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Clindamycin Phos-Benzoyl Perox

Clindamycin Phos-Benzoyl Perox 50GM of 1-5%

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What is Clindamycin Phos-Benzoyl Perox?

Clindamycin Phosphate-Benzoyl Peroxide is a topical medication used for the treatment of acne. Clindamycin is an antibiotic that reduces bacterial growth, while benzoyl peroxide has antimicrobial properties and helps to peel the skin. Together, they target both the bacterial and inflammatory components of acne, leading to clearer skin.

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What is Clindamycin Phos-Benzoyl Perox ?

Clindamycin Phosphate-Benzoyl Peroxide is a topical medication used for the treatment of acne. Clindamycin is an antibiotic that reduces bacterial growth, while benzoyl peroxide has antimicrobial properties and helps to peel the skin. Together, they target both the bacterial and inflammatory components of acne, leading to clearer skin.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Severe diarrhea or diarrhea that contains blood, stomach pain or cramps
  • Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding.
  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
What is clindamycin phosphate/benzoyl peroxide gel used for?
It is an FDA-approved topical gel for treating acne vulgaris, generally in people 12 years and older. Clindamycin suppresses acne-causing bacteria while benzoyl peroxide kills bacteria, helps keep pores clear, and limits antibiotic resistance. You apply a thin layer once or twice daily depending on the product. It is for use on the skin only, not by mouth.
How long does it take for clindamycin-benzoyl peroxide to clear acne?
Topical acne treatments generally take time, and improvement is usually gradual over several weeks of consistent daily use rather than overnight. Keep using it as prescribed even if you do not see fast results, and check in with your prescriber about how your skin is responding and whether to adjust treatment.
Can clindamycin/benzoyl peroxide bleach your skin, hair, or towels?
The benzoyl peroxide in this gel can bleach hair and colored fabric, so it may lighten towels, pillowcases, and clothing that it touches. Use care around dyed fabrics, consider white towels and bedding, and let the gel dry before it contacts fabric. It can also cause dryness, peeling, and redness of the skin.
What are the most common side effects of clindamycin-benzoyl peroxide gel?
The most common effects come from the benzoyl peroxide and include skin dryness, peeling, redness, burning, and stinging, especially when you first start. It can also increase sun sensitivity. Rarely, clindamycin has been linked to severe diarrhea or colitis, so stop and call your provider if you get significant or prolonged diarrhea. Serious allergic reactions are rare but possible.
Is clindamycin/benzoyl peroxide available as a generic and how much does it cost?
Yes, this combination gel is available as an FDA-approved generic, which is typically much cheaper than the brand versions like BenzaClin, Duac, Acanya, Onexton, and Neuac. Cash prices still vary widely by pharmacy, so comparing matters. Enter your ZIP above to see today's price at pharmacies near you and get a free Rx.com discount coupon accepted at more than 60,000 pharmacies.
How much does Clindamycin Phos-Benzoyl Perox cost without insurance?
The price of Clindamycin Phos-Benzoyl Perox without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 68% off retail prices with a free Rx.com coupon.
What are the common side effects of Clindamycin Phos-Benzoyl Perox?
Common side effects of Clindamycin Phos-Benzoyl Perox may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Severe diarrhea or diarrhea that contains blood, stomach pain or cramps. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Clindamycin Phos-Benzoyl Perox?
Generic versions may be available for Clindamycin Phos-Benzoyl Perox. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Clindamycin Phos-Benzoyl Perox on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Clindamycin Phos-Benzoyl Perox?
The cheapest pharmacy for Clindamycin Phos-Benzoyl Perox depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Clindamycin Phos-Benzoyl Perox near you.

Clindamycin Phos-Benzoyl Perox Coupons & Prices

Clindamycin Phos-Benzoyl Perox 50GM of 1-5%

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Clindamycin Phos-Benzoyl Perox Jar — prescription drug image
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a clindamycin-phos-benzoyl-perox coupon? This topical acne gel combines the antibiotic clindamycin phosphate with benzoyl peroxide, and it is available as a lower-cost FDA-approved generic (the brands include BenzaClin, Duac, Acanya, Onexton, and Neuac). Even so, the cash price can swing widely from one pharmacy to the next, which is exactly why comparing pays off. Enter your ZIP above to see today's price and a free Rx.com discount coupon accepted at more than 60,000 pharmacies nationwide.

What is clindamycin phosphate / benzoyl peroxide and how does it work?

Clindamycin phosphate / benzoyl peroxide is a topical combination gel that is FDA-approved to treat acne vulgaris, generally in people 12 years and older. It pairs two ingredients that work in different ways: clindamycin, a lincosamide antibiotic that suppresses the acne-causing bacteria Cutibacterium acnes, and benzoyl peroxide, an antibacterial and keratolytic that kills bacteria, helps keep pores clear, and limits the antibiotic resistance that clindamycin alone can encourage.

It comes in several fixed strengths, such as 1%/5%, 1.2%/2.5%, and 1.2%/3.75%. Depending on the specific product, you apply a thin layer to the affected skin once or twice daily. It is for use on the skin only. Follow your prescriber's and the label's directions, and talk with your provider about which strength and schedule fit you.

Cost of clindamycin / benzoyl peroxide without insurance

Because an FDA-approved, substitutable generic of this combination gel is on the market, it is typically far less expensive than the brand versions. But "generic" does not mean every pharmacy charges the same. Cash prices for topical acne gels vary a lot by pharmacy and location, so the store around the corner and the one across town may quote very different amounts for the same tube.

That is where comparing helps. Rx.com checks prices across more than 60,000 pharmacies so you can find a lower cash price near you, and you can bring a free Rx.com discount coupon even if you have no insurance or if your plan does not cover it. Enter your ZIP above to see today's price at pharmacies near you.

Related and alternative acne treatments

If you are comparing options, several related prescription acne treatments are commonly used. Your prescriber chooses based on your skin and acne type:

The brand-name equivalents of this exact combination include BenzaClin, Duac, Acanya, Onexton, and Neuac; the generic contains the same active ingredients. This is general information, not medical advice - your provider can help you choose.

Safety and side effects

This gel is for skin use only. Do not take it by mouth, and keep it away from your eyes, mouth, and other mucous membranes. Benzoyl peroxide commonly causes dryness, peeling, redness, burning, and stinging, especially early in treatment, and it can bleach hair and colored fabric such as towels and clothing. It may also make your skin more sensitive to sunlight, so minimize sun exposure and protect your skin. Rare but serious allergic (hypersensitivity) reactions, including anaphylaxis, have been reported with benzoyl peroxide products.

Clindamycin, even applied to the skin, has been associated with severe colitis, including Clostridioides difficile-associated diarrhea and pseudomembranous colitis; stop the medication and contact your provider if you develop significant or prolonged diarrhea. Avoid using it together with erythromycin. This is a brief summary, not a full list - read the label and talk with your doctor or pharmacist about your health history and other medications.

Sources & accuracy

This Clindamycin Phos-Benzoyl Perox information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Clindamycin Phos-Benzoyl Perox on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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