorproMAZINE HCl 25MG
What is Chlorpromazine Hcl?
Chlorpromazine HCl, commonly known as Thorazine, is a phenothiazine antipsychotic used primarily to treat psychotic disorders such as schizophrenia and manic-depression, as well as to control nausea and vomiting, anxiety, and severe behavioral problems in children. It functions by adjusting the balance of certain neurotransmitters in the brain, notably dopamine, which helps to improve mood, thought, and behavior. Chlorpromazine is administered orally, intramuscularly, or intravenously and is known for its sedative effects and potential side effects including drowsiness, dizziness, and extrapyramidal symptoms.Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Drowsiness or dizziness, confusion
- Fast or uneven heartbeat
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have asthma, emphysema, breast cancer, trouble urinating, glaucoma, seizures, or a bone marrow or blood disorder. Tell your doctor if you have heart, kidney, or liver disease, or lupus.
- This medicine may cause drowsiness or affect your sight. Do not drive or do anything that could be dangerous until you know how this medicine affects you.
- This medicine may cause the following problems: Neuroleptic malignant syndrome (NMS)Tardive dyskinesia
- This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
Prescription savings · · · ·
What is Chlorpromazine Hcl ?
Chlorpromazine HCl, commonly known as Thorazine, is a phenothiazine antipsychotic used primarily to treat psychotic disorders such as schizophrenia and manic-depression, as well as to control nausea and vomiting, anxiety, and severe behavioral problems in children. It functions by adjusting the balance of certain neurotransmitters in the brain, notably dopamine, which helps to improve mood, thought, and behavior. Chlorpromazine is administered orally, intramuscularly, or intravenously and is known for its sedative effects and potential side effects including drowsiness, dizziness, and extrapyramidal symptoms.- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Drowsiness or dizziness, confusion
- Fast or uneven heartbeat
- Jerky muscle movement you cannot control (often in your face, tongue, or jaw)
- Seizures
- Tell your doctor if you are pregnant or breastfeeding, or if you have asthma, emphysema, breast cancer, trouble urinating, glaucoma, seizures, or a bone marrow or blood disorder. Tell your doctor if you have heart, kidney, or liver disease, or lupus.
- This medicine may cause drowsiness or affect your sight. Do not drive or do anything that could be dangerous until you know how this medicine affects you.
- This medicine may cause the following problems: Neuroleptic malignant syndrome (NMS)Tardive dyskinesia
- This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
Chlorpromazine Hcl Coupons & Prices
chlorproMAZINE HCl 25MG
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Chlorpromazine hydrochloride is the generic version of the older antipsychotic once sold under the brand name Thorazine, which is no longer marketed in the United States — today it's available only as a generic. Because pharmacy cash prices for the same generic drug can vary widely from one location to the next, it pays to compare before you fill a chlorpromazine hcl coupon. Rx.com compares pricing across more than 60,000 U.S. pharmacies, so enter your ZIP above to see today's price near you.
What Is Chlorpromazine Hydrochloride?
Chlorpromazine hydrochloride is a first-generation (typical) antipsychotic in the phenothiazine class. It's FDA-approved for schizophrenia and other psychotic disorders, the manic phase of bipolar disorder, severe behavioral problems in children ages 1 to 12 (combative, explosive hyperexcitability, or short-term treatment of hyperactive children showing excessive motor activity), nausea and vomiting, intractable hiccups, presurgical relief of restlessness and apprehension, acute intermittent porphyria, and as an adjunct treatment for tetanus. It's also sometimes used off-label for migraine and other headache pain in emergency-department settings, though that isn't an FDA-approved use.
The original brand, Thorazine, was discontinued in the U.S. market, so chlorpromazine is now available only as a generic medication.
Chlorpromazine HCL Cost and Coupons
Because chlorpromazine is generic-only, there's no brand-name version to compare it against, and there is currently no manufacturer savings card for this medication. That doesn't mean pricing is the same everywhere — cash prices for the same generic drug can still vary significantly from pharmacy to pharmacy depending on location, pharmacy type, and dosage strength.
That's why it's worth comparing before you fill your prescription. Enter your ZIP code above to see today's price at pharmacies near you and find where your chlorpromazine hcl prescription costs less.
Chlorpromazine Alternatives and Comparisons
Chlorpromazine belongs to an older group of antipsychotics often called first-generation or typical antipsychotics. If you and your provider are discussing options, other antipsychotics that sometimes come up include first-generation haloperidol, or newer second-generation (atypical) medications such as olanzapine, risperidone, and quetiapine.
For nausea and vomiting specifically, promethazine is another medication sometimes used, although it is not an antipsychotic. Only your prescriber can determine which medication and dose fit your diagnosis.
Chlorpromazine Safety Information
Chlorpromazine carries an FDA boxed warning: in elderly patients with dementia-related psychosis, antipsychotic drugs like chlorpromazine are associated with an increased risk of death, and chlorpromazine is not approved for treating dementia-related psychosis.
- Neuroleptic malignant syndrome (NMS), a rare but life-threatening reaction
- Tardive dyskinesia — involuntary movements that can become permanent with prolonged use
- QT prolongation and other heart-rhythm changes
- Orthostatic hypotension (a drop in blood pressure on standing)
- Agranulocytosis and other blood cell disorders
- Liver problems, including jaundice
- Lowered seizure threshold
- Severe sun sensitivity and significant drowsiness
Chlorpromazine should not be used by anyone with severe CNS depression or in a comatose state, or in children under 6 months old, and it should not be stopped abruptly without a doctor's guidance. This is not a complete list of risks — talk with your doctor or pharmacist about whether chlorpromazine is right and safe for you.
This Chlorpromazine Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Chlorpromazine Hcl on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.