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Dexilant

Dexilant 60MG

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What is Dexilant?

Dexilant (dexlansoprazole) is a prescription medication used to treat gastroesophageal reflux disease (GERD), heal erosive esophagitis, and reduce frequent heartburn. As a proton pump inhibitor (PPI), it lowers stomach acid production to help relieve symptoms and promote healing of the esophagus.

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What is Dexilant ?

Dexilant (dexlansoprazole) is a prescription medication used to treat gastroesophageal reflux disease (GERD), heal erosive esophagitis, and reduce frequent heartburn. As a proton pump inhibitor (PPI), it lowers stomach acid production to help relieve symptoms and promote healing of the esophagus.

  • Unusual bleeding, bruising, tiredness, or weakness
  • Joint pain, rash on your cheeks or arms that gets worse in the sun
  • Fever, chills, cough, stuffy or runny nose, sore throat, body aches
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Seizures, dizziness, fast or uneven heartbeat, muscle cramps or twitching
  • Dry mouth, increased thirst, confusion, numbness and tingling around the mouth, fingertips, or feet
  • Severe diarrhea that does not go away, stomach cramps or pain, nausea, vomiting, loss of appetite, weight loss
  • Blistering, peeling, red skin rash
  • Swelling in your body, unusual weight gain, changes in how much or how often you urinate
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lupus, or osteoporosis.
  • This medicine may cause the following problems:Kidney problems, including acute tubulointerstitial nephritisIncreased risk of broken bones in the hip, wrist, or spine (more likely if used several times per day or longer than 1 year)Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS)LupusFundic gland polyps (abnormal growth in the upper part of your stomach)
  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
What is Dexilant used for?
Dexilant (dexlansoprazole) is FDA-approved to heal all grades of erosive esophagitis, to maintain that healing and relieve the associated heartburn, and to treat heartburn caused by symptomatic non-erosive GERD. It is a proton pump inhibitor that lowers stomach acid.
Is there a generic version of Dexilant available?
Yes. Dexilant is available as a generic called dexlansoprazole. Choosing the generic is often the biggest way to lower your cost, so ask your pharmacist whether it is right for you and enter your ZIP above to compare today's prices.
What is the difference between Dexilant and Nexium or Prilosec?
All three are proton pump inhibitors that reduce stomach acid, but they use different active ingredients: Dexilant is dexlansoprazole, Nexium is esomeprazole, and Prilosec is omeprazole. Dexilant's capsule releases the medicine in two pulses, which is designed to extend acid suppression. Which one is best depends on your condition, response, interactions, and cost, and is a decision for you and your prescriber.
What are the long-term side effects of taking Dexilant?
Long-term or high-dose PPI use has been associated with a higher risk of bone fractures, C. difficile diarrhea, low magnesium, vitamin B12 deficiency, acute interstitial nephritis (a kidney problem), lupus-related reactions, and benign stomach polyps. The usual guidance is to use the lowest effective dose for the shortest time needed. Talk with your doctor about long-term use.
Can I take Dexilant every day for GERD?
Dexilant is often taken once daily for the conditions it is approved for, but how long you should take it depends on your diagnosis and your doctor's guidance. Because of risks tied to long-term PPI use, providers generally aim for the lowest effective dose for the shortest necessary duration. Follow your prescriber's instructions and check in before continuing it indefinitely.
How much does Dexilant 60MG cost without insurance?
The price of Dexilant 60MG without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Dexilant 60MG?
Common side effects of Dexilant 60MG may include: Unusual bleeding, bruising, tiredness, or weakness, Joint pain, rash on your cheeks or arms that gets worse in the sun, Fever, chills, cough, stuffy or runny nose, sore throat, body aches, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Seizures, dizziness, fast or uneven heartbeat, muscle cramps or twitching. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Dexilant 60MG?
Generic versions may be available for Dexilant 60MG. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Dexilant 60MG on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Dexilant 60MG?
The cheapest pharmacy for Dexilant 60MG depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Dexilant 60MG near you.

Dexilant Coupons & Prices

Dexilant 60MG

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Dexilant Capsule Delayed Release — prescription drug image
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Dexilant 60mg (5)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a Dexilant coupon? Rx.com offers a free cash-price coupon you can use at the pharmacy counter to help lower the cost of Dexilant (dexlansoprazole), a prescription proton pump inhibitor (PPI) used to treat erosive esophagitis and heartburn from GERD. Enter your ZIP above to see today's price at pharmacies near you. Because dexlansoprazole is now available as a lower-cost generic, asking your pharmacist about the generic is often the biggest way to save.

What is Dexilant and how does it work?

Dexilant (dexlansoprazole, formerly sold as Kapidex) is a proton pump inhibitor, a class of medicines that reduces the amount of acid your stomach makes. It is FDA-approved to heal all grades of erosive esophagitis (damage to the esophagus caused by stomach acid), to maintain that healing and relieve the associated heartburn, and to treat heartburn linked to symptomatic non-erosive gastroesophageal reflux disease (GERD).

What sets Dexilant apart from most other PPIs is its dual delayed-release capsule. The capsule releases the medicine in two separate pulses, which is designed to extend how long stomach acid stays suppressed through the day. It is sometimes used off-label for other acid-related problems such as dyspepsia or when other PPIs have not worked well enough, but those uses should be guided by your doctor.

Dexilant cost: manufacturer savings card vs. Rx.com cash coupon

The manufacturer of Dexilant offers an official copay savings program through Takeda Patient Support, described on the brand's official website. Programs like this are generally limited to people with commercial (private) insurance, and the terms, eligibility, and any limits vary and can change, so read the details carefully. People with Medicare, Medicaid, or other government coverage typically do not qualify, and the card does nothing if you are paying cash.

That is where the Rx.com cash coupon fits. It is a discount on the cash price, so it can be used if you are uninsured, if you have Medicare or Medicaid, or if a manufacturer card is declined at the pharmacy. You cannot combine it with insurance, so you would use whichever brings your price lower. The single biggest lever, though, is that a generic version of dexlansoprazole now exists. Ask your pharmacist whether the generic is right for you and enter your ZIP above to compare today's prices near you. Takeda also runs a patient assistance program for eligible patients who cannot afford their medication; you can ask about it through the manufacturer's support resources.

Dexilant vs. Nexium, Prilosec, and other PPI alternatives

Dexilant belongs to the same proton pump inhibitor family as several widely used medicines, so they all work in a similar way but differ in their exact ingredient, dosing, and cost. If you and your doctor are weighing options, these related PPIs are commonly compared:

Which PPI is best depends on your diagnosis, how you respond, drug interactions, and price. Dexilant's twice-releasing capsule may help some people who need longer acid control, while others do just as well on a lower-cost generic. This is a decision for you and your prescriber, not a swap to make on your own.

Safety and long-term use

Dexilant has no boxed warning, and short courses are generally well tolerated. However, long-term or high-dose PPI use has been linked to a higher risk of bone fractures of the hip, wrist, and spine, Clostridioides difficile-associated diarrhea, low magnesium levels, vitamin B12 deficiency, a kidney inflammation called acute interstitial nephritis, and both skin and body-wide forms of lupus. Long-term use may also cause benign stomach growths called fundic gland polyps. Because of this, the general guidance is to use the lowest effective dose for the shortest time needed.

Tell your provider about all your medicines. Dexilant should not be taken with rilpivirine, it can reduce how well drugs that need stomach acid are absorbed (such as certain antifungals and atazanavir), and it interacts with clopidogrel, methotrexate, and warfarin. It should not be used by anyone with a known allergy to substituted benzimidazoles. This information is educational and is not medical advice; talk with your doctor or pharmacist before starting, stopping, or changing how you take Dexilant.

Sources & accuracy

This Dexilant information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Dexilant on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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