Harvoni Coupons & Prices

Looking for a Harvoni coupon? Harvoni (ledipasvir/sofosbuvir) is a once-daily tablet used to treat chronic hepatitis C, and a full course can be costly at the pharmacy. Rx.com offers a free cash discount coupon you can use whether or not you have insurance. Enter your ZIP above to see today's price at pharmacies near you, and read on to understand your options, including the lower-cost authorized generic.

What is Harvoni and how does it work?

Harvoni is a fixed-dose combination of two direct-acting antiviral medicines: ledipasvir, an NS5A inhibitor, and sofosbuvir, an NS5B polymerase inhibitor. Together they block proteins the hepatitis C virus needs to copy itself, which lowers the amount of virus in your body and, for most people, clears the infection. It is FDA-approved to treat chronic hepatitis C virus (HCV) infection in adults and children 3 years and older with HCV genotype 1, 4, 5, or 6, including those without cirrhosis or with compensated cirrhosis. For certain genotype 1 patients with decompensated cirrhosis, and for genotype 1 or 4 liver transplant recipients, it is used in combination with ribavirin.

Harvoni is taken as one tablet once a day, usually for 8 to 24 weeks depending on your genotype, treatment history, and liver health. A cure is measured as a sustained virologic response, meaning the virus stays undetectable after treatment ends; for genotype 1, reported cure rates are roughly 94 to 99 percent. Your provider decides the right length of treatment for you.

Harvoni cost: manufacturer savings card vs. Rx.com cash coupon

The biggest cost lever for most people is the generic. An authorized generic of ledipasvir/sofosbuvir is available and is typically far less expensive than brand-name Harvoni for the same medicine. Ask your provider or pharmacist whether the generic is appropriate for you, then enter your ZIP above to compare today's cash price on both the brand and the generic.

Harvoni's maker, Gilead, runs an official copay savings program (Support Path) for eligible patients, plus a patient assistance program for those who qualify. Manufacturer copay cards are generally limited to people with commercial (private) insurance and are not available if you have Medicare, Medicaid, or other government coverage; terms and eligibility vary and can change, so check the manufacturer's official site for current details. If you are uninsured, covered by Medicare or Medicaid, or your copay card is declined, the Rx.com cash coupon is an alternative you can use at the pharmacy counter. It is not insurance; it is a discount on the cash price. Enter your ZIP above to see what you would pay today.

Harvoni alternatives and related hepatitis C treatments

Harvoni is one of several direct-acting antiviral regimens for hepatitis C. The right choice depends on your HCV genotype, whether you have cirrhosis, and your treatment history, so this decision belongs to you and your provider. Other options your prescriber may consider include:

• Epclusa (sofosbuvir/velpatasvir), a pan-genotypic once-daily regimen.
• Mavyret (glecaprevir/pibrentasvir), a pan-genotypic option often used for shorter 8-week courses.
• Sovaldi (sofosbuvir), used in combination with other antivirals.
• Vosevi (sofosbuvir/velpatasvir/voxilaprevir), often used when a prior treatment did not clear the virus.

You can look up the current cash price for any of these on Rx.com by entering your ZIP above.

Harvoni safety and side effects

Harvoni carries a boxed warning for the risk of hepatitis B virus (HBV) reactivation in people who are coinfected with HCV and HBV, which in rare cases can be serious or fatal. Because of this, everyone should be tested for hepatitis B before starting Harvoni and monitored during and after treatment. Serious slow heartbeat (symptomatic bradycardia) has occurred when Harvoni is taken with the heart medicine amiodarone, so that combination is not recommended. Harvoni is also not recommended with rifampin or St. John's wort, which can lower its levels and make it less effective, and acid-reducing medicines such as antacids, H2 blockers, and proton pump inhibitors can reduce absorption and require careful timing.

The most common side effects reported are fatigue, headache, and weakness (asthenia). This is general information, not medical advice. Tell your provider about all the medicines and supplements you take, and talk with them or your pharmacist about whether Harvoni is right for you.