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Evenity Syringe — prescription drug image

Evenity

Evenity 1.17ML of 105MG/1.17ML

What is Evenity?

Evenity (romosozumab) is a monoclonal antibody approved for the treatment of osteoporosis in postmenopausal women at high risk of fracture. It works by inhibiting the activity of sclerostin, which results in increased bone formation and decreased bone resorption, thereby improving bone density and reducing the risk of fractures.

Prescription savings · · · ·

What is Evenity ?

Evenity (romosozumab) is a monoclonal antibody approved for the treatment of osteoporosis in postmenopausal women at high risk of fracture. It works by inhibiting the activity of sclerostin, which results in increased bone formation and decreased bone resorption, thereby improving bone density and reducing the risk of fractures.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating, fainting
  • Confusion, seizures, uneven heartbeat, muscle cramps or spasms, numbness and tingling around the mouth, fingertips, or feet
  • New or unusual thigh, hip, or groin pain
  • Numbness or weakness in your arm or leg, or on one side of your body
  • Pain in your lower leg (calf)
  • Sudden or severe headache, problems with vision, speech, or walking
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, cancer, anemia, blood clotting problems, dental problems, or if you had a heart attack or stroke within the last year.
  • This medicine may cause the following problems:Increased risk of heart attack or strokeIncreased risk for a thigh bone fracture
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may cause jaw problems, especially if you have a tooth pulled or have other dental work.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
What is Evenity used for?
Evenity is FDA-approved to treat osteoporosis in postmenopausal women at high risk of fracture, and to increase bone density in men with osteoporosis at high fracture risk. It works by helping the body form new bone.
Why does Evenity have a boxed warning for heart attack and stroke?
Clinical data showed Evenity may increase the risk of heart attack, stroke, and cardiovascular death, which is why the FDA requires its strongest warning label. It is not used in patients who've had a heart attack or stroke in the past year, and providers weigh the risks carefully in patients with other heart risk factors.
How long can you take Evenity (why only 12 doses)?
Evenity treatment is limited to 12 monthly doses. It works by stimulating new bone formation, and that bone-building effect diminishes over time, which is why the course is capped at 12 months rather than continued indefinitely.
What comes after Evenity treatment ends?
Because Evenity is a bone-building medicine used for a limited course, providers typically follow it with an antiresorptive medicine (one that slows bone breakdown) to help maintain the bone density gains achieved during treatment.
How much does Evenity cost without insurance?
Cost varies by pharmacy and insurance situation. Evenity has no generic equivalent, and the manufacturer's savings card generally applies only to patients with commercial insurance, so it may not help if you're uninsured or on Medicare. Enter your ZIP above to see current pharmacy pricing, and ask about manufacturer patient assistance if cost is a barrier.
How much does Evenity cost without insurance?
The price of Evenity without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Evenity?
Common side effects of Evenity may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating, fainting, Confusion, seizures, uneven heartbeat, muscle cramps or spasms, numbness and tingling around the mouth, fingertips, or feet, New or unusual thigh, hip, or groin pain, Numbness or weakness in your arm or leg, or on one side of your body. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Evenity?
Generic versions may be available for Evenity. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Evenity on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Evenity?
The cheapest pharmacy for Evenity depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Evenity near you.

Evenity Coupons & Prices

Evenity 1.17ML of 105MG/1.17ML

Evenity Syringe — prescription drug image
Prescription
Evenity 1.17ml of 105mg/1.17ml (1)
your area ·

If you're comparing an Evenity coupon against the manufacturer's savings program, here's what actually matters: Evenity (romosozumab-aqqg) is a brand-only osteoporosis injection with no generic version, so where you fill it and how you pay can make a real difference — enter your ZIP above to see today's price at pharmacies near you.

What Evenity Is and How It Works

Evenity is a prescription monoclonal antibody (a sclerostin inhibitor) used to build new bone rather than just slow bone loss. It's FDA-approved to treat osteoporosis in postmenopausal women who are at high risk of fracture (for example, those with a prior osteoporotic fracture, multiple risk factors, or who haven't done well on other osteoporosis medicines), and it's also approved to increase bone density in men with osteoporosis at high fracture risk.

Evenity is given as two injections under the skin, once a month, and is administered by a healthcare provider. Treatment is limited to 12 monthly doses total — it's a short, bone-building course, and it's typically followed by a different medicine (an antiresorptive) to help hold onto the bone gains.

Evenity Coupon vs. the Manufacturer Savings Card

Evenity is a brand-name biologic with no generic equivalent available, so the cost conversation centers on how you pay rather than which version you buy. Amgen, the manufacturer, offers an official savings program for Evenity; savings-card programs like this are generally limited to patients with commercial (private) insurance, and the terms, eligibility rules, and any cost caps can change, so check the manufacturer's site directly for current details.

If you're uninsured, on Medicare, or your insurance doesn't cover Evenity, a manufacturer savings card typically won't apply — that's where an Rx.com cash coupon can help, since it works regardless of insurance status. Amgen also offers patient assistance options for those who qualify financially; ask your prescriber's office or Amgen directly about eligibility. Enter your ZIP above to compare cash prices at pharmacies near you.

Evenity and Other Osteoporosis Treatment Options

Evenity is one of several medicines used to manage osteoporosis, and they don't all work the same way. Other bone-building (anabolic) options include Forteo and Tymlos. Antiresorptive medicines, which slow bone breakdown rather than build new bone, include Prolia, Reclast, Boniva, and oral options like Fosamax (alendronate).

Because Evenity's 12-dose course is often followed by an antiresorptive to maintain the bone density gains, your provider may discuss one of these follow-on options with you as part of a longer-term treatment plan. Which medicine is right for you depends on your fracture risk, prior treatments, and other health factors — this isn't a substitute for that conversation.

Evenity Safety Information

Evenity carries a boxed warning — the FDA's most serious safety warning — because it may increase the risk of heart attack, stroke, and cardiovascular death. It should not be used in anyone who has had a heart attack or stroke within the past year, and your provider will weigh the benefits and risks carefully if you have other cardiovascular risk factors.

Evenity also carries warnings about low blood calcium (it shouldn't be used if this isn't corrected first), rare jaw bone problems (osteonecrosis of the jaw), and rare unusual thigh-bone fractures. This is general information, not medical advice — talk with your provider about whether Evenity is appropriate for you.

Sources & accuracy

This Evenity information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Evenity on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.