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Chlorpromazine Hcl

chlorproMAZINE HCl 25MG

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What is Chlorpromazine Hcl?

Chlorpromazine HCl, commonly known as Thorazine, is a phenothiazine antipsychotic used primarily to treat psychotic disorders such as schizophrenia and manic-depression, as well as to control nausea and vomiting, anxiety, and severe behavioral problems in children. It functions by adjusting the balance of certain neurotransmitters in the brain, notably dopamine, which helps to improve mood, thought, and behavior. Chlorpromazine is administered orally, intramuscularly, or intravenously and is known for its sedative effects and potential side effects including drowsiness, dizziness, and extrapyramidal symptoms.

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What is Chlorpromazine Hcl ?

Chlorpromazine HCl, commonly known as Thorazine, is a phenothiazine antipsychotic used primarily to treat psychotic disorders such as schizophrenia and manic-depression, as well as to control nausea and vomiting, anxiety, and severe behavioral problems in children. It functions by adjusting the balance of certain neurotransmitters in the brain, notably dopamine, which helps to improve mood, thought, and behavior. Chlorpromazine is administered orally, intramuscularly, or intravenously and is known for its sedative effects and potential side effects including drowsiness, dizziness, and extrapyramidal symptoms.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Drowsiness or dizziness, confusion
  • Fast or uneven heartbeat
  • Jerky muscle movement you cannot control (often in your face, tongue, or jaw)
  • Seizures
  • Tell your doctor if you are pregnant or breastfeeding, or if you have asthma, emphysema, breast cancer, trouble urinating, glaucoma, seizures, or a bone marrow or blood disorder. Tell your doctor if you have heart, kidney, or liver disease, or lupus.
  • This medicine may cause drowsiness or affect your sight. Do not drive or do anything that could be dangerous until you know how this medicine affects you.
  • This medicine may cause the following problems: Neuroleptic malignant syndrome (NMS)Tardive dyskinesia
  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
What is chlorpromazine hydrochloride used for?
Chlorpromazine hydrochloride is FDA-approved to treat schizophrenia and other psychotic disorders, the manic phase of bipolar disorder, severe behavioral problems in children ages 1 to 12, nausea and vomiting, intractable hiccups, presurgical restlessness and apprehension, acute intermittent porphyria, and as an adjunct treatment for tetanus.
Is chlorpromazine the same as Thorazine?
Thorazine was the original brand name for chlorpromazine hydrochloride, but that brand has been discontinued in the U.S. Today, chlorpromazine is available only as a generic medication.
What are the side effects of chlorpromazine?
Chlorpromazine can cause significant sedation, orthostatic hypotension, anticholinergic effects, and severe sun sensitivity. More serious risks include neuroleptic malignant syndrome, tardive dyskinesia, QT prolongation and other heart-rhythm changes, blood cell disorders, liver problems, and a lowered seizure threshold. It also carries a boxed warning about increased risk of death in elderly patients with dementia-related psychosis. Talk with your doctor or pharmacist about the full list of risks.
Is chlorpromazine a controlled substance?
No. Chlorpromazine hydrochloride is not classified as a controlled substance.
How much does chlorpromazine cost without insurance?
Cash prices for chlorpromazine vary by pharmacy, location, and dosage strength, since it's available only as a generic with no brand or manufacturer savings card. Enter your ZIP code above to compare today's pricing at pharmacies near you.
How much does Chlorpromazine Hcl cost without insurance?
The price of Chlorpromazine Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Chlorpromazine Hcl?
Common side effects of Chlorpromazine Hcl may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Drowsiness or dizziness, confusion, Fast or uneven heartbeat, Jerky muscle movement you cannot control (often in your face, tongue, or jaw), Seizures. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Chlorpromazine Hcl?
Generic versions may be available for Chlorpromazine Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Chlorpromazine Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Chlorpromazine Hcl?
The cheapest pharmacy for Chlorpromazine Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Chlorpromazine Hcl near you.

Chlorpromazine Hcl Coupons & Prices

chlorproMAZINE HCl 25MG

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Chlorpromazine Hcl Tablet — prescription drug image
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Chlorpromazine hydrochloride is the generic version of the older antipsychotic once sold under the brand name Thorazine, which is no longer marketed in the United States — today it's available only as a generic. Because pharmacy cash prices for the same generic drug can vary widely from one location to the next, it pays to compare before you fill a chlorpromazine hcl coupon. Rx.com compares pricing across more than 60,000 U.S. pharmacies, so enter your ZIP above to see today's price near you.

What Is Chlorpromazine Hydrochloride?

Chlorpromazine hydrochloride is a first-generation (typical) antipsychotic in the phenothiazine class. It's FDA-approved for schizophrenia and other psychotic disorders, the manic phase of bipolar disorder, severe behavioral problems in children ages 1 to 12 (combative, explosive hyperexcitability, or short-term treatment of hyperactive children showing excessive motor activity), nausea and vomiting, intractable hiccups, presurgical relief of restlessness and apprehension, acute intermittent porphyria, and as an adjunct treatment for tetanus. It's also sometimes used off-label for migraine and other headache pain in emergency-department settings, though that isn't an FDA-approved use.

The original brand, Thorazine, was discontinued in the U.S. market, so chlorpromazine is now available only as a generic medication.

Chlorpromazine HCL Cost and Coupons

Because chlorpromazine is generic-only, there's no brand-name version to compare it against, and there is currently no manufacturer savings card for this medication. That doesn't mean pricing is the same everywhere — cash prices for the same generic drug can still vary significantly from pharmacy to pharmacy depending on location, pharmacy type, and dosage strength.

That's why it's worth comparing before you fill your prescription. Enter your ZIP code above to see today's price at pharmacies near you and find where your chlorpromazine hcl prescription costs less.

Chlorpromazine Alternatives and Comparisons

Chlorpromazine belongs to an older group of antipsychotics often called first-generation or typical antipsychotics. If you and your provider are discussing options, other antipsychotics that sometimes come up include first-generation haloperidol, or newer second-generation (atypical) medications such as olanzapine, risperidone, and quetiapine.

For nausea and vomiting specifically, promethazine is another medication sometimes used, although it is not an antipsychotic. Only your prescriber can determine which medication and dose fit your diagnosis.

Chlorpromazine Safety Information

Chlorpromazine carries an FDA boxed warning: in elderly patients with dementia-related psychosis, antipsychotic drugs like chlorpromazine are associated with an increased risk of death, and chlorpromazine is not approved for treating dementia-related psychosis.

  • Neuroleptic malignant syndrome (NMS), a rare but life-threatening reaction
  • Tardive dyskinesia — involuntary movements that can become permanent with prolonged use
  • QT prolongation and other heart-rhythm changes
  • Orthostatic hypotension (a drop in blood pressure on standing)
  • Agranulocytosis and other blood cell disorders
  • Liver problems, including jaundice
  • Lowered seizure threshold
  • Severe sun sensitivity and significant drowsiness

Chlorpromazine should not be used by anyone with severe CNS depression or in a comatose state, or in children under 6 months old, and it should not be stopped abruptly without a doctor's guidance. This is not a complete list of risks — talk with your doctor or pharmacist about whether chlorpromazine is right and safe for you.

Sources & accuracy

This Chlorpromazine Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Chlorpromazine Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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