Neomycin-Polymyxin-Hc
Neomycin-Polymyxin-HC 10ML of 3.5-10000-1
What is Neomycin-Polymyxin-Hc?
If you are diagnosed with on outer ear infection, your doctor might prescribe neomycin/polymyxin/hydrocortisone. The medication is applied as drops in the ear. You might need help from another person to make sure the drops get placed in your ear correctly.Side Effects
- Severe dizziness or loss of balance
- Change in how much or how often you urinate
- Change in hearing, ringing in the ears, or feeling of fullness in the ears
Warnings
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Tell your doctor if you are pregnant or breastfeeding, or if you have a punctured eardrum or any other ear problems.
- The solution form of this medicine contains potassium metabisulfite. Tell your doctor if you have a sulfite allergy before you start using this medicine.
- If your symptoms do not improve after 7 days or if they become worse, check with your doctor.
Prescription savings · · · ·
What is Neomycin-Polymyxin-Hc ?
If you are diagnosed with on outer ear infection, your doctor might prescribe neomycin/polymyxin/hydrocortisone. The medication is applied as drops in the ear. You might need help from another person to make sure the drops get placed in your ear correctly.- Severe dizziness or loss of balance
- Change in how much or how often you urinate
- Change in hearing, ringing in the ears, or feeling of fullness in the ears
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Skin rash, redness, swelling, or intense itching in or around the ear
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Tell your doctor if you are pregnant or breastfeeding, or if you have a punctured eardrum or any other ear problems.
- The solution form of this medicine contains potassium metabisulfite. Tell your doctor if you have a sulfite allergy before you start using this medicine.
- If your symptoms do not improve after 7 days or if they become worse, check with your doctor.
Neomycin-Polymyxin-Hc Coupons & Prices
Neomycin-Polymyxin-HC 10ML of 3.5-10000-1
Neomycin and polymyxin B sulfates with hydrocortisone is a prescription ear drop (otic suspension) used to treat certain outer ear infections. A neomycin polymyxin hydrocortisone coupon can help lower your cost at the pharmacy, since cash prices for this generic vary from one pharmacy to another. Enter your ZIP above to see today's price near you.
What Is Neomycin/Polymyxin B/Hydrocortisone and How Does It Work?
This prescription otic (ear) suspension combines two antibiotics, neomycin and polymyxin B, with the steroid hydrocortisone. It's used to treat bacterial infections of the outer ear canal and to help relieve the redness, swelling, and discomfort that come with them. The antibiotics work against the bacteria causing the infection while the hydrocortisone reduces inflammation. This combination has historically been sold in the U.S. under the brand name Cortisporin Otic Suspension, and it's dispensed today mainly as a generic.
Comparing Prices
Because this is a generic prescription product, cash prices can vary a lot between pharmacies. Rx.com compares prices at more than 60,000 U.S. pharmacies so you can find a lower price or use a free coupon at checkout, whether or not you have insurance.
- Prices vary by pharmacy and bottle size
- A coupon can help if you're uninsured or your copay is high
- Ask your pharmacist about availability, since some ear-drop products see periodic supply gaps
Alternatives for Ear Infections
Other prescription ear-drop options your provider might consider include ofloxacin otic solution or ciprofloxacin-based otic drops, which don't contain neomycin. Your provider chooses based on the type of infection, whether your eardrum is intact, and your history of drug allergies.
Safety Information
This medication should not be used if you have a perforated (ruptured) eardrum, since the ingredients can be absorbed and neomycin has been linked to permanent hearing loss with prolonged or inappropriate use in that setting. Tell your provider about any known allergy to neomycin or related antibiotics before using this product. This is general information, not medical advice — talk to your provider or pharmacist about your specific situation.
This Neomycin-Polymyxin-Hc information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Neomycin-Polymyxin-Hc on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.