Hydrocortisone Butyrate Coupons & Prices

Hydrocortisone butyrate is the generic name behind the prescription topical corticosteroid sold as Locoid, Locoid Lipocream, and Locoid Lotion, used to calm the inflammation and itching of eczema and other corticosteroid-responsive skin conditions. If you're comparing a hydrocortisone butyrate coupon before you fill, keep in mind that pharmacy cash prices for the same generic tube or bottle can vary widely from one store to the next — Rx.com compares pricing across more than 60,000 U.S. pharmacies, so enter your ZIP code above to see today's price near you.

What Is Hydrocortisone Butyrate?

Hydrocortisone butyrate is a prescription-only topical glucocorticoid classified as a medium-potency corticosteroid (some formulations, such as the cream, are rated even lower, in the low-to-medium range). It's FDA-approved to relieve the inflammation and itching of corticosteroid-responsive dermatoses — such as eczema (atopic dermatitis) and other corticosteroid-responsive conditions — in adults, and the Lipocream and lotion formulations are also approved to treat mild-to-moderate atopic dermatitis in patients as young as 3 months old. It's typically applied in a thin layer to the affected skin two to three times a day, exactly as your prescriber directs.

It's sold under the brand name Locoid, as well as Locoid Lipocream and Locoid Lotion, and is also available generically. The vehicle (cream, lipocream, or lotion) affects how the product feels and spreads on skin, so your prescriber or pharmacist may choose a specific form based on where and how you'll be using it.

Hydrocortisone Butyrate Cost and How to Compare Pharmacy Prices

Generic hydrocortisone butyrate is available and is what most prescriptions for this medication are filled with. Cash prices for topical corticosteroids like this one can differ significantly from pharmacy to pharmacy, even within the same city, so it's worth comparing before you fill rather than assuming any one pharmacy has the best price. Enter your ZIP code above to see current pricing at pharmacies near you and find the lowest price for your specific formulation and quantity.

How Hydrocortisone Butyrate Compares to Other Topical Corticosteroids

Hydrocortisone butyrate is generally classified as a medium-potency topical corticosteroid, with some formulations — such as the cream — rated even lower, closer to low-to-medium potency. Lower-potency hydrocortisone is another option your provider might consider for milder or more sensitive-skin cases. Other prescription topical corticosteroids sit at different points on the potency scale: desonide is a lower-potency option, while betamethasone dipropionate and especially clobetasol propionate are substantially more potent than hydrocortisone butyrate — clobetasol propionate is one of the most potent (ultra-high/super-potent) topical corticosteroids available, so it isn't comparable in strength to hydrocortisone butyrate despite both being prescription topical steroids. Triamcinolone acetonide and mometasone furoate vary in potency depending on their specific strength and formulation. All of these treat similar corticosteroid-responsive skin conditions at their own strengths and in their own formulations.

Potency, approved uses, and dosing differ by drug and by formulation, so a switch between any of these should be made by your prescriber, not on your own — don't substitute one topical steroid for another without medical guidance.

Hydrocortisone Butyrate Safety Information

Hydrocortisone butyrate does not carry an FDA boxed warning, but like all topical corticosteroids it carries class warnings that are worth understanding. Prolonged use, use over a large area of skin, use under an occlusive dressing, or use on broken or damaged skin can lead to reversible suppression of the body's HPA axis (the hormonal system that regulates cortisol) — children are at higher risk because of their larger skin-surface-to-body-mass ratio. Rarely, this can progress to Cushing syndrome or elevated blood sugar. The label notes that use beyond two weeks should be weighed against this risk, so don't use it longer than your prescriber directs.

• Common local reactions include burning, itching, irritation, and dryness; skin thinning, stretch marks, or visible blood vessels can occur with prolonged use
• Avoid the face, groin, and underarms unless your prescriber specifically tells you to use it there
• Don't use occlusive (airtight) dressings unless instructed, and don't use it near the eyes
• Don't apply other topical products to the same area unless your clinician has approved it

This is general information, not medical advice — talk to your prescriber or pharmacist about how it applies to you.