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Guaifenesin-Dm Bottle — prescription drug image

Guaifenesin-Dm

Guaifenesin-DM

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What is Guaifenesin-Dm?

GuaiFENesin-DM is a medication used to temporarily relieve cough caused by the common cold, flu, or other conditions. It helps reduce coughing but does not treat the underlying cause of the cough.

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What is Guaifenesin-Dm ?

GuaiFENesin-DM is a medication used to temporarily relieve cough caused by the common cold, flu, or other conditions. It helps reduce coughing but does not treat the underlying cause of the cough.

  • dizziness
  • drowsiness
  • nausea
  • vomiting
  • stomach upset
  • headache
  • Do not use if you are allergic to any of the ingredients.
  • Consult a healthcare provider if you have a cough with too much mucus or a chronic cough due to smoking, asthma, or emphysema.
  • Use with caution in people with a history of breathing problems such as asthma or emphysema.
  • Avoid alcohol as it can increase drowsiness.
  • Do not exceed the recommended dosage to prevent potential overdose.
  • Keep out of reach of children.
  • If pregnant or nursing, consult a healthcare professional before use.
What is guaifenesin-DM used for?

Guaifenesin-DM is an over-the-counter combination used for temporary relief of cough and chest congestion associated with the common cold. The guaifenesin thins and loosens mucus so coughs are more productive, and the dextromethorphan calms the cough reflex triggered by throat and bronchial irritation. It relieves symptoms only and does not treat the underlying cause.

Is guaifenesin-DM the same as Mucinex DM?

Mucinex DM is one brand of guaifenesin-DM. The active ingredients are the same combination, guaifenesin plus dextromethorphan, that you find in Robitussin DM, Tussin DM, and many lower-cost store brands. Doses and release times can differ between products, so always check the label of the specific package you buy.

Can you take guaifenesin and dextromethorphan together safely?

Yes, guaifenesin and dextromethorphan are combined on purpose in these products, and taking them together as directed is the intended use. Follow the dosing on the label and do not exceed it. Avoid this combination if you take or recently took an MAO inhibitor, and ask a doctor before use if you have a chronic cough or a cough with heavy phlegm.

How long does it take for guaifenesin-DM to work?

Relief timing varies by person and by product formulation, so check the directions on your specific package for how often to take a dose. Drinking extra water can help the guaifenesin loosen mucus. If your cough lasts more than 7 days, keeps coming back, or comes with fever, rash, or a lasting headache, stop and see a doctor.

Can you take guaifenesin-DM with other cold or allergy medicines?

Be careful, because many cold, cough, and allergy products already contain guaifenesin or dextromethorphan, and combining them can lead to taking too much of the same ingredient. Read the active-ingredient panel on every product and do not double up. Do not use with or within 14 days of an MAO inhibitor, and ask your pharmacist before combining it with other medicines.

How much does guaiFENesin-DM 237ML of 100-10MG/5ML cost without insurance?
The price of guaiFENesin-DM 237ML of 100-10MG/5ML without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of guaiFENesin-DM 237ML of 100-10MG/5ML?
Common side effects of guaiFENesin-DM 237ML of 100-10MG/5ML may include: dizziness, drowsiness, nausea, vomiting, stomach upset. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of guaiFENesin-DM 237ML of 100-10MG/5ML?
Generic versions may be available for guaiFENesin-DM 237ML of 100-10MG/5ML. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search guaiFENesin-DM 237ML of 100-10MG/5ML on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for guaiFENesin-DM 237ML of 100-10MG/5ML?
The cheapest pharmacy for guaiFENesin-DM 237ML of 100-10MG/5ML depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for guaiFENesin-DM 237ML of 100-10MG/5ML near you.

Guaifenesin-Dm Coupons & Prices

Guaifenesin-DM

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Guaifenesin-Dm 237ml of 100-10mg/5ml (0.5)
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Guaifenesin-DM is an over-the-counter combination medicine that pairs guaifenesin, an expectorant that thins and loosens mucus, with dextromethorphan, a cough suppressant. It is sold under brand names like Mucinex DM, Robitussin DM, and Tussin DM, and is used for the temporary relief of cough and chest congestion associated with the common cold. Because you can buy it without a prescription, prices vary widely by store and package size. A free Rx.com guaifenesin-DM coupon can help you compare what the medicine costs at pharmacies near you. Enter your ZIP above to see today's price at pharmacies in your area.

What is guaifenesin-DM and how does it work?

Guaifenesin-DM is a two-in-one combination product. Guaifenesin is an expectorant: it thins and loosens the mucus in your airways so that coughs become more productive and it is easier to clear congestion from your chest. Dextromethorphan (the "DM") is an antitussive, or cough suppressant, that works on the part of the brain that triggers the cough reflex to reduce the urge to cough. Together they aim to relieve a cough that comes with chest congestion, such as the cough that occurs with a common cold.

This medicine treats symptoms only. It does not cure or shorten a cold, and it does not treat the underlying cause of your cough. Products are labeled by age, and adult and extended-release formulations have not been established as safe and effective in children under 12, so always follow the age directions on the specific package you buy.

How to save on guaifenesin-DM with an Rx.com coupon

Guaifenesin-DM is available over the counter, so you do not need a prescription to buy it. Even so, the shelf price for the same combination can differ a lot between pharmacies and between store brands and name brands. In some cases an over-the-counter product like this is cheaper at the pharmacy counter with a discount coupon, or when your provider writes it as a prescription, than it is off the shelf, though this depends on the store and your insurance.

An Rx.com coupon is free to use and requires no insurance or membership. Enter your ZIP code above to see today's price for guaifenesin-DM at pharmacies near you, then show the coupon at the counter. Comparing the coupon price against the shelf price and against generic store brands is the easiest way to find the lowest cost.

Guaifenesin-DM vs. other cough and congestion options

Which product fits depends on your symptoms. If you have chest congestion but do not need to suppress your cough, plain guaifenesin (such as Mucinex) loosens mucus without the cough suppressant. If your main problem is a dry, hacking cough with little mucus, dextromethorphan alone suppresses the cough. Guaifenesin-DM combines both in one dose.

Brand-name versions include Mucinex DM and Robitussin DM, and many pharmacies sell a lower-cost store-brand equivalent with the same two active ingredients. Read the active-ingredient panel so you do not double up on guaifenesin or dextromethorphan from more than one product. If you are unsure which option matches your symptoms, ask your pharmacist.

Safety and side effects

Guaifenesin-DM has no boxed warning, but a few points matter. Do not use it with, or within 14 days of, an MAO inhibitor (a type of antidepressant or Parkinson's medicine), because dextromethorphan can interact with MAOIs and other serotonergic drugs and raise the risk of serotonin syndrome or a blood-pressure reaction. Ask a doctor before use if you have a chronic cough from smoking, asthma, emphysema, or chronic bronchitis, or a cough with a lot of phlegm.

Stop and consult a doctor if your cough lasts more than 7 days, goes away and comes back, or comes with fever, rash, or a persistent headache, as these can signal a condition that needs treatment. Common side effects include dizziness, drowsiness, nausea, and vomiting. Dextromethorphan can be misused at high doses, so use only as directed and do not exceed the labeled dose. This is general information, not medical advice; talk with your provider or pharmacist about your situation.

Sources & accuracy

This Guaifenesin-Dm information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Guaifenesin-Dm on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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