Clindamycin Phos-Benzoyl Perox
Clindamycin Phos-Benzoyl Perox 50GM of 1-5%
What is Clindamycin Phos-Benzoyl Perox?
Clindamycin Phosphate-Benzoyl Peroxide is a topical medication used for the treatment of acne. Clindamycin is an antibiotic that reduces bacterial growth, while benzoyl peroxide has antimicrobial properties and helps to peel the skin. Together, they target both the bacterial and inflammatory components of acne, leading to clearer skin.Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Severe diarrhea or diarrhea that contains blood, stomach pain or cramps
Warnings
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Tell your doctor if you are pregnant or breastfeeding.
- This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
- This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
Prescription savings · · · ·
What is Clindamycin Phos-Benzoyl Perox ?
Clindamycin Phosphate-Benzoyl Peroxide is a topical medication used for the treatment of acne. Clindamycin is an antibiotic that reduces bacterial growth, while benzoyl peroxide has antimicrobial properties and helps to peel the skin. Together, they target both the bacterial and inflammatory components of acne, leading to clearer skin.- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Severe diarrhea or diarrhea that contains blood, stomach pain or cramps
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Tell your doctor if you are pregnant or breastfeeding.
- This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
- This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
Clindamycin Phos-Benzoyl Perox Coupons & Prices
Clindamycin Phos-Benzoyl Perox 50GM of 1-5%
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Looking for a clindamycin-phos-benzoyl-perox coupon? This topical acne gel combines the antibiotic clindamycin phosphate with benzoyl peroxide, and it is available as a lower-cost FDA-approved generic (the brands include BenzaClin, Duac, Acanya, Onexton, and Neuac). Even so, the cash price can swing widely from one pharmacy to the next, which is exactly why comparing pays off. Enter your ZIP above to see today's price and a free Rx.com discount coupon accepted at more than 60,000 pharmacies nationwide.
What is clindamycin phosphate / benzoyl peroxide and how does it work?
Clindamycin phosphate / benzoyl peroxide is a topical combination gel that is FDA-approved to treat acne vulgaris, generally in people 12 years and older. It pairs two ingredients that work in different ways: clindamycin, a lincosamide antibiotic that suppresses the acne-causing bacteria Cutibacterium acnes, and benzoyl peroxide, an antibacterial and keratolytic that kills bacteria, helps keep pores clear, and limits the antibiotic resistance that clindamycin alone can encourage.
It comes in several fixed strengths, such as 1%/5%, 1.2%/2.5%, and 1.2%/3.75%. Depending on the specific product, you apply a thin layer to the affected skin once or twice daily. It is for use on the skin only. Follow your prescriber's and the label's directions, and talk with your provider about which strength and schedule fit you.
Cost of clindamycin / benzoyl peroxide without insurance
Because an FDA-approved, substitutable generic of this combination gel is on the market, it is typically far less expensive than the brand versions. But "generic" does not mean every pharmacy charges the same. Cash prices for topical acne gels vary a lot by pharmacy and location, so the store around the corner and the one across town may quote very different amounts for the same tube.
That is where comparing helps. Rx.com checks prices across more than 60,000 pharmacies so you can find a lower cash price near you, and you can bring a free Rx.com discount coupon even if you have no insurance or if your plan does not cover it. Enter your ZIP above to see today's price at pharmacies near you.
Related and alternative acne treatments
If you are comparing options, several related prescription acne treatments are commonly used. Your prescriber chooses based on your skin and acne type:
- clindamycin and clindamycin phosphate - the topical antibiotic used on its own
- benzoyl peroxide - the antibacterial ingredient by itself
- adapalene / benzoyl peroxide - a retinoid-plus-benzoyl-peroxide combination
- tretinoin - a topical retinoid
- doxycycline - an oral antibiotic option for some cases
The brand-name equivalents of this exact combination include BenzaClin, Duac, Acanya, Onexton, and Neuac; the generic contains the same active ingredients. This is general information, not medical advice - your provider can help you choose.
Safety and side effects
This gel is for skin use only. Do not take it by mouth, and keep it away from your eyes, mouth, and other mucous membranes. Benzoyl peroxide commonly causes dryness, peeling, redness, burning, and stinging, especially early in treatment, and it can bleach hair and colored fabric such as towels and clothing. It may also make your skin more sensitive to sunlight, so minimize sun exposure and protect your skin. Rare but serious allergic (hypersensitivity) reactions, including anaphylaxis, have been reported with benzoyl peroxide products.
Clindamycin, even applied to the skin, has been associated with severe colitis, including Clostridioides difficile-associated diarrhea and pseudomembranous colitis; stop the medication and contact your provider if you develop significant or prolonged diarrhea. Avoid using it together with erythromycin. This is a brief summary, not a full list - read the label and talk with your doctor or pharmacist about your health history and other medications.
This Clindamycin Phos-Benzoyl Perox information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Clindamycin Phos-Benzoyl Perox on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.