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Selenium Sulfide Bottle — prescription drug image

Selenium Sulfide

Selenium Sulfide 120ML of 2.5%

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What is Selenium Sulfide?

Selenium Sulfide is a generic drug used to treat dandruff and other skin infections caused by fungus. The average cost of Selenium Sulfide is about $18 for 120 ml of 2.5%. However, you can use our free Rx.com coupon card to save significantly on Selenium Sulfide prices at a participating pharmacy near you.

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What is Selenium Sulfide ?

Selenium Sulfide is a generic drug used to treat dandruff and other skin infections caused by fungus. The average cost of Selenium Sulfide is about $18 for 120 ml of 2.5%. However, you can use our free Rx.com coupon card to save significantly on Selenium Sulfide prices at a participating pharmacy near you.
  • Oily or dry hair or scalp
  • Change in hair color
  • Hair loss
  • Skin irritation
  • If you are pregnant or breastfeeding, talk to your doctor before using selenium sulfide.
What is selenium sulfide used for?
Selenium sulfide is FDA-approved for the topical treatment of tinea versicolor, seborrheic dermatitis of the scalp, and dandruff. It works by slowing skin cell turnover and acting against the Malassezia yeast associated with these conditions.
Is selenium sulfide the same as Selsun Blue?
They contain the same active ingredient, but at different strengths. Selsun Blue is an over-the-counter product with 1% selenium sulfide, used for dandruff and an itchy, flaky scalp. The prescription version is a stronger 2.5% lotion, sold generically, used for conditions like tinea versicolor and seborrheic dermatitis.
How do you use selenium sulfide 2.5% lotion for tinea versicolor?
Per the product label, the lotion is applied to the affected area and left on for about 10 minutes before being rinsed off thoroughly, since leaving it on the genital area or skin folds too long can cause irritation. Always follow the specific instructions on your prescription label or ask your pharmacist, since exact directions can vary.
Do you need a prescription for selenium sulfide?
It depends on the strength. The 2.5% lotion is prescription-only in the U.S. A 1% strength, such as Selsun Blue, is available over the counter without a prescription for dandruff.
What are the side effects of selenium sulfide shampoo?
Common issues include skin or scalp irritation and contact dermatitis, plus discoloration of hair. It can also discolor jewelry, such as gold. Avoid contact with the eyes and mucous membranes, since it can cause irritation or burning, and don't use it on inflamed, broken, or oozing skin.
How much does Selenium Sulfide cost without insurance?
The price of Selenium Sulfide without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Selenium Sulfide?
Common side effects of Selenium Sulfide may include: Oily or dry hair or scalp, Change in hair color, Hair loss, Skin irritation. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Selenium Sulfide?
Generic versions may be available for Selenium Sulfide. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Selenium Sulfide on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Selenium Sulfide?
The cheapest pharmacy for Selenium Sulfide depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Selenium Sulfide near you.

Selenium Sulfide Coupons & Prices

Selenium Sulfide 120ML of 2.5%

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Selenium Sulfide Bottle — prescription drug image
Prescription
Selenium Sulfide 120ml of 2.5% (1)
your area ·
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a selenium sulfide coupon? Selenium sulfide is a topical antifungal and antiseborrheic agent, and a generic version of the prescription-strength 2.5% lotion is already on the market from manufacturers like Padagis. Even so, the price for the same generic fill can vary a lot from one pharmacy to the next, so it's worth comparing. Rx.com checks selenium sulfide pricing at more than 60,000 pharmacies nationwide, so enter your ZIP above to see today's price near you.

What Is Selenium Sulfide and How Does It Work?

Selenium sulfide is a topical antifungal / antiseborrheic agent. It's FDA-approved to treat tinea versicolor, seborrheic dermatitis of the scalp, and dandruff. It works through a cytostatic effect that slows down the turnover of skin and follicle cells, and it also has activity against the Malassezia (Pityrosporum) yeast that's implicated in dandruff and tinea versicolor.

Strength matters here. The 2.5% lotion is prescription-only in the U.S., sold generically (for example, by Padagis) and historically under the brand name Selsun. A lower 1% strength is sold over the counter for dandruff and an itchy, flaky scalp, marketed as Selsun Blue.

Selenium Sulfide Cost Without Insurance

A generic version of the 2.5% selenium sulfide lotion is already available, so there's no brand-only pricing barrier to work around. What does vary is the price different pharmacies charge for the same generic fill, sometimes quite a bit, which is why it's worth comparing before you pick a pharmacy. Enter your ZIP code above to see today's price at pharmacies near you.

If your provider has you using the 1% over-the-counter strength (Selsun Blue) instead for routine dandruff, that product doesn't require a prescription and is sold directly at retail and grocery pharmacies, so no coupon is needed for it.

Selenium Sulfide vs. Other Antifungal and Antiseborrheic Options

Selenium sulfide isn't the only topical option for fungal or scalp-related skin conditions, and your provider may consider alternatives depending on the diagnosis. Other topical antifungals used for related conditions include ketoconazole and ciclopirox shampoos or creams, which are also used for seborrheic dermatitis and tinea versicolor, as well as clotrimazole and terbinafine for other fungal skin infections.

If itching or inflammation from seborrheic dermatitis needs short-term symptomatic relief, a provider may also add a topical corticosteroid like hydrocortisone. Each of these works differently, so which one is right for you depends on your specific diagnosis, not just cost.

Selenium Sulfide Safety Information

Selenium sulfide is for external, topical use only. Avoid getting it in your eyes or on mucous membranes, since contact can cause irritation or a burning sensation, and don't apply it to skin that's acutely inflamed, broken, or oozing, which can increase how much is absorbed into the body. When it's used on the body for tinea versicolor, it may irritate the genital area and skin folds, so it's important to rinse thoroughly after the roughly 10-minute application the label describes.

Possible side effects include contact dermatitis and skin or scalp irritation, along with discoloration of hair, and it can also discolor jewelry such as gold. Selenium sulfide does not carry an FDA boxed warning and is not a controlled substance. This information isn't a substitute for medical advice; talk to your doctor or pharmacist about whether it's right for you.

Sources & accuracy

This Selenium Sulfide information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Selenium Sulfide on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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