Paricalcitol
Paricalcitol 1MCG
What is Paricalcitol?
Paricalcitol is a prescription medication primarily used to manage secondary hyperparathyroidism in patients with chronic kidney disease. By regulating calcium and phosphorus levels, it helps maintain bone health. Common side effects include nausea, headache, and fatigue. Users can find cost savings and coupons for paricalcitol through Rx.com, where they can also connect with licensed providers for efficient prescription refills and mail-order options.Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Feeling tired, trouble thinking clearly, constipation, nausea, vomiting
- Increase in how much or how often you urinate, increase thirst
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, bone disease, heart disease, heart rhythm problems (such as arrhythmia), or seizures.
- This medicine may cause the following problems:Hypercalcemia (high levels of calcium in the blood)Increase aluminum in the blood and may cause harm to your bones
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Dry mouth, increased thirst, muscle cramps, nausea, or vomiting.
Prescription savings · · · ·
What is Paricalcitol ?
Paricalcitol is a prescription medication primarily used to manage secondary hyperparathyroidism in patients with chronic kidney disease. By regulating calcium and phosphorus levels, it helps maintain bone health. Common side effects include nausea, headache, and fatigue. Users can find cost savings and coupons for paricalcitol through Rx.com, where they can also connect with licensed providers for efficient prescription refills and mail-order options.- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Feeling tired, trouble thinking clearly, constipation, nausea, vomiting
- Increase in how much or how often you urinate, increase thirst
- Sudden weight loss or loss of appetite, diarrhea
- Swelling in your hands, ankles, or feet
- Trouble breathing
- Stuffy or runny nose.
- Trouble sleeping.
- Unusual weakness or sleepiness.
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, bone disease, heart disease, heart rhythm problems (such as arrhythmia), or seizures.
- This medicine may cause the following problems:Hypercalcemia (high levels of calcium in the blood)Increase aluminum in the blood and may cause harm to your bones
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Dry mouth, increased thirst, muscle cramps, nausea, or vomiting.
- Eye redness, or sensitivity to light.
- Fast, slow, or pounding heartbeat.
- Feeling confused, depressed, or nervous.
- Fever, chills, cough, sore throat, and body aches.
- Lightheadedness, dizziness, or fainting.
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet.
- Severe muscle pain or bone pain.
- Sudden and severe stomach pain.
- Sudden weight loss or loss of appetite.
- Swelling in your hands, ankles, or feet.
Paricalcitol Coupons & Prices
Paricalcitol 1MCG
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Paricalcitol prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 1mcg · Capsule | 30 | $334.49 | $37.69 |
| 2mcg · Capsule | 30 | $462.99 | $77.36 |
| 4mcg · Capsule | 30 | $635.99 | $193.02 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
Paricalcitol capsules (the generic version of Zemplar) are a vitamin D analog prescribed for people with chronic kidney disease to prevent or treat secondary hyperparathyroidism. If you're comparing a paricalcitol coupon, cash prices for this oral capsule can vary a lot from one pharmacy to the next, so it's worth comparing before you fill. Rx.com compares prices at 60,000+ pharmacies — enter your ZIP above to see today's price near you.
What Is Paricalcitol and How Does It Work?
Paricalcitol is a synthetic vitamin D analog available as an oral soft-gel capsule (1 mcg, 2 mcg, or 4 mcg), sold under the brand name Zemplar and as a generic. This page covers the oral capsule form only — paricalcitol is also available as an IV injection given during dialysis sessions in a clinic, but that form has its own separate dosing and isn't something you'd fill as a retail prescription. The oral capsules are FDA-approved for adults and pediatric patients 10 years and older, for the prevention and treatment of secondary hyperparathyroidism associated with chronic kidney disease stages 3–4 (not yet on dialysis) and stage 5 (on hemodialysis or peritoneal dialysis). It works by activating vitamin D receptors to help regulate parathyroid hormone levels without raising calcium and phosphorus as much as some older vitamin D therapies.
How to Save on Paricalcitol
Because paricalcitol is a generic medication, prices can vary widely by pharmacy — there isn't one manufacturer copay card to rely on the way there is for many brand-name drugs. Comparing pharmacy cash prices is often the best way to find savings, especially if your insurance plan's copay is high or you're paying out of pocket. Rx.com compares prices at 60,000+ pharmacies to help you find a lower price near you.
Paricalcitol vs. Other Secondary Hyperparathyroidism Treatments
- Calcitriol — another active vitamin D therapy used for secondary hyperparathyroidism in CKD, though it tends to raise calcium and phosphorus more than paricalcitol.
- Cinacalcet — a calcimimetic that lowers parathyroid hormone through a different mechanism, often used in dialysis patients.
- Sevelamer — a phosphate binder sometimes used alongside vitamin D therapy to help manage phosphorus levels in CKD.
Your nephrologist chooses your regimen based on your kidney function, lab values, and dialysis status — these aren't interchangeable without medical supervision.
Safety Information
Paricalcitol can cause hypercalcemia (high blood calcium), especially if combined with calcium supplements, other vitamin D products, or too much dietary calcium — your provider will monitor your calcium, phosphorus, and parathyroid hormone levels regularly while you're on it. It can also increase the risk of digitalis (digoxin) toxicity in patients taking that heart medication, so tell your provider about all your medications. Overcorrecting parathyroid hormone too far can lead to adynamic bone disease. Common side effects can include nausea and headache. This isn't a complete list of risks — talk to your nephrologist or pharmacist about your specific labs and health history.
This Paricalcitol information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Paricalcitol on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.
