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Fluconazole Tablet — prescription drug image

Fluconazole

Fluconazole 150MG

Women's Health Care
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What is Fluconazole?

Diflucan prevents and treats fungal infections. Fluconazole is the generic version of Diflucan. The average Diflucan price for a supply of 1, 150 mg oral tablets is about $117. You can use our Rx.com savings offer to get an average Diflucan discount of up to 80 percent off of the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Fluconazole ?

Diflucan prevents and treats fungal infections. Fluconazole is the generic version of Diflucan. The average Diflucan price for a supply of 1, 150 mg oral tablets is about $117. You can use our Rx.com savings offer to get an average Diflucan discount of up to 80 percent off of the retail price at participating pharmacies near you.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash
  • Fainting, dizziness, lightheadedness
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Fast, pounding, or uneven heartbeat
  • Unusual bleeding, bruising, or weakness
  • Changes in skin color, dark freckles, cold feeling, weight loss
  • Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, heart disease, heart failure, heart rhythm problems, cancer, HIV/AIDS, or hereditary problems.
  • This medicine may cause the following problems: Liver problemsSerious skin reactionsChanges in heart rhythm, including QT prolongationAdrenal gland problems
  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control during treatment with this medicine and for at least 1 week after the last dose.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
What is fluconazole used to treat?
Fluconazole is FDA-approved to treat Candida (yeast) infections. These include vaginal yeast infections, oral and esophageal thrush, urinary tract and other systemic Candida infections, and cryptococcal meningitis. It is also used to help prevent candidiasis in people with weakened immune systems, such as bone marrow transplant recipients. Your prescriber will decide if it is appropriate for your infection.
How long does it take for fluconazole (Diflucan) to work for a yeast infection?
For a vaginal yeast infection, fluconazole is often given as a single dose, and many people start to feel relief within a day or two, though it can take several days for symptoms to fully clear. If your symptoms do not improve or come back, contact your prescriber, since a different or longer treatment may be needed. Take fluconazole exactly as directed.
Can you take fluconazole while pregnant?
This is a decision to make with your provider. A single low dose for a vaginal yeast infection is generally considered low-risk, but higher or repeated (chronic) doses during pregnancy have been linked to birth defects, so fluconazole is generally avoided in the first trimester except for serious infections. Tell your prescriber if you are pregnant, could be pregnant, or are breastfeeding before taking it.
What are the most common side effects of fluconazole?
Common side effects can include headache, nausea, stomach upset or pain, diarrhea, and dizziness. More serious but rare effects include liver problems, heart-rhythm changes (QT prolongation), and severe skin or allergic reactions. Get medical help right away if you develop a rash, blistering, yellowing of the skin or eyes, dark urine, or an irregular heartbeat. This is not a complete list, so review side effects with your pharmacist.
Can you drink alcohol while taking fluconazole?
There is no specific interaction that makes a single drink dangerous for everyone, but because fluconazole can affect the liver, it is generally wise to limit or avoid alcohol while taking it, especially if you have any liver concerns. Ask your prescriber or pharmacist what is safe for your situation.
How much does Fluconazole cost without insurance?
The price of Fluconazole without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Fluconazole?
Common side effects of Fluconazole may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Blistering, peeling, or red skin rash, Fainting, dizziness, lightheadedness, Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes, Fast, pounding, or uneven heartbeat. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Fluconazole?
Generic versions may be available for Fluconazole. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Fluconazole on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Fluconazole?
The cheapest pharmacy for Fluconazole depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Fluconazole near you.

Fluconazole Coupons & Prices

Fluconazole 150MG

Women's Health Care
Licensed US providers · Online visit in minutes
Fluconazole Tablet — prescription drug image
Prescription
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Looking for a fluconazole coupon? Fluconazole is the low-cost generic version of Diflucan, a triazole (azole) antifungal used to treat Candida (yeast) infections, including vaginal yeast infections and oral thrush. Because it is already available as a generic, fluconazole is usually inexpensive to fill without insurance, but the cash price can vary widely from one pharmacy to the next. Enter your ZIP above to compare today's fluconazole price across more than 60,000 pharmacies and get a free Rx.com discount coupon you can use at the counter.

What is fluconazole and how does it work?

Fluconazole is a triazole (azole) antifungal medicine, the generic form of the brand Diflucan. It is FDA-approved to treat a range of fungal (Candida) infections, including vaginal yeast infections (vulvovaginal candidiasis), oral and esophageal thrush (oropharyngeal and esophageal candidiasis), urinary tract and other systemic Candida infections, and cryptococcal meningitis. It is also used to help prevent candidiasis in people with weakened immune systems, such as bone marrow transplant recipients.

Fluconazole works by interfering with the fungal cell membrane, which stops the fungus from growing and spreading. It comes as tablets and an oral liquid, and for some infections a single dose is enough while others require a longer course. Always take it exactly as your prescriber directs.

How much does fluconazole cost without insurance?

Fluconazole is a generic, so it is generally one of the more affordable antifungals to fill, even if you are paying cash. That said, pharmacies set their own cash prices, and the same prescription can cost noticeably more at one location than another nearby, which is why comparing before you fill is worth it.

Rx.com compares fluconazole prices across more than 60,000 U.S. pharmacies and shows you a free discount coupon you can present at the register, with no insurance required. Enter your ZIP above to see today's price near you. Because fluconazole is generic, there is no manufacturer copay savings card for it; discount pricing like the Rx.com coupon is typically the most reliable way to lower the cash cost.

Fluconazole alternatives and related antifungals

Fluconazole is the generic equivalent of Diflucan, so switching from the brand to the generic is a common way to lower cost while getting the same active ingredient. Your prescriber may consider a different antifungal depending on the type and location of the infection.

  • Itraconazole — another oral azole antifungal.
  • Ketoconazole — an azole antifungal.
  • Terbinafine — often used for fungal nail and skin infections.
  • Nystatin — used for certain Candida infections of the mouth, skin, or gut.

These medicines are not interchangeable, and the right choice depends on your diagnosis. Ask your prescriber or pharmacist which option fits your situation, then use the ZIP search above to compare prices.

Fluconazole safety and side effects

Fluconazole has no boxed warning, but there are important safety points to know. Rarely it can cause serious liver problems, so it is used with caution in people with liver disease and may require monitoring. It can also affect the heart's rhythm (QT-interval prolongation), so it should not be combined with certain drugs such as erythromycin at higher doses or other medicines that prolong the QT interval. Rare but serious skin reactions (including Stevens-Johnson syndrome and toxic epidermal necrolysis) and allergic reactions have been reported.

Fluconazole interacts with many medications because it affects how the body processes them; examples include warfarin, certain diabetes pills (sulfonylureas), phenytoin, statins, and tacrolimus. It should not be taken with cisapride, pimozide, quinidine, or higher-dose erythromycin. Give your prescriber and pharmacist a full list of everything you take. This is general information, not medical advice, so talk with your provider about whether fluconazole is right for you.

Sources & accuracy

This Fluconazole information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Fluconazole on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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