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Oxtellar Xr Tablet — prescription drug image

Oxtellar Xr

Oxtellar XR 600MG

Women's Health Care
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What is Oxtellar Xr?

Oxtellar XR is used to treat partial seizures in certain patients. There is not a generic version currently available. The average Oxtellar XR cash price can be expensive at about $300 for a supply of 30, 300 mg extended-release tablets. You can lower your high Oxtellar XR cost by up to 80% by using our free Oxtellar XR savings card at a local pharmacy that participates with Rx.com.

Prescription savings · · · ·

What is Oxtellar Xr ?

Oxtellar XR is used to treat partial seizures in certain patients. There is not a generic version currently available. The average Oxtellar XR cash price can be expensive at about $300 for a supply of 30, 300 mg extended-release tablets. You can lower your high Oxtellar XR cost by up to 80% by using our free Oxtellar XR savings card at a local pharmacy that participates with Rx.com.
  • Fever, skin rash, or swollen glands in your armpits, neck, or groin
  • Unusual bleeding, bruising, or weakness
  • Worsening of seizures
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Confusion, weakness, muscle twitching
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Unusual thoughts or behaviors, thoughts of hurting yourself, or feeling depressed, irritable, nervous, restless
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or a history of depression or mental health problems. Tell your doctor if you are allergic to carbamazepine or tartrazine.
  • This medicine may cause the following problems:Low sodium levels in the bloodDrug reaction with eosinophilia and systemic symptoms (DRESS), which may damage organs including the liver, kidney, or heartSerious skin reactionsChanges in mood or behavior, including thoughts or attempts of suicideNew or worsening seizures
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely. The seizures might become more frequent if you suddenly stop using this medicine.
  • Birth control that uses hormones may not work as well while you are using this medicine. Use a different type of birth control if you need to. Talk with your doctor if you have questions.
  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is Oxtellar XR used for?
Oxtellar XR is FDA-approved to treat partial-onset (focal) seizures in adults and children 6 years of age and older. It can be used alone (monotherapy) or added to other seizure medicines (adjunctive therapy) in that age group. Oxcarbazepine is sometimes used off-label for bipolar disorder or nerve pain such as trigeminal neuralgia, but those uses are not FDA-approved and are not supported by the Oxtellar XR label.
What is the difference between Oxtellar XR and Trileptal (regular oxcarbazepine)?
Both contain the same active drug, oxcarbazepine. Trileptal is the immediate-release form and is usually taken twice a day. Oxtellar XR is an extended-release tablet taken once a day, and it must be taken on an empty stomach, 1 hour before or 2 hours after a meal. They are not interchangeable tablet-for-tablet; only your prescriber should decide which form and dose is right for you.
Is there a generic for Oxtellar XR?
Yes. FDA-approved generic oxcarbazepine extended-release tablets are available in 150 mg, 300 mg and 600 mg. Asking for the generic is usually the biggest way to lower your cost. Prices still vary by pharmacy, so enter your ZIP above to compare today's prices near you and use the free coupon.
What are the most common side effects of Oxtellar XR?
The most common side effects are dizziness, sleepiness, headache, nausea, vomiting, double vision or other vision changes, unsteadiness (ataxia) and fatigue. Get emergency help for signs of a serious allergic reaction such as swelling of the lips, eyelids or throat, or any spreading rash or blistering. Contact your doctor about new or worsening depression or mood changes. This is not a complete list; ask your pharmacist.
Why does Oxtellar XR have to be taken on an empty stomach?
Food changes how much of the extended-release drug your body absorbs, so the label directs that Oxtellar XR be taken on an empty stomach, 1 hour before a meal or 2 hours after a meal. Taking it the same way each day helps keep your drug levels steady. Follow your prescriber's instructions exactly.
Is Oxtellar XR a controlled substance?
No. Oxtellar XR is not a controlled substance and has no DEA schedule. It is a prescription anticonvulsant. Even so, it should never be stopped suddenly; it must be tapered gradually under your doctor's direction to avoid an increase in seizures or status epilepticus.
How much does Oxtellar Xr cost without insurance?
The price of Oxtellar Xr without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Oxtellar Xr?
Common side effects of Oxtellar Xr may include: Fever, skin rash, or swollen glands in your armpits, neck, or groin, Unusual bleeding, bruising, or weakness, Worsening of seizures, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Blistering, peeling, red skin rash. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Oxtellar Xr?
Generic versions may be available for Oxtellar Xr. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Oxtellar Xr on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Oxtellar Xr?
The cheapest pharmacy for Oxtellar Xr depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Oxtellar Xr near you.

Oxtellar Xr Coupons & Prices

Oxtellar XR 600MG

Women's Health Care
Licensed US providers · Online visit in minutes
Oxtellar Xr Tablet — prescription drug image
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Oxtellar Xr 300mg (14)
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An Oxtellar XR coupon from Rx.com can lower the cash price of oxcarbazepine extended-release tablets (150 mg, 300 mg and 600 mg) at pharmacies near you. Oxtellar XR is the once-daily extended-release brand of oxcarbazepine from Supernus Pharmaceuticals, FDA-approved for partial-onset (focal) seizures in adults and children 6 years and older. Prices for this medicine vary a lot from pharmacy to pharmacy, so enter your ZIP code above to see today's price at pharmacies in your area and bring the free coupon with you when you fill your prescription.

What is Oxtellar XR and how does it work?

Oxtellar XR is an extended-release tablet form of oxcarbazepine, an anticonvulsant (antiepileptic) medicine. It is a carboxamide derivative, structurally related to carbamazepine, and it works by blocking voltage-sensitive sodium channels in the brain, which helps calm the abnormal electrical activity that causes seizures.

Oxtellar XR is FDA-approved for the treatment of partial-onset (focal) seizures in patients 6 years of age and older. It is approved both as monotherapy (used alone) and as adjunctive therapy (added to other seizure medicines) in that age group. The extended-release tablets come in 150 mg, 300 mg and 600 mg strengths and are taken once a day on an empty stomach, either 1 hour before or 2 hours after a meal. You may also hear about oxcarbazepine being used for bipolar disorder or nerve pain such as trigeminal neuralgia. Those uses are off-label, are not FDA-approved, and are not supported by the Oxtellar XR label. Only your prescriber can decide what is right for you.

Oxtellar XR cost: manufacturer savings card vs. the Rx.com cash coupon

Supernus, the maker of Oxtellar XR, runs an official co-pay savings program, and information about it is posted on the manufacturer's own Oxtellar XR website. Programs like this are generally limited to people with commercial (non-government) insurance, and the eligibility rules, expiration dates and benefit terms vary, so read the manufacturer's terms carefully. People with Medicare, Medicaid or other government coverage typically do not qualify. Supernus also lists a patient assistance program on its site for patients who cannot afford their medicine, which is worth asking your prescriber's office about.

The Rx.com coupon works differently. It is a free cash-discount coupon, not insurance, so it can be used if you are uninsured, if you have Medicare, or if the manufacturer card is declined at the counter. You cannot combine it with insurance on the same fill, but you can ask the pharmacist to run the cash price with the coupon and compare. Prices differ meaningfully between pharmacies, so enter your ZIP above to see today's price near you.

Is there a generic? Oxtellar XR alternatives

Yes. FDA-approved generic oxcarbazepine extended-release tablets are available in 150 mg, 300 mg and 600 mg (Aurobindo received approval for all three strengths). Asking your pharmacist to fill the generic extended-release tablet is usually the single biggest savings lever on this prescription, and a cash coupon can be applied to the generic as well. Prices still vary by pharmacy, so it is worth comparing.

The immediate-release form of oxcarbazepine is sold as Trileptal (Novartis) and as generic oxcarbazepine tablets, which are taken twice daily rather than once. Other antiepileptic medicines your prescriber may discuss for focal seizures include carbamazepine (Tegretol), lamotrigine (Lamictal), levetiracetam (Keppra) and topiramate. Never switch or stop a seizure medicine on your own; changes should be made only by your prescriber.

Oxtellar XR safety, side effects and interactions

Oxtellar XR does not carry a boxed warning. Its label does include important warnings and precautions. Hyponatremia (low blood sodium) can develop and may need a dose reduction or stopping the drug, so your doctor may check your sodium level, especially if you take other medicines that lower sodium. Rare but serious anaphylaxis and angioedema can involve the lips, eyelids, larynx and glottis and can be fatal; get emergency help and stop the drug if this happens. Serious skin reactions including Stevens-Johnson syndrome and toxic epidermal necrolysis have occurred (median onset about 19 days), and people who carry the HLA-B*1502 allele, more common in people of Han Chinese, Thai, Filipino, Malaysian and some other Asian ancestries, are at higher risk. Genetic testing before starting is recommended for those patients. About 25 to 30 percent of people who are hypersensitive to carbamazepine also react to oxcarbazepine. DRESS (multi-organ hypersensitivity) and rare blood problems such as pancytopenia, agranulocytosis and leukopenia have also been reported.

Like other antiepileptic drugs, oxcarbazepine carries a class risk of suicidal thoughts and behavior (about 1 in 500 patients in pooled trials), so watch for new or worsening depression or mood changes and tell your doctor. Do not stop Oxtellar XR abruptly; it should be tapered gradually to avoid more frequent seizures or status epilepticus. Oxcarbazepine can make hormonal birth control less effective, so an additional non-hormonal method is needed. Drowsiness and dizziness are worse with alcohol and other CNS depressants. Common side effects include dizziness, sleepiness, headache, nausea, vomiting, double vision or other vision changes, unsteadiness (ataxia) and fatigue. This is a summary, not medical advice; talk with your doctor or pharmacist about your full medicine list.

Sources & accuracy

This Oxtellar Xr information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Oxtellar Xr on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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